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Items: 1 to 20 of 85

1.

Point-mutations related to the loss of batrachotoxin binding abolish the grayanotoxin effect in Na(+) channel isoforms.

Ishii H, Kinoshita E, Kimura T, Yakehiro M, Yamaoka K, Imoto K, Mori Y, Seyama I.

Jpn J Physiol. 1999 Oct;49(5):457-61.

PMID:
10603430
2.

On site of action of grayanotoxin in domain 4 segment 6 of rat skeletal muscle sodium channel.

Kimura T, Kinoshita E, Yamaoka K, Yuki T, Yakehiro M, Seyama I.

FEBS Lett. 2000 Jan 7;465(1):18-22.

3.

Local anesthetic block of batrachotoxin-resistant muscle Na+ channels.

Wang GK, Quan C, Wang SY.

Mol Pharmacol. 1998 Aug;54(2):389-96.

4.

Novel site on sodium channel alpha-subunit responsible for the differential sensitivity of grayanotoxin in skeletal and cardiac muscle.

Kimura T, Yamaoka K, Kinoshita E, Maejima H, Yuki T, Yakehiro M, Seyama I.

Mol Pharmacol. 2001 Oct;60(4):865-72.

5.

Disparate role of Na(+) channel D2-S6 residues in batrachotoxin and local anesthetic action.

Wang SY, Barile M, Wang GK.

Mol Pharmacol. 2001 May;59(5):1100-7.

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7.

Modification of wild-type and batrachotoxin-resistant muscle mu1 Na+ channels by veratridine.

Wang GK, Quan C, Seaver M, Wang SY.

Pflugers Arch. 2000 Apr;439(6):705-13.

PMID:
10784344
8.

Structural determinants for the action of grayanotoxin in D1 S4-S5 and D4 S4-S5 intracellular linkers of sodium channel alpha-subunits.

Maejima H, Kinoshita E, Yuki T, Yakehiro M, Seyama I, Yamaoka K.

Biochem Biophys Res Commun. 2002 Jul 12;295(2):452-7.

PMID:
12150970
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11.

An analysis of the variations in potency of grayanotoxin analogs in modifying frog sodium channels of differing subtypes.

Yakehiro M, Yuki T, Yamaoka K, Furue T, Mori Y, Imoto K, Seyama I.

Mol Pharmacol. 2000 Oct;58(4):692-700.

12.
13.

Irreversible block of cardiac mutant Na+ channels by batrachotoxin.

Wang SY, Tikhonov DB, Mitchell J, Zhorov BS, Wang GK.

Channels (Austin). 2007 May-Jun;1(3):179-88. Epub 2007 May 15.

PMID:
18690024
14.

Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin.

Deschênes I, Neyroud N, DiSilvestre D, Marbán E, Yue DT, Tomaselli GF.

Circ Res. 2002 Mar 8;90(4):E49-57.

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Involvement of batrachotoxin binding sites in ginsenoside-mediated voltage-gated Na+ channel regulation.

Lee JH, Lee BH, Choi SH, Yoon IS, Shin TJ, Pyo MK, Lee SM, Kim HC, Nah SY.

Brain Res. 2008 Apr 8;1203:61-7. doi: 10.1016/j.brainres.2008.01.078. Epub 2008 Feb 12.

PMID:
18321475
19.

State-dependent action of grayanotoxin I on Na(+) channels in frog ventricular myocytes.

Yuki T, Yamaoka K, Yakehiro M, Seyama I.

J Physiol. 2001 Aug 1;534(Pt 3):777-90.

20.

How batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis.

Wang SY, Mitchell J, Tikhonov DB, Zhorov BS, Wang GK.

Mol Pharmacol. 2006 Mar;69(3):788-95. Epub 2005 Dec 14.

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