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Items: 1 to 20 of 105

1.

NGS-based profiling reveals a critical contributing role of somatic D-loop mtDNA mutations in HBV-related hepatocarcinogenesis.

Yin C, Li DY, Guo X, Cao HY, Chen YB, Zhou F, Ge NJ, Liu Y, Guo SS, Zhao Z, Yang HS, Xing JL.

Ann Oncol. 2019 Mar 18. pii: mdz105. doi: 10.1093/annonc/mdz105. [Epub ahead of print]

PMID:
30887045
2.

Multi-regional sequencing reveals intratumor heterogeneity and positive selection of somatic mtDNA mutations in hepatocellular carcinoma and colorectal cancer.

Li X, Guo X, Li D, Du X, Yin C, Chen C, Fang W, Bian Z, Zhang J, Li B, Yang H, Xing J.

Int J Cancer. 2018 Sep 1;143(5):1143-1152. doi: 10.1002/ijc.31395. Epub 2018 Apr 16.

PMID:
29569724
3.

Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma.

Lee HC, Li SH, Lin JC, Wu CC, Yeh DC, Wei YH.

Mutat Res. 2004 Mar 22;547(1-2):71-8.

PMID:
15013701
4.

Applications of next-generation sequencing analysis for the detection of hepatocellular carcinoma-associated hepatitis B virus mutations.

Wu IC, Liu WC, Chang TT.

J Biomed Sci. 2018 Jun 2;25(1):51. doi: 10.1186/s12929-018-0442-4. Review.

5.

Correlation between clinical characteristics and mitochondrial D-loop DNA mutations in hepatocellular carcinoma.

Tamori A, Nishiguchi S, Nishikawa M, Kubo S, Koh N, Hirohashi K, Shiomi S, Inoue M.

J Gastroenterol. 2004 Nov;39(11):1063-8.

PMID:
15580399
6.

Mutations in the D-loop region and increased copy number of mitochondrial DNA in human laryngeal squamous cell carcinoma.

Guo W, Yang D, Xu H, Zhang Y, Huang J, Yang Z, Chen X, Huang Z.

Mol Biol Rep. 2013 Jan;40(1):13-20. doi: 10.1007/s11033-012-1939-7. Epub 2012 Nov 1.

PMID:
23114912
7.

Whole genome sequencing of matched tumor, adjacent non-tumor tissues and corresponding normal blood samples of hepatocellular carcinoma patients revealed dynamic changes of the mutations profiles during hepatocarcinogenesis.

Mao R, Liu J, Liu G, Jin S, Xue Q, Ma L, Fu Y, Zhao N, Xing J, Li L, Qiu Y, Lin B.

Oncotarget. 2017 Apr 18;8(16):26185-26199. doi: 10.18632/oncotarget.15428.

8.

[Mutations in the D-loop region of mitochondrial DNA and the ROS level in the tissue of hepatocellular carcinoma].

Huang XW, Zhao Q, Chen DZ, Zhang LS.

Yi Chuan. 2005 Jan;27(1):14-20. Chinese.

PMID:
15730952
9.

Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid.

Zhu W, Qin W, Bradley P, Wessel A, Puckett CL, Sauter ER.

Carcinogenesis. 2005 Jan;26(1):145-52. Epub 2004 Sep 16.

PMID:
15375011
10.

Detection of mitochondrial DNA alterations in the serum of hepatocellular carcinoma patients.

Okochi O, Hibi K, Uemura T, Inoue S, Takeda S, Kaneko T, Nakao A.

Clin Cancer Res. 2002 Sep;8(9):2875-8.

11.

Molecular mechanism of hepatocarcinogenesis.

Sheu JC.

J Gastroenterol Hepatol. 1997 Oct;12(9-10):S309-13. Review.

PMID:
9407351
12.

Integration of tumour and viral genomic characterizations in HBV-related hepatocellular carcinomas.

Amaddeo G, Cao Q, Ladeiro Y, Imbeaud S, Nault JC, Jaoui D, Gaston Mathe Y, Laurent C, Laurent A, Bioulac-Sage P, Calderaro J, Zucman-Rossi J.

Gut. 2015 May;64(5):820-9. doi: 10.1136/gutjnl-2013-306228. Epub 2014 Jun 9.

13.

Identification of sequence polymorphism in the D-Loop region of mitochondrial DNA as a risk factor for hepatocellular carcinoma with distinct etiology.

Zhang R, Zhang F, Wang C, Wang S, Shiao YH, Guo Z.

J Exp Clin Cancer Res. 2010 Sep 18;29:130. doi: 10.1186/1756-9966-29-130.

14.

Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer.

Hung WY, Wu CW, Yin PH, Chang CJ, Li AF, Chi CW, Wei YH, Lee HC.

Biochim Biophys Acta. 2010 Mar;1800(3):264-70. doi: 10.1016/j.bbagen.2009.06.006. Epub 2009 Jun 13.

PMID:
19527772
15.

Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma.

Yin PH, Lee HC, Chau GY, Wu YT, Li SH, Lui WY, Wei YH, Liu TY, Chi CW.

Br J Cancer. 2004 Jun 14;90(12):2390-6.

16.

Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer.

Tseng LM, Yin PH, Chi CW, Hsu CY, Wu CW, Lee LM, Wei YH, Lee HC.

Genes Chromosomes Cancer. 2006 Jul;45(7):629-38.

PMID:
16568452
17.

Validation of Next-Generation Sequencing of Entire Mitochondrial Genomes and the Diversity of Mitochondrial DNA Mutations in Oral Squamous Cell Carcinoma.

Kloss-Brandstätter A, Weissensteiner H, Erhart G, Schäfer G, Forer L, Schönherr S, Pacher D, Seifarth C, Stöckl A, Fendt L, Sottsas I, Klocker H, Huck CW, Rasse M, Kronenberg F, Kloss FR.

PLoS One. 2015 Aug 11;10(8):e0135643. doi: 10.1371/journal.pone.0135643. eCollection 2015.

18.

Associations between sequence variations in the mitochondrial DNA D-loop region and outcome of hepatocellular carcinoma.

Li S, Wan P, Peng T, Xiao K, Su M, Shang L, Xu B, Su Z, Ye X, Peng N, Qin Q, Li L.

Oncol Lett. 2016 Jun;11(6):3723-3728. Epub 2016 Apr 19.

19.

Number of somatic mutations in the mitochondrial D-loop region indicates poor prognosis in breast cancer, independent of TP53 mutation.

Kuo SJ, Chen M, Ma GC, Chen ST, Chang SP, Lin WY, Chen YC, Lee TH, Lin TT, Liu CS.

Cancer Genet Cytogenet. 2010 Sep;201(2):94-101. doi: 10.1016/j.cancergencyto.2010.05.013.

PMID:
20682393
20.

Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma.

Nomoto S, Yamashita K, Koshikawa K, Nakao A, Sidransky D.

Clin Cancer Res. 2002 Feb;8(2):481-7.

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