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Items: 1 to 20 of 104


An Eph receptor regulates integrin activity through R-Ras.

Zou JX, Wang B, Kalo MS, Zisch AH, Pasquale EB, Ruoslahti E.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13813-8.


EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion.

Nakada M, Niska JA, Tran NL, McDonough WS, Berens ME.

Am J Pathol. 2005 Aug;167(2):565-76.


Distinct mechanisms of alpha 5beta 1 integrin activation by Ha-Ras and R-Ras.

Kinashi T, Katagiri K, Watanabe S, Vanhaesebroeck B, Downward J, Takatsu K.

J Biol Chem. 2000 Jul 21;275(29):22590-6.


Calcium/calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation.

Illario M, Cavallo AL, Bayer KU, Di Matola T, Fenzi G, Rossi G, Vitale M.

J Biol Chem. 2003 Nov 14;278(46):45101-8. Epub 2003 Sep 3.


The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon.

Ada-Nguema AS, Xenias H, Hofman JM, Wiggins CH, Sheetz MP, Keely PJ.

J Cell Sci. 2006 Apr 1;119(Pt 7):1307-19. Epub 2006 Mar 14. Erratum in: J Cell Sci. 2006 Oct 15;119(Pt 20):4364. Hofman, Jake M [added]; Wiggins, Chris H [added].


Phosphorylation of focal adhesion kinase at Tyrosine 407 negatively regulates Ras transformation of fibroblasts.

Jeon J, Lee H, Park H, Lee JH, Choi S, Hwang J, Han IO, Oh ES.

Biochem Biophys Res Commun. 2007 Dec 28;364(4):1062-6. Epub 2007 Oct 30.


R-Ras contains a proline-rich site that binds to SH3 domains and is required for integrin activation by R-Ras.

Wang B, Zou JX, Ek-Rylander B, Ruoslahti E.

J Biol Chem. 2000 Feb 18;275(7):5222-7.


R-Ras promotes tumor growth of cervical epithelial cells.

Rincón-Arano H, Rosales R, Mora N, Rodriguez-Castañeda A, Rosales C.

Cancer. 2003 Feb 1;97(3):575-85.


Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells.

Bill HM, Knudsen B, Moores SL, Muthuswamy SK, Rao VR, Brugge JS, Miranti CK.

Mol Cell Biol. 2004 Oct;24(19):8586-99.


Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity.

Zou JX, Liu Y, Pasquale EB, Ruoslahti E.

J Biol Chem. 2002 Jan 18;277(3):1824-7. Epub 2001 Oct 26.


In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue.

Kalo MS, Yu HH, Pasquale EB.

J Biol Chem. 2001 Oct 19;276(42):38940-8. Epub 2001 Jul 20.


Laminin-induced signaling in tumor cells: the role of the M(r) 67,000 laminin receptor.

Givant-Horwitz V, Davidson B, Reich R.

Cancer Res. 2004 May 15;64(10):3572-9.


The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytes.

Yoshikawa Y, Satoh T, Tamura T, Wei P, Bilasy SE, Edamatsu H, Aiba A, Katagiri K, Kinashi T, Nakao K, Kataoka T.

Mol Biol Cell. 2007 Aug;18(8):2949-59. Epub 2007 May 30.


Roles of cell-cell adhesion-dependent tyrosine phosphorylation of Gab-1.

Shinohara M, Kodama A, Matozaki T, Fukuhara A, Tachibana K, Nakanishi H, Takai Y.

J Biol Chem. 2001 Jun 1;276(22):18941-6. Epub 2001 Mar 21.


Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells.

Holland SJ, Gale NW, Gish GD, Roth RA, Songyang Z, Cantley LC, Henkemeyer M, Yancopoulos GD, Pawson T.

EMBO J. 1997 Jul 1;16(13):3877-88.


Compensatory modulation of GAP activity in response to oncogenic stimulation.

Trouba KJ, Liao L, Vorce RL.

Cancer Lett. 1996 Dec 3;109(1-2):211-5.


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