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Items: 1 to 20 of 86

1.

Mitochondrial DNA 4977 bp deletion and OH8dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients.

Lezza AM, Mecocci P, Cormio A, Beal MF, Cherubini A, Cantatore P, Senin U, Gadaleta MN.

FASEB J. 1999 Jun;13(9):1083-8.

PMID:
10336891
2.

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease.

Mecocci P, MacGarvey U, Beal MF.

Ann Neurol. 1994 Nov;36(5):747-51.

PMID:
7979220
3.

Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease.

de la Monte SM, Luong T, Neely TR, Robinson D, Wands JR.

Lab Invest. 2000 Aug;80(8):1323-35.

PMID:
10950123
4.

Marked changes in mitochondrial DNA deletion levels in Alzheimer brains.

Corral-Debrinski M, Horton T, Lott MT, Shoffner JM, McKee AC, Beal MF, Graham BH, Wallace DC.

Genomics. 1994 Sep 15;23(2):471-6.

PMID:
7835898
5.

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

Mecocci P, MacGarvey U, Kaufman AE, Koontz D, Shoffner JM, Wallace DC, Beal MF.

Ann Neurol. 1993 Oct;34(4):609-16.

PMID:
8215249
6.

Decreased cytochrome-c oxidase activity and lack of age-related accumulation of mitochondrial DNA deletions in the brains of schizophrenics.

Cavelier L, Jazin EE, Eriksson I, Prince J, Båve U, Oreland L, Gyllensten U.

Genomics. 1995 Sep 1;29(1):217-24.

PMID:
8530074
7.

Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex.

Polidori MC, Mecocci P, Browne SE, Senin U, Beal MF.

Neurosci Lett. 1999 Sep 3;272(1):53-6.

PMID:
10507541
8.

A mitochondrial DNA deletion in normally aging and in Alzheimer brain tissue.

Blanchard BJ, Park T, Fripp WJ, Lerman LS, Ingram VM.

Neuroreport. 1993 Jun;4(6):799-802.

PMID:
8347829
9.

Is mitochondrial DNA depletion involved in Alzheimer's disease?

Rodríguez-Santiago B, Casademont J, Nunes V.

Eur J Hum Genet. 2001 Apr;9(4):279-85.

10.

8OHdG levels in brain do not indicate oxidative DNA damage in Alzheimer's disease.

Te Koppele JM, Lucassen PJ, Sakkee AN, Van Asten JG, Ravid R, Swaab DF, Van Bezooijen CF.

Neurobiol Aging. 1996 Nov-Dec;17(6):819-26.

PMID:
9363791
11.

Detection of mtDNA with 4977 bp deletion in blood cells and atherosclerotic lesions of patients with coronary artery disease.

Botto N, Berti S, Manfredi S, Al-Jabri A, Federici C, Clerico A, Ciofini E, Biagini A, Andreassi MG.

Mutat Res. 2005 Feb 15;570(1):81-8.

PMID:
15680405
12.

Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts.

Hayakawa M, Hattori K, Sugiyama S, Ozawa T.

Biochem Biophys Res Commun. 1992 Dec 15;189(2):979-85.

PMID:
1472070
13.

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain.

Lin MT, Simon DK, Ahn CH, Kim LM, Beal MF.

Hum Mol Genet. 2002 Jan 15;11(2):133-45.

PMID:
11809722
14.

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age.

Corral-Debrinski M, Horton T, Lott MT, Shoffner JM, Beal MF, Wallace DC.

Nat Genet. 1992 Dec;2(4):324-9.

PMID:
1303288
15.

Oxidative damage to mitochondrial DNA and its relationship to diabetic complications.

Suzuki S, Hinokio Y, Komatu K, Ohtomo M, Onoda M, Hirai S, Hirai M, Hirai A, Chiba M, Kasuga S, Akai H, Toyota T.

Diabetes Res Clin Pract. 1999 Sep;45(2-3):161-8.

PMID:
10588369
16.

Mitochondrial genomic contribution to mitochondrial dysfunction in Alzheimer's disease.

Onyango I, Khan S, Miller B, Swerdlow R, Trimmer P, Bennett P Jr.

J Alzheimers Dis. 2006 Jul;9(2):183-93. Review.

PMID:
16873965
17.

The frequency of point mutations in mitochondrial DNA is elevated in the Alzheimer's brain.

Chang SW, Zhang D, Chung HD, Zassenhaus HP.

Biochem Biophys Res Commun. 2000 Jun 24;273(1):203-8.

PMID:
10873587
18.
19.

Functional integrity of mitochondrial genomes in human platelets and autopsied brain tissues from elderly patients with Alzheimer's disease.

Ito S, Ohta S, Nishimaki K, Kagawa Y, Soma R, Kuno SY, Komatsuzaki Y, Mizusawa H, Hayashi J.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2099-103.

20.

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease.

Wang J, Xiong S, Xie C, Markesbery WR, Lovell MA.

J Neurochem. 2005 May;93(4):953-62.

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