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Items: 1 to 20 of 103

1.

Autophagy induction by xanthoangelol exhibits anti-metastatic activities in hepatocellular carcinoma.

Yang X, Xie J, Liu X, Li Z, Fang K, Zhang L, Han M, Zhang Z, Gong Z, Lin X, Shi X, Gao H, Lu K.

Cell Biochem Funct. 2019 Apr;37(3):128-138. doi: 10.1002/cbf.3374. Epub 2019 Mar 18.

PMID:
30883849
2.

Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma.

Li Z, Zhang L, Gao M, Han M, Liu K, Zhang Z, Gong Z, Xing L, Shi X, Lu K, Gao H.

J Exp Clin Cancer Res. 2019 Jan 8;38(1):8. doi: 10.1186/s13046-018-1012-z.

3.

Two chalcones, 4-hydroxyderricin and xanthoangelol, stimulate GLUT4-dependent glucose uptake through the LKB1/AMP-activated protein kinase signaling pathway in 3T3-L1 adipocytes.

Ohta M, Fujinami A, Kobayashi N, Amano A, Ishigami A, Tokuda H, Suzuki N, Ito F, Mori T, Sawada M, Iwasa K, Kitawaki J, Ohnishi K, Tsujikawa M, Obayashi H.

Nutr Res. 2015 Jul;35(7):618-25. doi: 10.1016/j.nutres.2015.05.010. Epub 2015 May 30.

PMID:
26077869
4.

Hispidulin induces ER stress-mediated apoptosis in human hepatocellular carcinoma cells in vitro and in vivo by activating AMPK signaling pathway.

Han M, Gao H, Xie J, Yuan YP, Yuan Q, Gao MQ, Liu KL, Chen XH, Han YT, Han ZW.

Acta Pharmacol Sin. 2018 Sep 14. doi: 10.1038/s41401-018-0159-7. [Epub ahead of print]

PMID:
30218072
5.

Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPAR╬│.

Han M, Gao H, Ju P, Gao MQ, Yuan YP, Chen XH, Liu KL, Han YT, Han ZW.

Biomed Pharmacother. 2018 Jul;103:272-283. doi: 10.1016/j.biopha.2018.04.014. Epub 2018 Apr 24.

PMID:
29656183
6.

Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.

Jiang J, Chen S, Li K, Zhang C, Tan Y, Deng Q, Chai Y, Wang X, Chen G, Feng K, Zhang L, Xie CM, Ma K.

Int J Hyperthermia. 2019 Apr 22:1-12. doi: 10.1080/02656736.2019.1600052. [Epub ahead of print]

PMID:
31007109
7.

Protective autophagy induced by physcion suppresses hepatocellular carcinoma cell metastasis by inactivating the JAK2/STAT3 Axis.

Pan X, Wang C, Li Y, Zhu L, Zhang T.

Life Sci. 2018 Dec 1;214:124-135. doi: 10.1016/j.lfs.2018.10.064. Epub 2018 Oct 30.

PMID:
30389439
8.

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.

Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC.

Carcinogenesis. 2013 Jun;34(6):1331-42. doi: 10.1093/carcin/bgt060. Epub 2013 Feb 7.

PMID:
23393227
9.

Comprehensive anti-tumor effect of Brusatol through inhibition of cell viability and promotion of apoptosis caused by autophagy via the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.

Ye R, Dai N, He Q, Guo P, Xiang Y, Zhang Q, Hong Z, Zhang Q.

Biomed Pharmacother. 2018 Sep;105:962-973. doi: 10.1016/j.biopha.2018.06.065. Epub 2018 Jun 19.

PMID:
30021391
10.

Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation.

Gao L, Lv G, Li R, Liu WT, Zong C, Ye F, Li XY, Yang X, Jiang JH, Hou XJ, Jing YY, Han ZP, Wei LX.

Cancer Lett. 2019 Apr 10. pii: S0304-3835(19)30234-4. doi: 10.1016/j.canlet.2019.04.009. [Epub ahead of print]

11.

Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells.

Peng YF, Shi YH, Ding ZB, Ke AW, Gu CY, Hui B, Zhou J, Qiu SJ, Dai Z, Fan J.

Autophagy. 2013 Dec;9(12):2056-68. doi: 10.4161/auto.26398. Epub 2013 Oct 1.

PMID:
24157892
12.

4-Hydroxyderricin and xanthoangelol from Ashitaba (Angelica keiskei) suppress differentiation of preadiopocytes to adipocytes via AMPK and MAPK pathways.

Zhang T, Sawada K, Yamamoto N, Ashida H.

Mol Nutr Food Res. 2013 Oct;57(10):1729-40. doi: 10.1002/mnfr.201300020. Epub 2013 May 16.

PMID:
23681764
13.

Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.

Kwon HY, Kim JH, Kim B, Srivastava SK, Kim SH.

Arch Toxicol. 2018 Jan;92(1):241-257. doi: 10.1007/s00204-017-2021-y. Epub 2017 Jul 4. Erratum in: Arch Toxicol. 2018 Sep;92(9):2979.

PMID:
28676953
14.

Autophagy induction by silibinin positively contributes to its anti-metastatic capacity via AMPK/mTOR pathway in renal cell carcinoma.

Li F, Ma Z, Guan Z, Chen Y, Wu K, Guo P, Wang X, He D, Zeng J.

Int J Mol Sci. 2015 Apr 15;16(4):8415-29. doi: 10.3390/ijms16048415.

15.

A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating ╬▒-Tubulin Expression.

Chang WT, Liu W, Chiu YH, Chen BH, Chuang SC, Chen YC, Hsu YT, Lu MJ, Chiou SJ, Chou CK, Chiu CC.

Molecules. 2017 May 21;22(5). pii: E854. doi: 10.3390/molecules22050854.

16.

Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling.

Han B, Yu YQ, Yang QL, Shen CY, Wang XJ.

Oncotarget. 2017 Sep 16;8(49):86227-86239. doi: 10.18632/oncotarget.21043. eCollection 2017 Oct 17.

17.

Thymoquinone inhibits the metastasis of renal cell cancer cells by inducing autophagy via AMPK/mTOR signaling pathway.

Zhang Y, Fan Y, Huang S, Wang G, Han R, Lei F, Luo A, Jing X, Zhao L, Gu S, Zhao X.

Cancer Sci. 2018 Dec;109(12):3865-3873. doi: 10.1111/cas.13808. Epub 2018 Oct 28.

18.

Tissue kallikrein protects SH-SY5Y neuronal cells against oxygen and glucose deprivation-induced injury through bradykinin B2 receptor-dependent regulation of autophagy induction.

Liu Y, Lu Z, Cui M, Yang Q, Tang Y, Dong Q.

J Neurochem. 2016 Oct;139(2):208-220. doi: 10.1111/jnc.13690. Epub 2016 Sep 15.

19.

Tris (1, 3-dichloro-2-propyl) phosphate induces apoptosis and autophagy in SH-SY5Y cells: Involvement of ROS-mediated AMPK/mTOR/ULK1 pathways.

Li R, Zhou P, Guo Y, Lee JS, Zhou B.

Food Chem Toxicol. 2017 Feb;100:183-196. doi: 10.1016/j.fct.2016.12.029. Epub 2016 Dec 23.

PMID:
28025121
20.

Globular Adiponectin Attenuated H2O2-Induced Apoptosis in Rat Chondrocytes by Inducing Autophagy Through the AMPK/ mTOR Pathway.

Hu J, Cui W, Ding W, Gu Y, Wang Z, Fan W.

Cell Physiol Biochem. 2017;43(1):367-382. doi: 10.1159/000480416. Epub 2017 Aug 31.

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