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Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport function.

Prasad PD, Wang H, Huang W, Kekuda R, Rajan DP, Leibach FH, Ganapathy V.

Biochem Biophys Res Commun. 1999 Feb 16;255(2):283-8.


Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98).

Kanai Y, Segawa H, Miyamoto Ki, Uchino H, Takeda E, Endou H.

J Biol Chem. 1998 Sep 11;273(37):23629-32.


Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria.

Rajan DP, Kekuda R, Huang W, Wang H, Devoe LD, Leibach FH, Prasad PD, Ganapathy V.

J Biol Chem. 1999 Oct 8;274(41):29005-10.


Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity.

Segawa H, Fukasawa Y, Miyamoto K, Takeda E, Endou H, Kanai Y.

J Biol Chem. 1999 Jul 9;274(28):19745-51.


Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids.

Pineda M, Fernández E, Torrents D, Estévez R, López C, Camps M, Lloberas J, Zorzano A, Palacín M.

J Biol Chem. 1999 Jul 9;274(28):19738-44.


Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.

Yanagida O, Kanai Y, Chairoungdua A, Kim DK, Segawa H, Nii T, Cha SH, Matsuo H, Fukushima J, Fukasawa Y, Tani Y, Taketani Y, Uchino H, Kim JY, Inatomi J, Okayasu I, Miyamoto K, Takeda E, Goya T, Endou H.

Biochim Biophys Acta. 2001 Oct 1;1514(2):291-302.


Transport properties of a system y+L neutral and basic amino acid transporter. Insights into the mechanisms of substrate recognition.

Kanai Y, Fukasawa Y, Cha SH, Segawa H, Chairoungdua A, Kim DK, Matsuo H, Kim JY, Miyamoto K, Takeda E, Endou H.

J Biol Chem. 2000 Jul 7;275(27):20787-93.


Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta.

Wang H, Huang W, Sugawara M, Devoe LD, Leibach FH, Prasad PD, Ganapathy V.

Biochem Biophys Res Commun. 2000 Jul 14;273(3):1175-9.


The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier.

Kageyama T, Nakamura M, Matsuo A, Yamasaki Y, Takakura Y, Hashida M, Kanai Y, Naito M, Tsuruo T, Minato N, Shimohama S.

Brain Res. 2000 Oct 6;879(1-2):115-21.


Expression cloning of a Na(+)-independent neutral amino acid transporter from rat kidney.

Tate SS, Yan N, Udenfriend S.

Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):1-5.


Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain.

Chairoungdua A, Kanai Y, Matsuo H, Inatomi J, Kim DK, Endou H.

J Biol Chem. 2001 Dec 28;276(52):49390-9. Epub 2001 Oct 8.


Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.

Shafqat S, Tamarappoo BK, Kilberg MS, Puranam RS, McNamara JO, Guadaño-Ferraz A, Fremeau RT Jr.

J Biol Chem. 1993 Jul 25;268(21):15351-5.


Molecular and functional characterization of intestinal Na(+)-dependent neutral amino acid transporter B0.

Kekuda R, Torres-Zamorano V, Fei YJ, Prasad PD, Li HW, Mader LD, Leibach FH, Ganapathy V.

Am J Physiol. 1997 Jun;272(6 Pt 1):G1463-72.


4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer.

Nakamura E, Sato M, Yang H, Miyagawa F, Harasaki M, Tomita K, Matsuoka S, Noma A, Iwai K, Minato N.

J Biol Chem. 1999 Jan 29;274(5):3009-16.

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