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Bmp4 is required for the generation of primordial germ cells in the mouse embryo.

Lawson KA, Dunn NR, Roelen BA, Zeinstra LM, Davis AM, Wright CV, Korving JP, Hogan BL.

Genes Dev. 1999 Feb 15;13(4):424-36.


Requirement of Bmp8b for the generation of primordial germ cells in the mouse.

Ying Y, Liu XM, Marble A, Lawson KA, Zhao GQ.

Mol Endocrinol. 2000 Jul;14(7):1053-63.


Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways.

Ying Y, Qi X, Zhao GQ.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7858-62. Epub 2001 Jun 26.


Induction of primordial germ cells from pluripotent epiblast.

Ying Y, Qi X, Zhao GQ.

ScientificWorldJournal. 2002 Mar 26;2:801-10. Review.


BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo.

de Sousa Lopes SM, Roelen BA, Monteiro RM, Emmens R, Lin HY, Li E, Lawson KA, Mummery CL.

Genes Dev. 2004 Aug 1;18(15):1838-49.


SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast.

Hayashi K, Kobayashi T, Umino T, Goitsuka R, Matsui Y, Kitamura D.

Mech Dev. 2002 Oct;118(1-2):99-109.


Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation.

Tremblay KD, Dunn NR, Robertson EJ.

Development. 2001 Sep;128(18):3609-21.


Steel factor controls primordial germ cell survival and motility from the time of their specification in the allantois, and provides a continuous niche throughout their migration.

Gu Y, Runyan C, Shoemaker A, Surani A, Wylie C.

Development. 2009 Apr;136(8):1295-303. doi: 10.1242/dev.030619. Epub 2009 Mar 11.


Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation.

Valdez Magaña G, Rodríguez A, Zhang H, Webb R, Alberio R.

Dev Biol. 2014 Mar 1;387(1):15-27. doi: 10.1016/j.ydbio.2014.01.008. Epub 2014 Jan 18.


BMP signaling regulates PGC numbers and motility in organ culture.

Dudley BM, Runyan C, Takeuchi Y, Schaible K, Molyneaux K.

Mech Dev. 2007 Jan;124(1):68-77. Epub 2006 Sep 30.


Cdx2 contributes to the expansion of the early primordial germ cell population in the mouse.

Bialecka M, Young T, Chuva de Sousa Lopes S, ten Berge D, Sanders A, Beck F, Deschamps J.

Dev Biol. 2012 Nov 15;371(2):227-34. doi: 10.1016/j.ydbio.2012.08.018. Epub 2012 Aug 30.


Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos.

Chatfield J, O'Reilly MA, Bachvarova RF, Ferjentsik Z, Redwood C, Walmsley M, Patient R, Loose M, Johnson AD.

Development. 2014 Jun;141(12):2429-40. doi: 10.1242/dev.105346.


Clonal analysis of the origin of primordial germ cells in the mouse.

Lawson KA, Hage WJ.

Ciba Found Symp. 1994;182:68-84; discussion 84-91. Review.


The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo.

Gu Z, Reynolds EM, Song J, Lei H, Feijen A, Yu L, He W, MacLaughlin DT, van den Eijnden-van Raaij J, Donahoe PK, Li E.

Development. 1999 Jun;126(11):2551-61.

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