Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 117

1.

Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.

Zhou L, Liu L, Chai W, Zhao T, Jin X, Guo X, Han L, Yuan C.

Onco Targets Ther. 2019 Feb 28;12:1729-1739. doi: 10.2147/OTT.S194329. eCollection 2019.

2.

The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases.

Rueda EM, Johnson JE Jr, Giddabasappa A, Swaroop A, Brooks MJ, Sigel I, Chaney SY, Fox DA.

Mol Vis. 2016 Jul 23;22:847-85. eCollection 2016.

3.

The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanism.

Lu J, Tan M, Cai Q.

Cancer Lett. 2015 Jan 28;356(2 Pt A):156-64. doi: 10.1016/j.canlet.2014.04.001. Epub 2014 Apr 13. Review.

4.

Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect.

Lu CL, Qin L, Liu HC, Candas D, Fan M, Li JJ.

PLoS One. 2015 Mar 25;10(3):e0121046. doi: 10.1371/journal.pone.0121046. eCollection 2015.

5.

PDK1 inhibition is a novel therapeutic target in multiple myeloma.

Fujiwara S, Kawano Y, Yuki H, Okuno Y, Nosaka K, Mitsuya H, Hata H.

Br J Cancer. 2013 Jan 15;108(1):170-8. doi: 10.1038/bjc.2012.527. Epub 2012 Nov 29.

6.

Nutrient deprivation-related OXPHOS/glycolysis interconversion via HIF-1α/C-MYC pathway in U251 cells.

Liu Z, Sun Y, Tan S, Liu L, Hu S, Huo H, Li M, Cui Q, Yu M.

Tumour Biol. 2016 May;37(5):6661-71. doi: 10.1007/s13277-015-4479-7. Epub 2015 Dec 8.

PMID:
26646563
7.

Dual-targeting of aberrant glucose metabolism in glioblastoma.

Shen H, Decollogne S, Dilda PJ, Hau E, Chung SA, Luk PP, Hogg PJ, McDonald KL.

J Exp Clin Cancer Res. 2015 Feb 5;34:14. doi: 10.1186/s13046-015-0130-0.

8.

The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition.

Brandi J, Cecconi D, Cordani M, Torrens-Mas M, Pacchiana R, Dalla Pozza E, Butera G, Manfredi M, Marengo E, Oliver J, Roca P, Dando I, Donadelli M.

Free Radic Biol Med. 2016 Dec;101:305-316. doi: 10.1016/j.freeradbiomed.2016.10.499. Epub 2016 Oct 27.

PMID:
27989750
9.

α-Lactalbumin-oleic acid complex kills tumor cells by inducing excess energy metabolism but inhibiting mRNA expression of the related enzymes.

Fang B, Zhang M, Ge KS, Xing HZ, Ren FZ.

J Dairy Sci. 2018 Jun;101(6):4853-4863. doi: 10.3168/jds.2017-13731. Epub 2018 Mar 15.

10.

Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress.

Goto M, Miwa H, Suganuma K, Tsunekawa-Imai N, Shikami M, Mizutani M, Mizuno S, Hanamura I, Nitta M.

BMC Cancer. 2014 Feb 10;14:76. doi: 10.1186/1471-2407-14-76.

11.

Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.

Chen Y, Cairns R, Papandreou I, Koong A, Denko NC.

PLoS One. 2009 Sep 15;4(9):e7033. doi: 10.1371/journal.pone.0007033.

12.

Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer.

Roh JL, Park JY, Kim EH, Jang HJ, Kwon M.

Cancer Lett. 2016 Feb 1;371(1):20-9. doi: 10.1016/j.canlet.2015.11.023. Epub 2015 Nov 23.

PMID:
26607904
13.

Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.

Stockwin LH, Yu SX, Borgel S, Hancock C, Wolfe TL, Phillips LR, Hollingshead MG, Newton DL.

Int J Cancer. 2010 Dec 1;127(11):2510-9. doi: 10.1002/ijc.25499.

14.

Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.

Neveu MA, De Preter G, Joudiou N, Bol A, Brender JR, Saito K, Kishimoto S, Grégoire V, Jordan BF, Krishna MC, Feron O, Gallez B.

Oncotarget. 2016 Dec 6;7(49):81741-81749. doi: 10.18632/oncotarget.13176.

15.

Nutrient deprivation induces the Warburg effect through ROS/AMPK-dependent activation of pyruvate dehydrogenase kinase.

Wu CA, Chao Y, Shiah SG, Lin WW.

Biochim Biophys Acta. 2013 May;1833(5):1147-56. doi: 10.1016/j.bbamcr.2013.01.025. Epub 2013 Jan 31.

16.

ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells.

Xu Y, Gao W, Zhang Y, Wu S, Liu Y, Deng X, Xie L, Yang J, Yu H, Su J, Sun L.

Int J Oncol. 2018 Sep;53(3):1055-1068. doi: 10.3892/ijo.2018.4476. Epub 2018 Jul 9.

17.

Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling.

Zhdanov AV, Waters AH, Golubeva AV, Dmitriev RI, Papkovsky DB.

Biochim Biophys Acta. 2014 Jan;1837(1):51-62. doi: 10.1016/j.bbabio.2013.07.008. Epub 2013 Jul 23.

18.
19.

Metabolic targeting as an anticancer strategy: dawn of a new era?

Pan JG, Mak TW.

Sci STKE. 2007 Apr 10;2007(381):pe14.

PMID:
17426345
20.

2-Deoxy-D-glucose enhances dichloroacetate antitumor action against Lewis lung carcinoma.

Pyaskovskaya ON, Kolesnik DL, Fedorchuk AG, Prokhorova IV, Solyanik GI.

Exp Oncol. 2016 Sep;38(3):176-80.

PMID:
27685525

Supplemental Content

Support Center