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Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.

Cao Y, Ding W, Zhang J, Gao Q, Yang H, Cao W, Wang Z, Fang L, Du R.

J Proteome Res. 2019 Mar 29. doi: 10.1021/acs.jproteome.8b00921. [Epub ahead of print]


DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma.

Liu H, Dong H, Robertson K, Liu C.

Am J Pathol. 2011 Feb;178(2):652-61. doi: 10.1016/j.ajpath.2010.10.023.


Reveal the molecular signatures of hepatocellular carcinoma with different sizes by iTRAQ based quantitative proteomics.

Wang Y, Liu H, Liang D, Huang Y, Zeng Y, Xing X, Xia J, Lin M, Han X, Liao N, Liu X, Liu J.

J Proteomics. 2017 Jan 6;150:230-241. doi: 10.1016/j.jprot.2016.09.008. Epub 2016 Sep 28.


Long noncoding RNA CPS1-IT1 suppresses the metastasis of hepatocellular carcinoma by regulating HIF-1α activity and inhibiting epithelial-mesenchymal transition.

Wang TH, Yu CC, Lin YS, Chen TC, Yeh CT, Liang KH, Shieh TM, Chen CY, Hsueh C.

Oncotarget. 2016 Jul 12;7(28):43588-43603. doi: 10.18632/oncotarget.9635.


Calreticulin down-regulation inhibits the cell growth, invasion and cell cycle progression of human hepatocellular carcinoma cells.

Feng R, Ye J, Zhou C, Qi L, Fu Z, Yan B, Liang Z, Li R, Zhai W.

Diagn Pathol. 2015 Aug 27;10:149. doi: 10.1186/s13000-015-0382-1.


Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues.

Sun W, Xing B, Sun Y, Du X, Lu M, Hao C, Lu Z, Mi W, Wu S, Wei H, Gao X, Zhu Y, Jiang Y, Qian X, He F.

Mol Cell Proteomics. 2007 Oct;6(10):1798-808. Epub 2007 Jul 12.


Identifying hub genes and dysregulated pathways in hepatocellular carcinoma.

Jin B, Wang W, Du G, Huang GZ, Han LT, Tang ZY, Fan DG, Li J, Zhang SZ.

Eur Rev Med Pharmacol Sci. 2015 Feb;19(4):592-601.


GNAI3 inhibits tumor cell migration and invasion and is post-transcriptionally regulated by miR-222 in hepatocellular carcinoma.

Zhang Y, Yao J, Huan L, Lian J, Bao C, Li Y, Ge C, Li J, Yao M, Liang L, He X.

Cancer Lett. 2015 Jan 28;356(2 Pt B):978-84. doi: 10.1016/j.canlet.2014.11.013. Epub 2014 Nov 13.


Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours.

Nwosu ZC, Battello N, Rothley M, Piorońska W, Sitek B, Ebert MP, Hofmann U, Sleeman J, Wölfl S, Meyer C, Megger DA, Dooley S.

J Exp Clin Cancer Res. 2018 Sep 3;37(1):211. doi: 10.1186/s13046-018-0872-6. Erratum in: J Exp Clin Cancer Res. 2018 Nov 2;37(1):267.


RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis.

Gan WJ, Wang JR, Zhu XL, He XS, Guo PD, Zhang S, Li XM, Li JM, Wu H.

J Exp Clin Cancer Res. 2016 Oct 19;35(1):164.


Quantitative proteomic analysis identified paraoxonase 1 as a novel serum biomarker for microvascular invasion in hepatocellular carcinoma.

Huang C, Wang Y, Liu S, Ding G, Liu W, Zhou J, Kuang M, Ji Y, Kondo T, Fan J.

J Proteome Res. 2013 Apr 5;12(4):1838-46. doi: 10.1021/pr3011815. Epub 2013 Mar 5.


The Oncogenic Role of ARG1 in Progression and Metastasis of Hepatocellular Carcinoma.

You J, Chen W, Chen J, Zheng Q, Dong J, Zhu Y.

Biomed Res Int. 2018 Sep 18;2018:2109865. doi: 10.1155/2018/2109865. eCollection 2018.


Predictive value of tumor markers in patients with recurrent hepatocellular carcinoma in different vascular invasion pattern.

Gao F, Zhu HK, Zhu YB, Shan QN, Ling Q, Wei XY, Xie HY, Zhou L, Xu X, Zheng SS.

Hepatobiliary Pancreat Dis Int. 2016 Aug;15(4):371-7.


Vascular invasion in hepatocellular carcinoma: prevalence, determinants and prognostic impact.

Lee YH, Hsu CY, Huang YH, Hsia CY, Chiou YY, Su CW, Lin HC, Huo TI.

J Clin Gastroenterol. 2014 Sep;48(8):734-41. doi: 10.1097/MCG.0b013e3182a8a254.


Argininosuccinate synthase 1 suppresses cancer cell invasion by inhibiting STAT3 pathway in hepatocellular carcinoma.

Tao X, Zuo Q, Ruan H, Wang H, Jin H, Cheng Z, Lv Y, Qin W, Wang C.

Acta Biochim Biophys Sin (Shanghai). 2019 Mar 1;51(3):263-276. doi: 10.1093/abbs/gmz005.


Two Nomograms to Select Hepatocellular Carcinoma Patients with Macroscopic Vascular Invasion for Hepatic Resection.

Jiang Y, Tang H, Wang Z, Sun Y, Meng W, Wang G, Li H, Yi S, Wang G, Yang Y, Chen G.

J Cancer. 2018 Sep 7;9(18):3287-3294. doi: 10.7150/jca.25899. eCollection 2018.


microRNA-520f inhibits hepatocellular carcinoma cell proliferation and invasion by targeting TM4SF1.

Du X, Fan W, Chen Y.

Gene. 2018 May 30;657:30-38. doi: 10.1016/j.gene.2018.03.003. Epub 2018 Mar 2.


Invasion and metastasis-related long noncoding RNA expression profiles in hepatocellular carcinoma.

Gao Y, Chen G, Zeng Y, Zeng J, Lin M, Liu X, Liu J.

Tumour Biol. 2015 Sep;36(10):7409-22. doi: 10.1007/s13277-015-3408-0. Epub 2015 Apr 22.


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