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Ferritin nanocage-based antigen delivery nanoplatforms: epitope engineering for peptide vaccine design.

Wang Z, Xu L, Yu H, Lv P, Lei Z, Zeng Y, Liu G, Cheng T.

Biomater Sci. 2019 Mar 19. doi: 10.1039/c9bm00098d. [Epub ahead of print]


Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics.

Lee NK, Lee EJ, Kim S, Nam GH, Kih M, Hong Y, Jeong C, Yang Y, Byun Y, Kim IS.

J Control Release. 2017 Dec 10;267:172-180. doi: 10.1016/j.jconrel.2017.08.014. Epub 2017 Aug 15.


Ferritin protein cage nanoparticles as versatile antigen delivery nanoplatforms for dendritic cell (DC)-based vaccine development.

Han JA, Kang YJ, Shin C, Ra JS, Shin HH, Hong SY, Do Y, Kang S.

Nanomedicine. 2014 Apr;10(3):561-9. doi: 10.1016/j.nano.2013.11.003. Epub 2013 Nov 18.


Protection against lethal enterovirus 71 challenge in mice by a recombinant vaccine candidate containing a broadly cross-neutralizing epitope within the VP2 EF loop.

Xu L, He D, Li Z, Zheng J, Yang L, Yu M, Yu H, Chen Y, Que Y, Shih JW, Liu G, Zhang J, Zhao Q, Cheng T, Xia N.

Theranostics. 2014 Feb 18;4(5):498-513. doi: 10.7150/thno.7457. eCollection 2014.


Protection against enterovirus 71 with neutralizing epitope incorporation within adenovirus type 3 hexon.

Tian X, Su X, Li X, Li H, Li T, Zhou Z, Zhong T, Zhou R.

PLoS One. 2012;7(7):e41381. doi: 10.1371/journal.pone.0041381. Epub 2012 Jul 27. Erratum in: PLoS One. 2012;7(10). doi:10.1371/annotation/2da932d4-8654-45c8-bf83-7b3b09dbc146.


A new EV71 VP3 epitope in norovirus P particle vector displays neutralizing activity and protection in vivo in mice.

Jiang L, Fan R, Sun S, Fan P, Su W, Zhou Y, Gao F, Xu F, Kong W, Jiang C.

Vaccine. 2015 Nov 27;33(48):6596-603. doi: 10.1016/j.vaccine.2015.10.104. Epub 2015 Oct 31.


Ferritin nanocages: A biological platform for drug delivery, imaging and theranostics in cancer.

Truffi M, Fiandra L, Sorrentino L, Monieri M, Corsi F, Mazzucchelli S.

Pharmacol Res. 2016 May;107:57-65. doi: 10.1016/j.phrs.2016.03.002. Epub 2016 Mar 9. Review.


Hexon-modified recombinant E1-deleted adenoviral vectors as bivalent vaccine carriers for Coxsackievirus A16 and Enterovirus 71.

Zhang C, Yang Y, Chi Y, Yin J, Yan L, Ku Z, Liu Q, Huang Z, Zhou D.

Vaccine. 2015 Sep 22;33(39):5087-94. doi: 10.1016/j.vaccine.2015.08.016. Epub 2015 Aug 19.


Identification and characterization of a cross-neutralization epitope of Enterovirus 71.

Liu CC, Chou AH, Lien SP, Lin HY, Liu SJ, Chang JY, Guo MS, Chow YH, Yang WS, Chang KH, Sia C, Chong P.

Vaccine. 2011 Jun 10;29(26):4362-72. doi: 10.1016/j.vaccine.2011.04.010. Epub 2011 Apr 16.


A versatile papaya mosaic virus (PapMV) vaccine platform based on sortase-mediated antigen coupling.

Thérien A, Bédard M, Carignan D, Rioux G, Gauthier-Landry L, Laliberté-Gagné MÈ, Bolduc M, Savard P, Leclerc D.

J Nanobiotechnology. 2017 Jul 18;15(1):54. doi: 10.1186/s12951-017-0289-y.


Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms.

Ye X, Ku Z, Liu Q, Wang X, Shi J, Zhang Y, Kong L, Cong Y, Huang Z.

J Virol. 2014 Jan;88(1):72-81. doi: 10.1128/JVI.01848-13. Epub 2013 Oct 16.


A novel combined vaccine based on monochimeric VLP co-displaying multiple conserved epitopes against enterovirus 71 and varicella-zoster virus.

Wu Y, Zhu R, Xu L, Li Y, Li S, Yu H, Li S, Zhu H, Cheng T, Xia N.

Vaccine. 2017 May 9;35(20):2728-2735. doi: 10.1016/j.vaccine.2017.03.065. Epub 2017 Apr 10.


A universal T cell epitope-containing peptide from hepatitis B surface antigen can enhance antibody specific for HIV gp120.

Greenstein JL, Schad VC, Goodwin WH, Brauer AB, Bollinger BK, Chin RD, Kuo MC.

J Immunol. 1992 Jun 15;148(12):3970-7.


Engineering of papaya mosaic virus (PapMV) nanoparticles with a CTL epitope derived from influenza NP.

Babin C, Majeau N, Leclerc D.

J Nanobiotechnology. 2013 Apr 4;11:10. doi: 10.1186/1477-3155-11-10.


Structure-based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae.

Wang L, Xing D, Le Van A, Jerse AE, Wang S.

FEBS Open Bio. 2017 Jul 24;7(8):1196-1207. doi: 10.1002/2211-5463.12267. eCollection 2017 Aug.


Passive protection against lethal enterovirus 71 infection in newborn mice by neutralizing antibodies elicited by a synthetic peptide.

Foo DG, Alonso S, Chow VT, Poh CL.

Microbes Infect. 2007 Sep;9(11):1299-306. Epub 2007 Jun 10.


Peptide vaccines incorporating a 'promiscuous' T-cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity.

Kaumaya PT, Kobs-Conrad S, Seo YH, Lee H, VanBuskirk AM, Feng N, Sheridan JF, Stevens V.

J Mol Recognit. 1993 Jun;6(2):81-94.


Display of the Viral Epitopes on Lactococcus lactis: A Model for Food Grade Vaccine against EV71.

Varma NR, Toosa H, Foo HL, Alitheen NB, Nor Shamsudin M, Arbab AS, Yusoff K, Abdul Rahim R.

Biotechnol Res Int. 2013;2013:431315. doi: 10.1155/2013/431315. Epub 2013 Feb 13.


Hepatitis B virus core particles containing multiple epitopes confer protection against enterovirus 71 and coxsackievirus A16 infection in mice.

Huo C, Yang J, Lei L, Qiao L, Xin J, Pan Z.

Vaccine. 2017 Dec 19;35(52):7322-7330. doi: 10.1016/j.vaccine.2017.10.101. Epub 2017 Nov 10.


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