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Items: 1 to 20 of 101

1.

MS-275 induces hepatic FGF21 expression via H3K18ac-mediated CREBH signal.

Zhang Q, Zhu Q, Ruyuan D, Zhou F, Zhang L, Wang S, Zhu K, Xiao W, Libin Z, Su Q.

J Mol Endocrinol. 2019 Mar 1. pii: JME-18-0259.R2. doi: 10.1530/JME-18-0259. [Epub ahead of print]

PMID:
30893641
2.

Hepatic Aryl Hydrocarbon Receptor Attenuates Fibroblast Growth Factor 21 Expression.

Girer NG, Murray IA, Omiecinski CJ, Perdew GH.

J Biol Chem. 2016 Jul 15;291(29):15378-87. doi: 10.1074/jbc.M116.715151. Epub 2016 May 25.

3.

Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21.

Kim H, Mendez R, Zheng Z, Chang L, Cai J, Zhang R, Zhang K.

Endocrinology. 2014 Mar;155(3):769-82. doi: 10.1210/en.2013-1490. Epub 2014 Jan 1.

4.

Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.

Li Y, Wong K, Giles A, Jiang J, Lee JW, Adams AC, Kharitonenkov A, Yang Q, Gao B, Guarente L, Zang M.

Gastroenterology. 2014 Feb;146(2):539-49.e7. doi: 10.1053/j.gastro.2013.10.059. Epub 2013 Nov 1.

5.

Alpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH.

Bae KH, Min AK, Kim JG, Lee IK, Park KG.

Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):212-7. doi: 10.1016/j.bbrc.2014.10.147. Epub 2014 Nov 5.

PMID:
25449271
6.

Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo.

Fisher FM, Estall JL, Adams AC, Antonellis PJ, Bina HA, Flier JS, Kharitonenkov A, Spiegelman BM, Maratos-Flier E.

Endocrinology. 2011 Aug;152(8):2996-3004. doi: 10.1210/en.2011-0281. Epub 2011 Jun 28.

7.

Regulation of energy metabolism by long-chain fatty acids.

Nakamura MT, Yudell BE, Loor JJ.

Prog Lipid Res. 2014 Jan;53:124-44. doi: 10.1016/j.plipres.2013.12.001. Epub 2013 Dec 18. Review.

PMID:
24362249
8.

Lysine Acetylation of CREBH Regulates Fasting-Induced Hepatic Lipid Metabolism.

Kim H, Mendez R, Chen X, Fang D, Zhang K.

Mol Cell Biol. 2015 Dec;35(24):4121-34. doi: 10.1128/MCB.00665-15. Epub 2015 Oct 5.

9.

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.

Kikuchi T, Orihara K, Oikawa F, Han SI, Kuba M, Okuda K, Satoh A, Osaki Y, Takeuchi Y, Aita Y, Matsuzaka T, Iwasaki H, Yatoh S, Sekiya M, Yahagi N, Suzuki H, Sone H, Nakagawa Y, Yamada N, Shimano H.

Mol Metab. 2016 Sep 17;5(11):1092-1102. doi: 10.1016/j.molmet.2016.09.004. eCollection 2016 Nov.

10.

Fibroblast growth factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic peroxisome proliferator-activated receptor γ coactivator-1α-deficient mice.

Fletcher JA, Linden MA, Sheldon RD, Meers GM, Morris EM, Butterfield A, Perfield JW 2nd, Rector RS, Thyfault JP.

Exp Physiol. 2018 Mar 1;103(3):408-418. doi: 10.1113/EP086629. Epub 2018 Jan 16.

11.

Retinoic acid receptor β stimulates hepatic induction of fibroblast growth factor 21 to promote fatty acid oxidation and control whole-body energy homeostasis in mice.

Li Y, Wong K, Walsh K, Gao B, Zang M.

J Biol Chem. 2013 Apr 12;288(15):10490-504. doi: 10.1074/jbc.M112.429852. Epub 2013 Feb 19.

12.

Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice.

Ye D, Wang Y, Li H, Jia W, Man K, Lo CM, Wang Y, Lam KS, Xu A.

Hepatology. 2014 Sep;60(3):977-89. doi: 10.1002/hep.27060. Epub 2014 Jul 25.

PMID:
24590984
13.

Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes.

Chanda D, Kim DK, Li T, Kim YH, Koo SH, Lee CH, Chiang JY, Choi HS.

J Biol Chem. 2011 Aug 12;286(32):27971-9. doi: 10.1074/jbc.M111.224352. Epub 2011 Jun 21.

14.

Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet.

Tanaka N, Takahashi S, Zhang Y, Krausz KW, Smith PB, Patterson AD, Gonzalez FJ.

Biochim Biophys Acta. 2015 Jul;1852(7):1242-52. doi: 10.1016/j.bbadis.2015.02.012. Epub 2015 Feb 28.

15.

Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21.

Cyphert HA, Ge X, Kohan AB, Salati LM, Zhang Y, Hillgartner FB.

J Biol Chem. 2012 Jul 20;287(30):25123-38. doi: 10.1074/jbc.M112.375907. Epub 2012 Jun 1.

16.

CREBH Regulates Systemic Glucose and Lipid Metabolism.

Nakagawa Y, Shimano H.

Int J Mol Sci. 2018 May 8;19(5). pii: E1396. doi: 10.3390/ijms19051396. Review.

17.

Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression.

Min AK, Bae KH, Jung YA, Choi YK, Kim MJ, Kim JH, Jeon JH, Kim JG, Lee IK, Park KG.

Endocrinology. 2014 Aug;155(8):2924-31. doi: 10.1210/en.2013-1758. Epub 2014 Jun 2. Erratum in: Endocrinology. 2015 Jan;156(1):406.

PMID:
24885573
18.

Orphan nuclear receptor Errγ induces C-reactive protein gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH.

Misra J, Chanda D, Kim DK, Cho SR, Koo SH, Lee CH, Back SH, Choi HS.

PLoS One. 2014 Jan 22;9(1):e86342. doi: 10.1371/journal.pone.0086342. eCollection 2014. Erratum in: PLoS One. 2015;10(5):e0125536.

19.

Berberine-induced activation of AMPK increases hepatic FGF21 expression via NUR77.

Zhou F, Bai M, Zhang Y, Zhu Q, Zhang L, Zhang Q, Wang S, Zhu K, Liu Y, Wang X, Zhou L.

Biochem Biophys Res Commun. 2018 Jan 8;495(2):1936-1941. doi: 10.1016/j.bbrc.2017.12.070. Epub 2017 Dec 13.

PMID:
29247651
20.

Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice.

Zhang C, Wang G, Zheng Z, Maddipati KR, Zhang X, Dyson G, Williams P, Duncan SA, Kaufman RJ, Zhang K.

Hepatology. 2012 Apr;55(4):1070-82. doi: 10.1002/hep.24783. Epub 2012 Feb 9.

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