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Items: 1 to 20 of 102

1.

TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury.

Zhang DM, Zhang T, Wang MM, Wang XX, Qin YY, Wu J, Han R, Sheng R, Wang Y, Chen Z, Han F, Ding Y, Li M, Qin ZH.

Free Radic Biol Med. 2019 Jun;137:13-23. doi: 10.1016/j.freeradbiomed.2019.04.002. Epub 2019 Apr 9.

PMID:
30978385
2.

TIGAR inhibits ischemia/reperfusion-induced inflammatory response of astrocytes.

Chen J, Zhang DM, Feng X, Wang J, Qin YY, Zhang T, Huang Q, Sheng R, Chen Z, Li M, Qin ZH.

Neuropharmacology. 2018 Mar 15;131:377-388. doi: 10.1016/j.neuropharm.2018.01.012. Epub 2018 Jan 10.

PMID:
29331305
3.

A TIGAR-regulated metabolic pathway is critical for protection of brain ischemia.

Li M, Sun M, Cao L, Gu JH, Ge J, Chen J, Han R, Qin YY, Zhou ZP, Ding Y, Qin ZH.

J Neurosci. 2014 May 28;34(22):7458-71. doi: 10.1523/JNEUROSCI.4655-13.2014.

4.

TIGAR regulates glycolysis in ischemic kidney proximal tubules.

Kim J, Devalaraja-Narashimha K, Padanilam BJ.

Am J Physiol Renal Physiol. 2015 Feb 15;308(4):F298-308. doi: 10.1152/ajprenal.00459.2014. Epub 2014 Dec 10.

5.
6.

LncRNA SNHG12 as a potent autophagy inducer exerts neuroprotective effects against cerebral ischemia/reperfusion injury.

Yao X, Yao R, Huang F, Yi J.

Biochem Biophys Res Commun. 2019 May 2. pii: S0006-291X(19)30809-5. doi: 10.1016/j.bbrc.2019.04.158. [Epub ahead of print]

PMID:
31056262
7.

Endogenous level of TIGAR in brain is associated with vulnerability of neurons to ischemic injury.

Cao L, Chen J, Li M, Qin YY, Sun M, Sheng R, Han F, Wang G, Qin ZH.

Neurosci Bull. 2015 Oct;31(5):527-40. doi: 10.1007/s12264-015-1538-4. Epub 2015 Jul 28.

8.

Ischemia/reperfusion-induced upregulation of TIGAR in brain is mediated by SP1 and modulated by ROS and hormones involved in glucose metabolism.

Sun M, Li M, Huang Q, Han F, Gu JH, Xie J, Han R, Qin ZH, Zhou Z.

Neurochem Int. 2015 Jan;80:99-109. doi: 10.1016/j.neuint.2014.09.006. Epub 2014 Nov 4.

PMID:
25445985
9.

G6PD plays a neuroprotective role in brain ischemia through promoting pentose phosphate pathway.

Cao L, Zhang D, Chen J, Qin YY, Sheng R, Feng X, Chen Z, Ding Y, Li M, Qin ZH.

Free Radic Biol Med. 2017 Nov;112:433-444. doi: 10.1016/j.freeradbiomed.2017.08.011. Epub 2017 Aug 18.

PMID:
28823591
10.

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia.

Wang P, Guan YF, Du H, Zhai QW, Su DF, Miao CY.

Autophagy. 2012 Jan;8(1):77-87. doi: 10.4161/auto.8.1.18274. Epub 2012 Jan 1.

PMID:
22113203
11.
12.

TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells.

Li B, Wang Z, Xie JM, Wang G, Qian LQ, Guan XM, Shen XP, Qin ZH, Shen GH, Li XQ, Gao QG.

Acta Pharmacol Sin. 2019 Jan;40(1):111-121. doi: 10.1038/s41401-018-0001-2. Epub 2018 May 16.

PMID:
29769743
13.

Evaluation of the protective potential of brain microvascular endothelial cell autophagy on blood-brain barrier integrity during experimental cerebral ischemia-reperfusion injury.

Li H, Gao A, Feng D, Wang Y, Zhang L, Cui Y, Li B, Wang Z, Chen G.

Transl Stroke Res. 2014 Oct;5(5):618-26. doi: 10.1007/s12975-014-0354-x. Epub 2014 Jul 30.

PMID:
25070048
14.

Propofol inhibited autophagy through Ca2+/CaMKKβ/AMPK/mTOR pathway in OGD/R-induced neuron injury.

Sun B, Ou H, Ren F, Huan Y, Zhong T, Gao M, Cai H.

Mol Med. 2018 Nov 23;24(1):58. doi: 10.1186/s10020-018-0054-1.

15.

Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury.

He G, Xu W, Tong L, Li S, Su S, Tan X, Li C.

Apoptosis. 2016 Apr;21(4):390-403. doi: 10.1007/s10495-016-1213-x.

PMID:
26882903
16.

cPKCγ-Modulated Autophagy in Neurons Alleviates Ischemic Injury in Brain of Mice with Ischemic Stroke Through Akt-mTOR Pathway.

Wei H, Li Y, Han S, Liu S, Zhang N, Zhao L, Li S, Li J.

Transl Stroke Res. 2016 Dec;7(6):497-511. Epub 2016 Aug 10.

PMID:
27510769
17.

Urolithin A-activated autophagy but not mitophagy protects against ischemic neuronal injury by inhibiting ER stress in vitro and in vivo.

Ahsan A, Zheng YR, Wu XL, Tang WD, Liu MR, Ma SJ, Jiang L, Hu WW, Zhang XN, Chen Z.

CNS Neurosci Ther. 2019 Apr 11. doi: 10.1111/cns.13136. [Epub ahead of print]

PMID:
30972969
18.

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance.

Zhang X, Yan H, Yuan Y, Gao J, Shen Z, Cheng Y, Shen Y, Wang RR, Wang X, Hu WW, Wang G, Chen Z.

Autophagy. 2013 Sep;9(9):1321-33. doi: 10.4161/auto.25132. Epub 2013 Jun 12. Erratum in: Autophagy. 2019 Jun;15(6):1124.

PMID:
23800795
19.

Poloxamer 188 Attenuates Cerebral Hypoxia/Ischemia Injury in Parallel with Preventing Mitochondrial Membrane Permeabilization and Autophagic Activation.

Luo C, Li Q, Gao Y, Shen X, Ma L, Wu Q, Wang Z, Zhang M, Zhao Z, Chen X, Tao L.

J Mol Neurosci. 2015 Aug;56(4):988-998. doi: 10.1007/s12031-015-0568-8. Epub 2015 May 13.

PMID:
25966641
20.

p53 inhibition provides a pivotal protective effect against ischemia-reperfusion injury in vitro via mTOR signaling.

Li X, Gu S, Ling Y, Shen C, Cao X, Xie R.

Brain Res. 2015 Apr 24;1605:31-8. doi: 10.1016/j.brainres.2015.02.009. Epub 2015 Feb 12.

PMID:
25681550

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