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Items: 1 to 20 of 103

1.

Scutellarin exerts protective effects against atherosclerosis in rats by regulating the Hippo-FOXO3A and PI3K/AKT signaling pathways.

Fu Y, Sun S, Sun H, Peng J, Ma X, Bao L, Ji R, Luo C, Gao C, Zhang X, Jin Y.

J Cell Physiol. 2019 Mar 19. doi: 10.1002/jcp.28446. [Epub ahead of print]

PMID:
30891776
2.

Involvement of PI3K/Akt/FoxO3a and PKA/CREB Signaling Pathways in the Protective Effect of Fluoxetine Against Corticosterone-Induced Cytotoxicity in PC12 Cells.

Zeng B, Li Y, Niu B, Wang X, Cheng Y, Zhou Z, You T, Liu Y, Wang H, Xu J.

J Mol Neurosci. 2016 Aug;59(4):567-78. doi: 10.1007/s12031-016-0779-7. Epub 2016 Jul 13.

PMID:
27412469
3.

Fluid shear stress suppresses TNF-Ī±-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways.

Bin G, Bo Z, Jing W, Jin J, Xiaoyi T, Cong C, Liping A, Jinglin M, Cuifang W, Yonggang C, Yayi X.

Exp Cell Res. 2016 May 1;343(2):208-217. doi: 10.1016/j.yexcr.2016.03.014. Epub 2016 Apr 6.

PMID:
27060196
4.

Hydrogen protects against hyperoxia-induced apoptosis in type II alveolar epithelial cells via activation of PI3K/Akt/Foxo3a signaling pathway.

Wu D, Liang M, Dang H, Fang F, Xu F, Liu C.

Biochem Biophys Res Commun. 2018 Jan 8;495(2):1620-1627. doi: 10.1016/j.bbrc.2017.11.193. Epub 2017 Dec 2.

PMID:
29198702
5.

The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway.

Zeng Z, Wang X, Bhardwaj SK, Zhou X, Little PJ, Quirion R, Srivastava LK, Zheng W.

Mol Neurobiol. 2017 Jul;54(5):3395-3406. doi: 10.1007/s12035-016-9904-4. Epub 2016 May 13.

PMID:
27173157
6.

Attenuation of age-related changes in FOXO3a activity and the PI3K/Akt pathway by short-term feeding of ferulate.

Choi YJ, Kim DH, Lee EK, Kim JM, Ha YM, Kim ND, Jung JH, Choi JS, Yu BP, Chung HY.

Age (Dordr). 2012 Apr;34(2):317-27. doi: 10.1007/s11357-011-9235-3. Epub 2011 Apr 6.

7.

Resveratrol Ameliorates Cardiac Dysfunction by Inhibiting Apoptosis via the PI3K/Akt/FoxO3a Pathway in a Rat Model of Diabetic Cardiomyopathy.

Wu Z, Huang A, Yan J, Liu B, Liu Q, Zhang J, Zhang X, Ou C, Chen M.

J Cardiovasc Pharmacol. 2017 Sep;70(3):184-193. doi: 10.1097/FJC.0000000000000504.

PMID:
28678055
8.

The role of Akt/FoxO3a in the protective effect of venlafaxine against corticosterone-induced cell death in PC12 cells.

Wang H, Zhou X, Huang J, Mu N, Guo Z, Wen Q, Wang R, Chen S, Feng ZP, Zheng W.

Psychopharmacology (Berl). 2013 Jul;228(1):129-41. doi: 10.1007/s00213-013-3017-9. Epub 2013 Mar 15.

PMID:
23494228
9.

Shikonin induces apoptosis of lung cancer cells via activation of FOXO3a/EGR1/SIRT1 signaling antagonized by p300.

Jeung YJ, Kim HG, Ahn J, Lee HJ, Lee SB, Won M, Jung CR, Im JY, Kim BK, Park SK, Son MJ, Chung KS.

Biochim Biophys Acta. 2016 Nov;1863(11):2584-2593. doi: 10.1016/j.bbamcr.2016.07.005. Epub 2016 Jul 21.

10.

Regulation of FOXO3a by brain-derived neurotrophic factor in differentiated human SH-SY5Y neuroblastoma cells.

Zhu W, Bijur GN, Styles NA, Li X.

Brain Res Mol Brain Res. 2004 Jul 5;126(1):45-56.

PMID:
15207915
11.

Scutellarin protects against vascular endothelial dysfunction and prevents atherosclerosis via antioxidation.

Mo J, Yang R, Li F, Zhang X, He B, Zhang Y, Chen P, Shen Z.

Phytomedicine. 2018 Mar 15;42:66-74. doi: 10.1016/j.phymed.2018.03.021. Epub 2018 Mar 14.

PMID:
29655699
12.
13.

Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway.

Xiao Q, Ye Q, Wang W, Xiao J, Fu B, Xia Z, Zhang X, Liu Z, Zeng X.

Mol Med Rep. 2017 Nov;16(5):7520-7526. doi: 10.3892/mmr.2017.7501. Epub 2017 Sep 18.

14.

Anti-microRNA-132 causes sevofluraneā€‘induced neuronal apoptosis via the PI3K/AKT/FOXO3a pathway.

Dong P, Zhang X, Zhao J, Li D, Li L, Yang B.

Int J Mol Med. 2018 Dec;42(6):3238-3246. doi: 10.3892/ijmm.2018.3895. Epub 2018 Sep 25.

15.

Hydrogen sulfide protects H9c2 cardiac cells against doxorubicin-induced cytotoxicity through the PI3K/Akt/FoxO3a pathway.

Liu MH, Zhang Y, He J, Tan TP, Wu SJ, Guo DM, He H, Peng J, Tang ZH, Jiang ZS.

Int J Mol Med. 2016 Jun;37(6):1661-8. doi: 10.3892/ijmm.2016.2563. Epub 2016 Apr 14.

PMID:
27081862
16.

PI3K/Akt/FoxO3a signaling mediates cardioprotection of FGF-2 against hydrogen peroxide-induced apoptosis in H9c2 cells.

Liu MH, Li GH, Peng LJ, Qu SL, Zhang Y, Peng J, Luo XY, Hu HJ, Ren Z, Liu Y, Tang H, Liu LS, Tang ZH, Jiang ZS.

Mol Cell Biochem. 2016 Mar;414(1-2):57-66. doi: 10.1007/s11010-016-2658-5. Epub 2016 Feb 22.

PMID:
26899709
17.

Sodium tanshinone IIA sulfonate protects rat myocardium against ischemia-reperfusion injury via activation of PI3K/Akt/FOXO3A/Bim pathway.

Zhang MQ, Zheng YL, Chen H, Tu JF, Shen Y, Guo JP, Yang XH, Yuan SR, Chen LZ, Chai JJ, Lu JH, Zhai CL.

Acta Pharmacol Sin. 2013 Nov;34(11):1386-96. doi: 10.1038/aps.2013.91. Epub 2013 Sep 30.

19.

Ginsenoside Rg1 protects human umbilical cord blood-derived stromal cells against tert-Butyl hydroperoxide-induced apoptosis through Akt-FoxO3a-Bim signaling pathway.

Liu Y, Yi L, Wang L, Chen L, Chen X, Wang Y.

Mol Cell Biochem. 2016 Oct;421(1-2):75-87. doi: 10.1007/s11010-016-2786-y. Epub 2016 Aug 13.

PMID:
27522666
20.

Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium.

Fujiki K, Inamura H, Matsuoka M.

Arch Toxicol. 2013 Dec;87(12):2119-27. doi: 10.1007/s00204-013-1077-6. Epub 2013 May 15.

PMID:
23673518

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