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Sarcomere thin filament regulatory isoforms. Evidence of a dominant effect of slow skeletal troponin I on cardiac contraction.

Metzger JM, Michele DE, Rust EM, Borton AR, Westfall MV.

J Biol Chem. 2003 Apr 11;278(15):13118-23. Epub 2003 Jan 27.


Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing.

Konhilas JP, Irving TC, Wolska BM, Jweied EE, Martin AF, Solaro RJ, de Tombe PP.

J Physiol. 2003 Mar 15;547(Pt 3):951-61. Epub 2003 Jan 24.


I-band titin in cardiac muscle is a three-element molecular spring and is critical for maintaining thin filament structure.

Linke WA, Rudy DE, Centner T, Gautel M, Witt C, Labeit S, Gregorio CC.

J Cell Biol. 1999 Aug 9;146(3):631-44.


Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity.

Jagatheesan G, Rajan S, Ahmed RP, Petrashevskaya N, Boivin G, Arteaga GM, Tae HJ, Liggett SB, Solaro RJ, Wieczorek DF.

J Muscle Res Cell Motil. 2010 Sep;31(3):227-39. doi: 10.1007/s10974-010-9228-3. Epub 2010 Aug 28.


Gene transfer of troponin I isoforms, mutants, and chimeras.

Westfall MV, Metzger JM.

Adv Exp Med Biol. 2003;538:169-74; discussion 174.


Single amino acid substitutions define isoform-specific effects of troponin I on myofilament Ca2+ and pH sensitivity.

Westfall MV, Metzger JM.

J Mol Cell Cardiol. 2007 Aug;43(2):107-18. Epub 2007 May 24.


Troponin I is required for myofibrillogenesis and sarcomere formation in Drosophila flight muscle.

Nongthomba U, Clark S, Cummins M, Ansari M, Stark M, Sparrow JC.

J Cell Sci. 2004 Apr 1;117(Pt 9):1795-805. Epub 2004 Mar 16.


Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells.

Asumda FZ, Chase PB.

Differentiation. 2012 Mar;83(3):106-15. doi: 10.1016/j.diff.2011.10.002. Epub 2011 Nov 15.


Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis.

Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga GM, Solaro RJ, Liggett SB, Wieczorek DF.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H949-58. Epub 2007 Apr 6.


Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin.

Wolska BM, Keller RS, Evans CC, Palmiter KA, Phillips RM, Muthuchamy M, Oehlenschlager J, Wieczorek DF, de Tombe PP, Solaro RJ.

Circ Res. 1999 Apr 16;84(7):745-51.


Myofilament incorporation determines the stoichiometry of troponin I in transgenic expression and the rescue of a null mutation.

Feng HZ, Hossain MM, Huang XP, Jin JP.

Arch Biochem Biophys. 2009 Jul 1;487(1):36-41. doi: 10.1016/ Epub 2009 May 9.


Expression profiles of muscle disease-associated genes and their isoforms during differentiation of cultured human skeletal muscle cells.

Abdul-Hussein S, van der Ven PF, Tajsharghi H.

BMC Musculoskelet Disord. 2012 Dec 29;13:262. doi: 10.1186/1471-2474-13-262.


Divergent regulation of the sarcomere and the cytoskeleton.

Schevzov G, Fath T, Vrhovski B, Vlahovich N, Rajan S, Hook J, Joya JE, Lemckert F, Puttur F, Lin JJ, Hardeman EC, Wieczorek DF, O'Neill GM, Gunning PW.

J Biol Chem. 2008 Jan 4;283(1):275-83. Epub 2007 Oct 18.


Myofilament length dependent activation.

de Tombe PP, Mateja RD, Tachampa K, Ait Mou Y, Farman GP, Irving TC.

J Mol Cell Cardiol. 2010 May;48(5):851-8. doi: 10.1016/j.yjmcc.2009.12.017. Epub 2010 Jan 4. Review.

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