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Items: 1 to 20 of 252

1.

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7.

Yokouchi M, Kondo T, Houghton A, Bartkiewicz M, Horne WC, Zhang H, Yoshimura A, Baron R.

J Biol Chem. 1999 Oct 29;274(44):31707-12.

2.

The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor.

Lill NL, Douillard P, Awwad RA, Ota S, Lupher ML Jr, Miyake S, Meissner-Lula N, Hsu VW, Band H.

J Biol Chem. 2000 Jan 7;275(1):367-77.

3.

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor.

Waterman H, Levkowitz G, Alroy I, Yarden Y.

J Biol Chem. 1999 Aug 6;274(32):22151-4.

4.

cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors.

Ettenberg SA, Rubinstein YR, Banerjee P, Nau MM, Keane MM, Lipkowitz S.

Mol Cell Biol Res Commun. 1999 Aug;2(2):111-8.

PMID:
10542134
6.

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies.

Longva KE, Blystad FD, Stang E, Larsen AM, Johannessen LE, Madshus IH.

J Cell Biol. 2002 Mar 4;156(5):843-54. Epub 2002 Feb 25.

7.

Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops.

Rubin C, Litvak V, Medvedovsky H, Zwang Y, Lev S, Yarden Y.

Curr Biol. 2003 Feb 18;13(4):297-307.

8.

N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8.

Ito K, Adachi S, Iwakami R, Yasuda H, Muto Y, Seki N, Okano Y.

Eur J Biochem. 2001 May;268(9):2725-32.

9.

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.

Wong ES, Fong CW, Lim J, Yusoff P, Low BC, Langdon WY, Guy GR.

EMBO J. 2002 Sep 16;21(18):4796-808.

10.

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

Courbard JR, Fiore F, Adélaïde J, Borg JP, Birnbaum D, Ollendorff V.

J Biol Chem. 2002 Nov 22;277(47):45267-75. Epub 2002 Sep 10.

12.

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins.

Yokouchi M, Kondo T, Sanjay A, Houghton A, Yoshimura A, Komiya S, Zhang H, Baron R.

J Biol Chem. 2001 Sep 14;276(37):35185-93. Epub 2001 Jul 11.

13.

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase.

Joazeiro CA, Wing SS, Huang H, Leverson JD, Hunter T, Liu YC.

Science. 1999 Oct 8;286(5438):309-12.

14.

Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation.

Kaabeche K, Lemonnier J, Le Mée S, Caverzasio J, Marie PJ.

J Biol Chem. 2004 Aug 27;279(35):36259-67. Epub 2004 Jun 9.

15.

Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation.

Kaabeche K, Guenou H, Bouvard D, Didelot N, Listrat A, Marie PJ.

J Cell Sci. 2005 Mar 15;118(Pt 6):1223-32. Epub 2005 Feb 22.

16.

Ubiquitinylation and proteasome-dependent degradation of the phosphoinositide-specific phospholipase C gamma 1 in A-431 cells.

Evdonin AL, Tsupkina NV, Nikol'skii NN, Medvedeva ND.

Dokl Biol Sci. 2003 Sep-Oct;392:456-7. No abstract available.

PMID:
14650885
17.

c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination.

Taher TE, Tjin EP, Beuling EA, Borst J, Spaargaren M, Pals ST.

J Immunol. 2002 Oct 1;169(7):3793-800.

18.
19.

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.

Levkowitz G, Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I, Lavi S, Iwai K, Reiss Y, Ciechanover A, Lipkowitz S, Yarden Y.

Mol Cell. 1999 Dec;4(6):1029-40.

20.

Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitination.

Alwan HA, van Zoelen EJ, van Leeuwen JE.

J Biol Chem. 2003 Sep 12;278(37):35781-90. Epub 2003 Jun 26.

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