Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98

1.

Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling.

Guo J, Wang Z, Wu J, Liu M, Li M, Sun Y, Huang W, Li Y, Zhang Y, Tang W, Li X, Zhang C, Hong F, Li N, Nie J, Yi F.

Circ Res. 2019 Mar 21. doi: 10.1161/CIRCRESAHA.118.314032. [Epub ahead of print]

PMID:
30894089
2.

Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.

Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F.

Nat Commun. 2017 Sep 4;8(1):413. doi: 10.1038/s41467-017-00498-4.

3.

SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence.

Cardus A, Uryga AK, Walters G, Erusalimsky JD.

Cardiovasc Res. 2013 Mar 1;97(3):571-9. doi: 10.1093/cvr/cvs352. Epub 2012 Dec 1.

4.

SIRT6 protects against endothelial dysfunction and atherosclerosis in mice.

Xu S, Yin M, Koroleva M, Mastrangelo MA, Zhang W, Bai P, Little PJ, Jin ZG.

Aging (Albany NY). 2016 May;8(5):1064-82. doi: 10.18632/aging.100975.

5.

Endothelial Gata5 transcription factor regulates blood pressure.

Messaoudi S, He Y, Gutsol A, Wight A, Hébert RL, Vilmundarson RO, Makrigiannis AP, Chalmers J, Hamet P, Tremblay J, McPherson R, Stewart AF, Touyz RM, Nemer M.

Nat Commun. 2015 Nov 30;6:8835. doi: 10.1038/ncomms9835.

6.

Epigenetic control of early neurodegenerative events in diabetic retinopathy by the histone deacetylase SIRT6.

Zorrilla-Zubilete MA, Yeste A, Quintana FJ, Toiber D, Mostoslavsky R, Silberman DM.

J Neurochem. 2018 Jan;144(2):128-138. doi: 10.1111/jnc.14243. Epub 2017 Nov 21.

7.

Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence.

Takasaka N, Araya J, Hara H, Ito S, Kobayashi K, Kurita Y, Wakui H, Yoshii Y, Yumino Y, Fujii S, Minagawa S, Tsurushige C, Kojima J, Numata T, Shimizu K, Kawaishi M, Kaneko Y, Kamiya N, Hirano J, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K.

J Immunol. 2014 Feb 1;192(3):958-68. doi: 10.4049/jimmunol.1302341. Epub 2013 Dec 23.

8.

Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling.

Li Z, Xu K, Zhang N, Amador G, Wang Y, Zhao S, Li L, Qiu Y, Wang Z.

Kidney Int. 2018 Apr;93(4):881-892. doi: 10.1016/j.kint.2017.10.021. Epub 2018 Jan 17.

PMID:
29373150
9.

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.

Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R.

Cell. 2010 Jan 22;140(2):280-93. doi: 10.1016/j.cell.2009.12.041.

10.

SIRT6 protects against hepatic ischemia/reperfusion injury by inhibiting apoptosis and autophagy related cell death.

Zhang S, Jiang S, Wang H, Di W, Deng C, Jin Z, Yi W, Xiao X, Nie Y, Yang Y.

Free Radic Biol Med. 2018 Feb 1;115:18-30. doi: 10.1016/j.freeradbiomed.2017.11.005. Epub 2017 Nov 10.

PMID:
29129519
11.

SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection.

D'Onofrio N, Servillo L, Balestrieri ML.

Antioxid Redox Signal. 2018 Mar 10;28(8):711-732. doi: 10.1089/ars.2017.7178. Epub 2017 Jun 29. Review.

12.

Oxidative stress induces endothelial cell senescence via downregulation of Sirt6.

Liu R, Liu H, Ha Y, Tilton RG, Zhang W.

Biomed Res Int. 2014;2014:902842. doi: 10.1155/2014/902842. Epub 2014 Aug 5.

13.

SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling.

Wang H, Diao D, Shi Z, Zhu X, Gao Y, Gao S, Liu X, Wu Y, Rudolph KL, Liu G, Li T, Ju Z.

Cell Stem Cell. 2016 Apr 7;18(4):495-507. doi: 10.1016/j.stem.2016.03.005.

14.

SIRT6 protects cardiomyocytes against ischemia/reperfusion injury by augmenting FoxO3α-dependent antioxidant defense mechanisms.

Wang XX, Wang XL, Tong MM, Gan L, Chen H, Wu SS, Chen JX, Li RL, Wu Y, Zhang HY, Zhu Y, Li YX, He JH, Wang M, Jiang W.

Basic Res Cardiol. 2016 Mar;111(2):13. doi: 10.1007/s00395-016-0531-z. Epub 2016 Jan 19.

PMID:
26786260
15.
16.

PGC-1α overexpression suppresses blood pressure elevation in DOCA-salt hypertensive mice.

Zhao Q, Zhang J, Wang H.

Biosci Rep. 2015 May 21;35(3). pii: e00217. doi: 10.1042/BSR20150076.

17.

Deletion of sirtuin 6 accelerates endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice.

Liu Z, Wang J, Huang X, Li Z, Liu P.

Transl Res. 2016 Jun;172:18-29.e2. doi: 10.1016/j.trsl.2016.02.005. Epub 2016 Feb 11.

PMID:
26924042
18.

Endothelial dysfunction in DOCA-salt-hypertensive mice: role of neuronal nitric oxide synthase-derived hydrogen peroxide.

Silva GC, Silva JF, Diniz TF, Lemos VS, Cortes SF.

Clin Sci (Lond). 2016 Jun 1;130(11):895-906. doi: 10.1042/CS20160062. Epub 2016 Mar 14.

PMID:
26976926
19.
20.

Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development.

Wu Y, Chen L, Wang Y, Li W, Lin Y, Yu D, Zhang L, Li F, Pan Z.

Sci Rep. 2015 Dec 7;5:17602. doi: 10.1038/srep17602.

Supplemental Content

Support Center