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Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

Lüttgen H, Rohdich F, Herz S, Wungsintaweekul J, Hecht S, Schuhr CA, Fellermeier M, Sagner S, Zenk MH, Bacher A, Eisenreich W.

Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1062-7.


Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate.

Herz S, Wungsintaweekul J, Schuhr CA, Hecht S, Luttgen H, Sagner S, Fellermeier M, Eisenreich W, Zenk MH, Bacher A, Rohdich F.

Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2486-90.


Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol.

Rohdich F, Wungsintaweekul J, Fellermeier M, Sagner S, Herz S, Kis K, Eisenreich W, Bacher A, Zenk MH.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11758-63.


Early steps of deoxyxylulose phosphate pathway in chromoplasts of higher plants.

Fellermeier M, Sagner S, Spiteller P, Spiteller M, Zenk MH.

Phytochemistry. 2003 Sep;64(1):199-207.


Biosynthesis of terpenoids: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from tomato.

Rohdich F, Wungsintaweekul J, Luttgen H, Fischer M, Eisenreich W, Schuhr CA, Fellermeier M, Schramek N, Zenk MH, Bacher A.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8251-6.


Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids.

Steinbacher S, Kaiser J, Wungsintaweekul J, Hecht S, Eisenreich W, Gerhardt S, Bacher A, Rohdich F.

J Mol Biol. 2002 Feb 8;316(1):79-88.


LytB, a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli.

Altincicek B, Kollas A, Eberl M, Wiesner J, Sanderbrand S, Hintz M, Beck E, Jomaa H.

FEBS Lett. 2001 Jun 15;499(1-2):37-40.


Identification of gcpE as a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis in Escherichia coli.

Campos N, Rodríguez-Concepción M, Seemann M, Rohmer M, Boronat A.

FEBS Lett. 2001 Jan 19;488(3):170-3.


Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis.

Gabrielsen M, Bond CS, Hallyburton I, Hecht S, Bacher A, Eisenreich W, Rohdich F, Hunter WN.

J Biol Chem. 2004 Dec 10;279(50):52753-61. Epub 2004 Oct 2.


Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway.

Carretero-Paulet L, Ahumada I, Cunillera N, Rodríguez-Concepción M, Ferrer A, Boronat A, Campos N.

Plant Physiol. 2002 Aug;129(4):1581-91.


The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: studies on the mechanisms of the reactions catalyzed by IspG and IspH protein.

Rohdich F, Zepeck F, Adam P, Hecht S, Kaiser J, Laupitz R, Gräwert T, Amslinger S, Eisenreich W, Bacher A, Arigoni D.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1586-91. Epub 2003 Feb 5.


Biosynthesis of terpenoids: efficient multistep biotransformation procedures affording isotope-labeled 2C-methyl-D-erythritol 4-phosphate using recombinant 2C-methyl-D-erythritol 4-phosphate synthase.

Hecht S, Wungsintaweekul J, Rohdich F, Kis K, Radykewicz T, Schuhr CA, Eisenreich W, Richter G, Bacher A.

J Org Chem. 2001 Nov 16;66(23):7770-5.


Biosynthesis of isoprenoids. purification and properties of IspG protein from Escherichia coli.

Zepeck F, Gräwert T, Kaiser J, Schramek N, Eisenreich W, Bacher A, Rohdich F.

J Org Chem. 2005 Nov 11;70(23):9168-74.


Biosynthesis of terpenoids. 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum.

Rohdich F, Eisenreich W, Wungsintaweekul J, Hecht S, Schuhr CA, Bacher A.

Eur J Biochem. 2001 Jun;268(11):3190-7.

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