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Elevated expression of ICAM-1 in synovium is associated with early inflammatory response for cartilage degeneration in type 2 diabetes mellitus.

Gui T, Lin YK, Huan SW, Li YH, Wang BH, Yang J, Gu RH, Liu Q, Li ZY, Li SM, Chen YF, Zhang HT, Zha ZG.

J Cell Biochem. 2019 Mar 19. doi: 10.1002/jcb.28592. [Epub ahead of print]


The role of cytokines in osteoarthritis pathophysiology.

Fernandes JC, Martel-Pelletier J, Pelletier JP.

Biorheology. 2002;39(1-2):237-46. Review.


Darapladib inhibits atherosclerosis development in type 2 diabetes mellitus Sprague-Dawley rat model.

Wihastuti TA, Heriansyah T, Hanifa H, Andarini S, Sholichah Z, Sulfia YH, Adam AA, Refialdinata J, Lutfiana NC.

Endocr Regul. 2018 Apr 1;52(2):69-75. doi: 10.2478/enr-2018-0008.


Effect of advanced oxidation protein products on articular cartilage and synovium in a rabbit osteoarthritis model.

Yu H, Ye WB, Zhong ZM, Ding RT, Chen JT.

Orthop Surg. 2015 May;7(2):161-7. doi: 10.1111/os.12179.


Carnosine Prevents Type 2 Diabetes-Induced Osteoarthritis Through the ROS/NF-κB Pathway.

Yang Y, Wang Y, Kong Y, Zhang X, Zhang H, Gang Y, Bai L.

Front Pharmacol. 2018 Jun 6;9:598. doi: 10.3389/fphar.2018.00598. eCollection 2018.


Joint distraction attenuates osteoarthritis by reducing secondary inflammation, cartilage degeneration and subchondral bone aberrant change.

Chen Y, Sun Y, Pan X, Ho K, Li G.

Osteoarthritis Cartilage. 2015 Oct;23(10):1728-35. doi: 10.1016/j.joca.2015.05.018. Epub 2015 May 29.


Characterisation of osteoarthritis in a small animal model of type 2 diabetes mellitus.

Onur T, Wu R, Metz L, Dang A.

Bone Joint Res. 2014 Jun;3(6):203-11. doi: 10.1302/2046-3758.36.2000244.


Diabetes-accelerated experimental osteoarthritis is prevented by autophagy activation.

Ribeiro M, López de Figueroa P, Nogueira-Recalde U, Centeno A, Mendes AF, Blanco FJ, Caramés B.

Osteoarthritis Cartilage. 2016 Dec;24(12):2116-2125. doi: 10.1016/j.joca.2016.06.019. Epub 2016 Jul 5.


The nuclear factor-erythroid 2-related factor/heme oxygenase-1 axis is critical for the inflammatory features of type 2 diabetes-associated osteoarthritis.

Vaamonde-Garcia C, Courties A, Pigenet A, Laiguillon MC, Sautet A, Houard X, Kerdine-Römer S, Meijide R, Berenbaum F, Sellam J.

J Biol Chem. 2017 Sep 1;292(35):14505-14515. doi: 10.1074/jbc.M117.802157. Epub 2017 Jul 6.


Metabolic dysregulation accelerates injury-induced joint degeneration, driven by local inflammation; an in vivo rat study.

de Visser HM, Mastbergen SC, Kozijn AE, Coeleveld K, Pouran B, van Rijen MH, Lafeber FPJG, Weinans H.

J Orthop Res. 2018 Mar;36(3):881-890. doi: 10.1002/jor.23712. Epub 2017 Sep 20.


Treatment with recombinant lubricin attenuates osteoarthritis by positive feedback loop between articular cartilage and subchondral bone in ovariectomized rats.

Cui Z, Xu C, Li X, Song J, Yu B.

Bone. 2015 May;74:37-47. doi: 10.1016/j.bone.2014.12.065. Epub 2015 Jan 7.


Control of Dkk-1 ameliorates chondrocyte apoptosis, cartilage destruction, and subchondral bone deterioration in osteoarthritic knees.

Weng LH, Wang CJ, Ko JY, Sun YC, Wang FS.

Arthritis Rheum. 2010 May;62(5):1393-402. doi: 10.1002/art.27357.


Dkk-1 promotes angiogenic responses and cartilage matrix proteinase secretion in synovial fibroblasts from osteoarthritic joints.

Weng LH, Ko JY, Wang CJ, Sun YC, Wang FS.

Arthritis Rheum. 2012 Oct;64(10):3267-77. doi: 10.1002/art.34602.


Expression of MMP-1 in cartilage and synovium of experimentally induced rabbit ACLT traumatic osteoarthritis: immunohistochemical study.

Wu H, Du J, Zheng Q.

Rheumatol Int. 2008 Nov;29(1):31-6. doi: 10.1007/s00296-008-0636-2. Epub 2008 Jul 3.


Cartilage degradation in osteoarthritis: A process of osteochondral remodeling resembles the endochondral ossification in growth plate?

Xiao ZF, Su GY, Hou Y, Chen SD, Lin DK.

Med Hypotheses. 2018 Dec;121:183-187. doi: 10.1016/j.mehy.2018.08.023. Epub 2018 Aug 27.


Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.

Joosten LA, Lubberts E, Helsen MM, Saxne T, Coenen-de Roo CJ, Heinegård D, van den Berg WB.

Arthritis Res. 1999;1(1):81-91. Epub 1999 Oct 26.


Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.

Davidson RK, Waters JG, Kevorkian L, Darrah C, Cooper A, Donell ST, Clark IM.

Arthritis Res Ther. 2006;8(4):R124.


Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis.

Kyostio-Moore S, Piraino S, Berthelette P, Moran N, Serriello J, Bendele A, Sookdeo C, Nambiar B, Ewing P, Armentano D, Matthews GL.

Arthritis Res Ther. 2015 Jan 16;17:5. doi: 10.1186/s13075-015-0519-3.

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