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Items: 1 to 20 of 107

1.

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family.

Wesche H, Gao X, Li X, Kirschning CJ, Stark GR, Cao Z.

J Biol Chem. 1999 Jul 2;274(27):19403-10.

2.

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase.

Li S, Strelow A, Fontana EJ, Wesche H.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5567-72.

3.

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.

Muzio M, Ni J, Feng P, Dixit VM.

Science. 1997 Nov 28;278(5343):1612-5.

4.

Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling.

Kollewe C, Mackensen AC, Neumann D, Knop J, Cao P, Li S, Wesche H, Martin MU.

J Biol Chem. 2004 Feb 13;279(7):5227-36. Epub 2003 Nov 18.

5.

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

Medzhitov R, Preston-Hurlburt P, Kopp E, Stadlen A, Chen C, Ghosh S, Janeway CA Jr.

Mol Cell. 1998 Aug;2(2):253-8.

6.

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor.

Burns K, Clatworthy J, Martin L, Martinon F, Plumpton C, Maschera B, Lewis A, Ray K, Tschopp J, Volpe F.

Nat Cell Biol. 2000 Jun;2(6):346-51.

PMID:
10854325
7.

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA.

Nature. 2001 Sep 6;413(6851):78-83.

PMID:
11544529
8.

Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling.

Takatsuna H, Kato H, Gohda J, Akiyama T, Moriya A, Okamoto Y, Yamagata Y, Otsuka M, Umezawa K, Semba K, Inoue J.

J Biol Chem. 2003 Apr 4;278(14):12144-50. Epub 2003 Feb 3.

9.

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

Zhang FX, Kirschning CJ, Mancinelli R, Xu XP, Jin Y, Faure E, Mantovani A, Rothe M, Muzio M, Arditi M.

J Biol Chem. 1999 Mar 19;274(12):7611-4.

10.

SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms.

Qin J, Qian Y, Yao J, Grace C, Li X.

J Biol Chem. 2005 Jul 1;280(26):25233-41. Epub 2005 May 2.

11.

IRAK: a kinase associated with the interleukin-1 receptor.

Cao Z, Henzel WJ, Gao X.

Science. 1996 Feb 23;271(5252):1128-31.

PMID:
8599092
12.

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.

Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S.

J Exp Med. 2005 Mar 21;201(6):915-23. Epub 2005 Mar 14.

13.
15.

Signaling events induced by lipopolysaccharide-activated toll-like receptor 2.

Yang RB, Mark MR, Gurney AL, Godowski PJ.

J Immunol. 1999 Jul 15;163(2):639-43.

16.

The Drosophila proteins Pelle and Tube induce JNK/AP-1 activity in mammalian cells.

Bacher S, Grosshans J, Dröge W, Schmitz ML.

FEBS Lett. 2001 May 25;497(2-3):153-8.

17.

Modulation of tumor necrosis factor and interleukin-1-dependent NF-kappaB activity by mPLK/IRAK.

Vig E, Green M, Liu Y, Donner DB, Mukaida N, Goebl MG, Harrington MA.

J Biol Chem. 1999 May 7;274(19):13077-84.

18.

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4.

Suzuki N, Suzuki S, Duncan GS, Millar DG, Wada T, Mirtsos C, Takada H, Wakeham A, Itie A, Li S, Penninger JM, Wesche H, Ohashi PS, Mak TW, Yeh WC.

Nature. 2002 Apr 18;416(6882):750-6. Epub 2002 Mar 31.

PMID:
11923871
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