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Items: 1 to 20 of 62

1.

PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development.

Huang H, Potter CJ, Tao W, Li DM, Brogiolo W, Hafen E, Sun H, Xu T.

Development. 1999 Dec;126(23):5365-72.

2.

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway.

Goberdhan DC, Paricio N, Goodman EC, Mlodzik M, Wilson C.

Genes Dev. 1999 Dec 15;13(24):3244-58.

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PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.

Paramio JM, Navarro M, Segrelles C, Gómez-Casero E, Jorcano JL.

Oncogene. 1999 Dec 9;18(52):7462-8.

6.

PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.

Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C.

Cancer Res. 1999 Nov 15;59(22):5808-14.

7.

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene.

Gil EB, Malone Link E, Liu LX, Johnson CD, Lees JA.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2925-30.

8.

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells.

Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang X, Yu SX, Davies MA, Khan H, Furui T, Mao M, Zinner R, Hung MC, Steck P, Siminovitch K, Mills GB.

Oncogene. 1999 Nov 25;18(50):7034-45.

10.

The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene.

Li J, Simpson L, Takahashi M, Miliaresis C, Myers MP, Tonks N, Parsons R.

Cancer Res. 1998 Dec 15;58(24):5667-72.

11.

Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27Kip1 into cyclin E/CDK2 complexes.

Cheney IW, Neuteboom ST, Vaillancourt MT, Ramachandra M, Bookstein R.

Cancer Res. 1999 May 15;59(10):2318-23.

12.

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila.

Scanga SE, Ruel L, Binari RC, Snow B, Stambolic V, Bouchard D, Peters M, Calvieri B, Mak TW, Woodgett JR, Manoukian AS.

Oncogene. 2000 Aug 17;19(35):3971-7.

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Alternative splicing of the Drosophila PTEN gene.

Smith A, Smith A, Alrubaie S, Coehlo C, Leevers SJ, Ashworth A.

Biochim Biophys Acta. 1999 Oct 28;1447(2-3):313-7.

PMID:
10542333
15.

PTEN function in mammalian cell size regulation.

Backman S, Stambolic V, Mak T.

Curr Opin Neurobiol. 2002 Oct;12(5):516-22. Review.

PMID:
12367630
16.

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.

Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2110-5.

17.

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway.

Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15587-91.

18.

TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation.

Heymont J, Berenfeld L, Collins J, Kaganovich A, Maynes B, Moulin A, Ratskovskaya I, Poon PP, Johnston GC, Kamenetsky M, DeSilva J, Sun H, Petsko GA, Engebrecht J.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12672-7.

19.

Regulation of the activity of the tumor suppressor PTEN by thioredoxin in Drosophila melanogaster.

Song Z, Saghafi N, Gokhale V, Brabant M, Meuillet EJ.

Exp Cell Res. 2007 Apr 1;313(6):1161-71. Epub 2007 Jan 12.

20.

Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTEN.

Rouault JP, Kuwabara PE, Sinilnikova OM, Duret L, Thierry-Mieg D, Billaud M.

Curr Biol. 1999 Mar 25;9(6):329-32.

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