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Items: 1 to 20 of 172

1.

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

Abriel H, Loffing J, Rebhun JF, Pratt JH, Schild L, Horisberger JD, Rotin D, Staub O.

J Clin Invest. 1999 Mar;103(5):667-73.

2.

Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome.

Goulet CC, Volk KA, Adams CM, Prince LS, Stokes JB, Snyder PM.

J Biol Chem. 1998 Nov 6;273(45):30012-7.

3.

Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage.

Knight KK, Olson DR, Zhou R, Snyder PM.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2805-8. Epub 2006 Feb 13.

4.

Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination.

Staub O, Abriel H, Plant P, Ishikawa T, Kanelis V, Saleki R, Horisberger JD, Schild L, Rotin D.

Kidney Int. 2000 Mar;57(3):809-15. Review.

5.

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

Staub O, Dho S, Henry P, Correa J, Ishikawa T, McGlade J, Rotin D.

EMBO J. 1996 May 15;15(10):2371-80.

6.

Liddle's syndrome: a novel mouse Nedd4 isoform regulates the activity of the epithelial Na(+) channel.

Kamynina E, Debonneville C, Hirt RP, Staub O.

Kidney Int. 2001 Aug;60(2):466-71. Review.

7.

Cystic fibrosis transmembrane conductance regulator inhibits epithelial Na+ channels carrying Liddle's syndrome mutations.

Hopf A, Schreiber R, Mall M, Greger R, Kunzelmann K.

J Biol Chem. 1999 May 14;274(20):13894-9.

8.

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.

Kamynina E, Debonneville C, Bens M, Vandewalle A, Staub O.

FASEB J. 2001 Jan;15(1):204-214.

PMID:
11149908
9.
10.

Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein.

Konstas AA, Shearwin-Whyatt LM, Fotia AB, Degger B, Riccardi D, Cook DI, Korbmacher C, Kumar S.

J Biol Chem. 2002 Aug 16;277(33):29406-16. Epub 2002 Jun 5.

11.

A naturally occurring human Nedd4-2 variant displays impaired ENaC regulation in Xenopus laevis oocytes.

Fouladkou F, Alikhani-Koopaei R, Vogt B, Flores SY, Malbert-Colas L, Lecomte MC, Loffing J, Frey FJ, Frey BM, Staub O.

Am J Physiol Renal Physiol. 2004 Sep;287(3):F550-61. Epub 2004 May 12.

12.

Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel.

McDonald FJ, Western AH, McNeil JD, Thomas BC, Olson DR, Snyder PM.

Am J Physiol Renal Physiol. 2002 Sep;283(3):F431-6.

13.

The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels.

Fotia AB, Dinudom A, Shearwin KE, Koch JP, Korbmacher C, Cook DI, Kumar S.

FASEB J. 2003 Jan;17(1):70-2. Epub 2002 Nov 1.

PMID:
12424229
14.

Multiple WW domains, but not the C2 domain, are required for inhibition of the epithelial Na+ channel by human Nedd4.

Snyder PM, Olson DR, McDonald FJ, Bucher DB.

J Biol Chem. 2001 Jul 27;276(30):28321-6. Epub 2001 May 18.

15.

Liddle's syndrome associated with a point mutation in the extracellular domain of the epithelial sodium channel gamma subunit.

Hiltunen TP, Hannila-Handelberg T, Petäjäniemi N, Kantola I, Tikkanen I, Virtamo J, Gautschi I, Schild L, Kontula K.

J Hypertens. 2002 Dec;20(12):2383-90.

PMID:
12473862
16.

Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+.

Dinudom A, Harvey KF, Komwatana P, Young JA, Kumar S, Cook DI.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7169-73.

17.

Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel.

Henry PC, Kanelis V, O'Brien MC, Kim B, Gautschi I, Forman-Kay J, Schild L, Rotin D.

J Biol Chem. 2003 May 30;278(22):20019-28. Epub 2003 Mar 22.

18.

Relative contribution of Nedd4 and Nedd4-2 to ENaC regulation in epithelia determined by RNA interference.

Snyder PM, Steines JC, Olson DR.

J Biol Chem. 2004 Feb 6;279(6):5042-6. Epub 2003 Nov 26.

19.

Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.

Auberson M, Hoffmann-Pochon N, Vandewalle A, Kellenberger S, Schild L.

Am J Physiol Renal Physiol. 2003 Sep;285(3):F459-71. Epub 2003 May 20.

20.

Immunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC).

Staub O, Yeger H, Plant PJ, Kim H, Ernst SA, Rotin D.

Am J Physiol. 1997 Jun;272(6 Pt 1):C1871-80.

PMID:
9227416

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