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Items: 1 to 20 of 105

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Reversing effects of lignans on CCl4-induced hepatic CYP450 down regulation by attenuating oxidative stress.

Xie Y, Hao H, Wang H, Guo C, Kang A, Wang G.

J Ethnopharmacol. 2014 Aug 8;155(1):213-21. doi: 10.1016/j.jep.2014.05.016. Epub 2014 Jun 5.

PMID:
24910408
4.

Integral pharmacokinetics of multiple lignan components in normal, CCl4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers.

Xie Y, Hao H, Kang A, Liang Y, Xie T, Sun S, Dai C, Zheng X, Xie L, Li J, Wang G.

J Ethnopharmacol. 2010 Sep 15;131(2):290-9. doi: 10.1016/j.jep.2010.06.038. Epub 2010 Jun 30.

PMID:
20600750
5.

Multifaceted interaction of the traditional Chinese medicinal herb Schisandra chinensis with cytochrome P450-mediated drug metabolism in rats.

Wang B, Yang S, Hu J, Li Y.

J Ethnopharmacol. 2014 Sep 29;155(3):1473-82. doi: 10.1016/j.jep.2014.07.026. Epub 2014 Aug 1.

PMID:
25091466
6.

[Effects of TJN-101, a lignan compound isolated from Schisandra fruits, on liver fibrosis and on liver regeneration after partial hepatectomy in rats with chronic liver injury induced by CCl4].

Takeda S, Kase Y, Arai I, Ohkura Y, Hasegawa M, Sekiguchi Y, Tatsugi A, Funo S, Aburada M, Hosoya E.

Nihon Yakurigaku Zasshi. 1987 Jul;90(1):51-65. Japanese.

PMID:
2820852
7.

Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.

Jiang Y, Fan X, Wang Y, Tan H, Chen P, Zeng H, Huang M, Bi H.

Chem Biol Interact. 2015 Apr 25;231:83-9. doi: 10.1016/j.cbi.2015.02.022. Epub 2015 Mar 6.

PMID:
25753323
9.

Protective effects of gomisin A isolated from Schisandra chinensis against CCl(4)-induced hepatic and renal injury.

Hwang IS, Kim JE, Lee YJ, Kwak MH, Choi YH, Kang BC, Hong JT, Hwang DY.

Int J Mol Med. 2013 Apr;31(4):888-98. doi: 10.3892/ijmm.2013.1263. Epub 2013 Jan 31.

PMID:
23381504
10.

Chemical-pharmacokinetic-pharmacodynamic fingerprints of Schisandra chinensis alcoholic extract.

Wang BL, Hu JP, Sheng L, Chen H, Li Y.

Yao Xue Xue Bao. 2013 May;48(5):734-40.

PMID:
23888698
11.

Gender-dependent pharmacokinetics of lignans in rats after single and multiple oral administration of Schisandra chinensis extract.

Xu H, Gan J, Liu X, Wu R, Jin Y, Li M, Yuan B.

J Ethnopharmacol. 2013 May 2;147(1):224-31. doi: 10.1016/j.jep.2013.03.008. Epub 2013 Mar 13.

PMID:
23501155
12.

Hepatoprotective effect of Schisandra chinensis (Turcz.) Baill. lignans and its formula with Rubus idaeus on chronic alcohol-induced liver injury in mice.

Wang O, Cheng Q, Liu J, Wang Y, Zhao L, Zhou F, Ji B.

Food Funct. 2014 Nov;5(11):3018-25. doi: 10.1039/c4fo00550c.

PMID:
25255087
15.

[Pharmacokinetics and tissue distribution of Schisandra chinensis extract in mice].

Guan J, Zhu HY, Zhang XR, Zhao Y, Sun DY.

Zhong Yao Cai. 2011 Dec;34(12):1912-5. Chinese.

PMID:
22500430
16.

A pharmacokinetic and pharmacodynamic study of drug-drug interaction between ginsenoside Rg1, ginsenoside Rb1 and schizandrin after intravenous administration to rats.

Zhan S, Guo W, Shao Q, Fan X, Li Z, Cheng Y.

J Ethnopharmacol. 2014 Mar 14;152(2):333-9. doi: 10.1016/j.jep.2014.01.014. Epub 2014 Jan 23.

PMID:
24462784
17.

Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity.

Kim SR, Lee MK, Koo KA, Kim SH, Sung SH, Lee NG, Markelonis GJ, Oh TH, Yang JH, Kim YC.

J Neurosci Res. 2004 May 1;76(3):397-405.

PMID:
15079869
18.

Comparative pharmacokinetics and tissue distribution of schisandrin, deoxyschisandrin and schisandrin B in rats after combining acupuncture and herb medicine (schisandra chinensis).

Wu X, Zhou Y, Yin F, Dai G, Li L, Xu B, Ji D, Sun Y, Mao C, Lu T.

Biomed Chromatogr. 2014 Aug;28(8):1075-83. doi: 10.1002/bmc.3122. Epub 2014 Jan 29.

PMID:
24474333
19.

Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract.

Iwata H, Tezuka Y, Kadota S, Hiratsuka A, Watabe T.

Drug Metab Dispos. 2004 Dec;32(12):1351-8. Epub 2004 Sep 1.

20.

Rapid determination and pharmacokinetics study of lignans in rat plasma after oral administration of Schisandra chinensis extract and pure deoxyschisandrin.

Mao S, Zhang H, Lv L, Zhu Z, Zhao L, Zhang G, Chai Y.

Biomed Chromatogr. 2011 Jul;25(7):808-15. doi: 10.1002/bmc.1520. Epub 2010 Sep 27.

PMID:
20872910

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