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An alternative splicing alters the product outcome of a class I terpene synthase in Isodon rubescens.

Jin B, Guo J, Tang J, Tong Y, Ma Y, Chen T, Wang Y, Shen Y, Zhao Y, Lai C, Cui G, Huang L.

Biochem Biophys Res Commun. 2019 Apr 30;512(2):310-313. doi: 10.1016/j.bbrc.2019.03.057. Epub 2019 Mar 16.


Functional Diversification of Kaurene Synthase-Like Genes in Isodon rubescens.

Jin B, Cui G, Guo J, Tang J, Duan L, Lin H, Shen Y, Chen T, Zhang H, Huang L.

Plant Physiol. 2017 Jun;174(2):943-955. doi: 10.1104/pp.17.00202. Epub 2017 Apr 5.


Biosynthesis of the oxygenated diterpene nezukol in the medicinal plant Isodon rubescens is catalyzed by a pair of diterpene synthases.

Pelot KA, Hagelthorn DM, Addison JB, Zerbe P.

PLoS One. 2017 Apr 26;12(4):e0176507. doi: 10.1371/journal.pone.0176507. eCollection 2017.


One amino acid makes the difference: the formation of ent-kaurene and 16α-hydroxy-ent-kaurane by diterpene synthases in poplar.

Irmisch S, Müller AT, Schmidt L, Günther J, Gershenzon J, Köllner TG.

BMC Plant Biol. 2015 Oct 28;15:262. doi: 10.1186/s12870-015-0647-6.


Biochemical characterization of microbial type terpene synthases in two closely related species of hornworts, Anthoceros punctatus and Anthoceros agrestis.

Xiong W, Fu J, Köllner TG, Chen X, Jia Q, Guo H, Qian P, Guo H, Wu G, Chen F.

Phytochemistry. 2018 May;149:116-122. doi: 10.1016/j.phytochem.2018.02.011. Epub 2018 Feb 27.


The terpene synthase gene family in Tripterygium wilfordii harbors a labdane-type diterpene synthase among the monoterpene synthase TPS-b subfamily.

Hansen NL, Heskes AM, Hamberger B, Olsen CE, Hallström BM, Andersen-Ranberg J, Hamberger B.

Plant J. 2017 Feb;89(3):429-441. doi: 10.1111/tpj.13410. Epub 2017 Feb 14.


Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii.

Su P, Guan H, Zhao Y, Tong Y, Xu M, Zhang Y, Hu T, Yang J, Cheng Q, Gao L, Liu Y, Zhou J, Peters RJ, Huang L, Gao W.

Plant J. 2018 Jan;93(1):50-65. doi: 10.1111/tpj.13756. Epub 2017 Dec 2.


A Pair of Residues That Interactively Affect Diterpene Synthase Product Outcome.

Jia M, Zhou K, Tufts S, Schulte S, Peters RJ.

ACS Chem Biol. 2017 Mar 17;12(3):862-867. doi: 10.1021/acschembio.6b01075. Epub 2017 Feb 14.


cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis).

Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R.

Arch Biochem Biophys. 1999 Aug 15;368(2):232-43.


[Cloning and Expression Analysis of Acetyl-CoA C-acetyltransferase Gene in Isodon rubescens].

Zhu YH, Su XH, Dong CM, Chen SQ, Shao YY, Zhang FB.

Zhong Yao Cai. 2016 Jan;39(1):37-41. Chinese.


Diterpene synthases facilitating production of the kaurane skeleton of eriocalyxin B in the medicinal plant Isodon eriocalyx.

Du G, Gong HY, Feng KN, Chen QQ, Yang YL, Fu XL, Lu S, Zeng Y.

Phytochemistry. 2019 Feb;158:96-102. doi: 10.1016/j.phytochem.2018.11.015. Epub 2018 Nov 26.


Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha.

Kumar S, Kempinski C, Zhuang X, Norris A, Mafu S, Zi J, Bell SA, Nybo SE, Kinison SE, Jiang Z, Goklany S, Linscott KB, Chen X, Jia Q, Brown SD, Bowman JL, Babbitt PC, Peters RJ, Chen F, Chappell J.

Plant Cell. 2016 Oct;28(10):2632-2650. Epub 2016 Sep 20.


Enzymatic (13)C labeling and multidimensional NMR analysis of miltiradiene synthesized by bifunctional diterpene cyclase in Selaginella moellendorffii.

Sugai Y, Ueno Y, Hayashi K, Oogami S, Toyomasu T, Matsumoto S, Natsume M, Nozaki H, Kawaide H.

J Biol Chem. 2011 Dec 16;286(50):42840-7. doi: 10.1074/jbc.M111.302703. Epub 2011 Oct 25.


Insights Into the Bifunctional Aphidicolan-16-ß-ol Synthase Through Rapid Biomolecular Modeling Approaches.

Hirte M, Meese N, Mertz M, Fuchs M, Brück TB.

Front Chem. 2018 Apr 10;6:101. doi: 10.3389/fchem.2018.00101. eCollection 2018.


Rubesanolides A and B: diterpenoids from Isodon rubescens.

Zou J, Pan L, Li Q, Zhao J, Pu J, Yao P, Gong N, Lu Y, Kondratyuk TP, Pezzuto JM, Fong HH, Zhang H, Sun H.

Org Lett. 2011 Mar 18;13(6):1406-9. doi: 10.1021/ol200086k. Epub 2011 Feb 18.


Identification of amino acid networks governing catalysis in the closed complex of class I terpene synthases.

Schrepfer P, Buettner A, Goerner C, Hertel M, van Rijn J, Wallrapp F, Eisenreich W, Sieber V, Kourist R, Brück T.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E958-67. doi: 10.1073/pnas.1519680113. Epub 2016 Feb 3.

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