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Items: 1 to 20 of 100

1.

Di(2-ethylhexyl) phthalate promotes hepatic fibrosis by regulation of oxidative stress and inflammation responses in rats.

Zhao ZB, Ji K, Shen XY, Zhang WW, Wang R, Xu WP, Wei W.

Environ Toxicol Pharmacol. 2019 May;68:109-119. doi: 10.1016/j.etap.2019.03.008. Epub 2019 Mar 8.

PMID:
30884453
2.

Liuweiwuling tablets attenuate BDL-induced hepatic fibrosis via modulation of TGF-β/Smad and NF-κB signaling pathways.

Liu H, Dong F, Li G, Niu M, Zhang C, Han Y, He L, Yin P, Wang B, Sang X, Li R, Wang J, Bai Z, Xiao X.

J Ethnopharmacol. 2018 Jan 10;210:232-241. doi: 10.1016/j.jep.2017.08.029. Epub 2017 Aug 31.

PMID:
28864168
3.

Isorhamnetin attenuates liver fibrosis by inhibiting TGF-β/Smad signaling and relieving oxidative stress.

Yang JH, Kim SC, Kim KM, Jang CH, Cho SS, Kim SJ, Ku SK, Cho IJ, Ki SH.

Eur J Pharmacol. 2016 Jul 15;783:92-102. doi: 10.1016/j.ejphar.2016.04.042. Epub 2016 May 3.

PMID:
27151496
4.

Cav-1 deficiency promotes liver fibrosis in carbon tetrachloride (CCl4)-induced mice by regulation of oxidative stress and inflammation responses.

Ji DG, Zhang Y, Yao SM, Zhai XJ, Zhang LR, Zhang YZ, Li H.

Biomed Pharmacother. 2018 Jun;102:26-33. doi: 10.1016/j.biopha.2018.03.016. Epub 2018 Mar 14.

PMID:
29549726
5.

Plasticizer Di-(2-Ethylhexyl)Phthalate Induces Epithelial-to-Mesenchymal Transition and Renal Fibrosis In Vitro and In Vivo.

Wu CT, Wang CC, Huang LC, Liu SH, Chiang CK.

Toxicol Sci. 2018 Jul 1;164(1):363-374. doi: 10.1093/toxsci/kfy094.

PMID:
29669060
6.

Umbelliferone Ameliorates CCl4-Induced Liver Fibrosis in Rats by Upregulating PPARγ and Attenuating Oxidative Stress, Inflammation, and TGF-β1/Smad3 Signaling.

Mahmoud AM, Hozayen WG, Hasan IH, Shaban E, Bin-Jumah M.

Inflammation. 2019 Feb 11. doi: 10.1007/s10753-019-00973-8. [Epub ahead of print]

PMID:
30741365
7.

Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway.

Mu M, Zuo S, Wu RM, Deng KS, Lu S, Zhu JJ, Zou GL, Yang J, Cheng ML, Zhao XK.

Drug Des Devel Ther. 2018 Dec 3;12:4107-4115. doi: 10.2147/DDDT.S186726. eCollection 2018.

8.

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway.

Yu DK, Zhang CX, Zhao SS, Zhang SH, Zhang H, Cai SY, Shao RG, He HW.

Acta Pharmacol Sin. 2015 Apr;36(4):473-82. doi: 10.1038/aps.2014.155. Epub 2015 Mar 16.

9.
10.

Dimethylfumarate ameliorates hepatic injury and fibrosis induced by carbon tetrachloride.

Mostafa ME, Shaaban AA, Salem HA.

Chem Biol Interact. 2019 Apr 1;302:53-60. doi: 10.1016/j.cbi.2019.01.029. Epub 2019 Jan 28.

PMID:
30703375
11.

[Dynamic expression of TGF-beta1/Smad protein in CCl4-induced liver fibrosis and its significance in rats].

Bao JF, Shi JP, Xu S.

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Oct;25(5):334-7. Chinese.

PMID:
22338217
12.

Evodiamine ameliorates liver fibrosis in rats via TGF-β1/Smad signaling pathway.

Yang D, Li L, Qian S, Liu L.

J Nat Med. 2018 Jan;72(1):145-154. doi: 10.1007/s11418-017-1122-5. Epub 2017 Sep 21.

PMID:
28936800
13.

Sauchinone attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway.

Lee JH, Jang EJ, Seo HL, Ku SK, Lee JR, Shin SS, Park SD, Kim SC, Kim YW.

Chem Biol Interact. 2014 Dec 5;224:58-67. doi: 10.1016/j.cbi.2014.10.005. Epub 2014 Oct 16.

PMID:
25451574
14.

Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation.

Zhou Y, Tong X, Ren S, Wang X, Chen J, Mu Y, Sun M, Chen G, Zhang H, Liu P.

J Ethnopharmacol. 2016 Aug 22;190:83-90. doi: 10.1016/j.jep.2016.06.011. Epub 2016 Jun 6.

PMID:
27282665
15.

Di(2-ethylhexyl) phthalate induced hepatotoxicity in quail (Coturnix japonica) via modulating the mitochondrial unfolded protein response and NRF2 mediated antioxidant defense.

Zhang Q, Zhao Y, Talukder M, Han Y, Zhang C, Li XN, Li JL.

Sci Total Environ. 2019 Feb 15;651(Pt 1):885-894. doi: 10.1016/j.scitotenv.2018.09.211. Epub 2018 Sep 17.

PMID:
30257229
16.
17.

Smad2 increases the apoptosis of activated human hepatic stellate cells induced by TRAIL.

Xu F, Zhou D, Meng X, Wang X, Liu C, Huang C, Li J, Zhang L.

Int Immunopharmacol. 2016 Mar;32:76-86. doi: 10.1016/j.intimp.2016.01.013. Epub 2016 Jan 21.

PMID:
26802603
18.

Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways.

Hernández-Aquino E, Zarco N, Casas-Grajales S, Ramos-Tovar E, Flores-Beltrán RE, Arauz J, Shibayama M, Favari L, Tsutsumi V, Segovia J, Muriel P.

World J Gastroenterol. 2017 Jun 28;23(24):4354-4368. doi: 10.3748/wjg.v23.i24.4354.

19.

Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.

Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X.

Int J Mol Sci. 2015 Sep 10;16(9):21911-30. doi: 10.3390/ijms160921911.

20.

Smad2 protects against TGF-β1/Smad3-mediated collagen synthesis in human hepatic stellate cells during hepatic fibrosis.

Zhang L, Liu C, Meng XM, Huang C, Xu F, Li J.

Mol Cell Biochem. 2015 Feb;400(1-2):17-28. doi: 10.1007/s11010-014-2258-1. Epub 2014 Oct 29.

PMID:
25351340

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