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Items: 1 to 20 of 108

1.

STING-mediated intestinal barrier dysfunction contributes to lethal sepsis.

Hu Q, Ren H, Li G, Wang D, Zhou Q, Wu J, Zheng J, Huang J, Slade DA, Wu X, Ren J.

EBioMedicine. 2019 Mar;41:497-508. doi: 10.1016/j.ebiom.2019.02.055. Epub 2019 Mar 14.

2.

STING and TRIF Contribute to Mouse Sepsis, Depending on Severity of the Disease Model.

Heipertz EL, Harper J, Walker WE.

Shock. 2017 May;47(5):621-631. doi: 10.1097/SHK.0000000000000771.

PMID:
27755506
3.

The emerging role of stimulator of interferons genes signaling in sepsis: Inflammation, autophagy, and cell death.

Hu Q, Knight PH, Ren Y, Ren H, Zheng J, Wu X, Ren J, Sawyer RG.

Acta Physiol (Oxf). 2019 Mar;225(3):e13194. doi: 10.1111/apha.13194. Epub 2018 Oct 22. Review.

PMID:
30269441
4.

LDK378 improves micro- and macro-circulation via alleviating STING-mediated inflammatory injury in a Sepsis rat model induced by Cecal ligation and puncture.

Ge W, Hu Q, Fang X, Liu J, Xu J, Hu J, Liu X, Ling Q, Wang Y, Li H, Gao M, Jiang L, Yang Z, Tang W.

J Inflamm (Lond). 2019 Feb 18;16:3. doi: 10.1186/s12950-019-0208-0. eCollection 2019.

5.

Naringin attenuates MLC phosphorylation and NF-κB activation to protect sepsis-induced intestinal injury via RhoA/ROCK pathway.

Li Z, Gao M, Yang B, Zhang H, Wang K, Liu Z, Xiao X, Yang M.

Biomed Pharmacother. 2018 Jul;103:50-58. doi: 10.1016/j.biopha.2018.03.163. Epub 2018 Apr 7.

PMID:
29635128
6.

Orexigenic hormone ghrelin ameliorates gut barrier dysfunction in sepsis in rats.

Wu R, Dong W, Qiang X, Wang H, Blau SA, Ravikumar TS, Wang P.

Crit Care Med. 2009 Aug;37(8):2421-6. doi: 10.1097/CCM.0b013e3181a557a2.

7.

Changes of the immunological barrier of intestinal mucosa in rats with sepsis.

Jiang LY, Zhang M, Zhou TE, Yang ZF, Wen LQ, Chang JX.

World J Emerg Med. 2010;1(2):138-43.

8.

Repair of damaged intestinal mucosa in a mouse model of sepsis.

Chang RM, Wen LQ, Chang JX, Fu YR, Jiang ZP, Chen S.

World J Emerg Med. 2013;4(3):223-8. doi: 10.5847/wjem.j.1920-8642.2013.03.012.

9.

Role of pulmonary microvascular endothelial cell apoptosis in murine sepsis-induced lung injury in vivo.

Gill SE, Rohan M, Mehta S.

Respir Res. 2015 Sep 16;16:109. doi: 10.1186/s12931-015-0266-7.

10.

EFFECT OF GTS-21, AN ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONIST, ON CLP-INDUCED INFLAMMATORY, GASTROINTESTINAL MOTILITY, AND COLONIC PERMEABILITY CHANGES IN MICE.

Nullens S, Staessens M, Peleman C, Schrijvers DM, Malhotra-Kumar S, Francque S, Matteoli G, Boeckxstaens GE, De Man JG, De Winter BY.

Shock. 2016 Apr;45(4):450-9. doi: 10.1097/SHK.0000000000000519.

PMID:
26618987
11.

Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.

Fredenburgh LE, Velandia MM, Ma J, Olszak T, Cernadas M, Englert JA, Chung SW, Liu X, Begay C, Padera RF, Blumberg RS, Walsh SR, Baron RM, Perrella MA.

J Immunol. 2011 Nov 15;187(10):5255-67. doi: 10.4049/jimmunol.1101186. Epub 2011 Oct 3.

12.

Targeting palmitoyl acyltransferase ZDHHC21 improves gut epithelial barrier dysfunction resulting from burn-induced systemic inflammation.

Haines RJ, Wang CY, Yang CGY, Eitnier RA, Wang F, Wu MH.

Am J Physiol Gastrointest Liver Physiol. 2017 Dec 1;313(6):G549-G557. doi: 10.1152/ajpgi.00145.2017. Epub 2017 Aug 24.

13.

Omi/HtrA2 Regulates a Mitochondria-Dependent Apoptotic Pathway in a Murine Model of Septic Encephalopathy.

Wang P, Hu Y, Yao D, Li Y.

Cell Physiol Biochem. 2018;49(6):2163-2173. doi: 10.1159/000493819. Epub 2018 Oct 4.

14.

Protective effect of pioglitazone on sepsis-induced intestinal injury in a rodent model.

Gao M, Jiang Y, Xiao X, Peng Y, Xiao X, Yang M.

J Surg Res. 2015 May 15;195(2):550-8. doi: 10.1016/j.jss.2015.02.007. Epub 2015 Feb 13.

PMID:
25772146
15.

Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption.

Wu X, Ren J, Chen G, Wu L, Song X, Li G, Deng Y, Wang G, Gu G, Li J.

Sci Rep. 2017 Jun 29;7(1):4364. doi: 10.1038/s41598-017-04231-5.

16.

G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.

Chen G, Huang B, Fu S, Li B, Ran X, He D, Jiang L, Li Y, Liu B, Xie L, Liu J, Wang W.

Front Immunol. 2018 Sep 13;9:2079. doi: 10.3389/fimmu.2018.02079. eCollection 2018.

17.

Berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway.

Li GX, Wang XM, Jiang T, Gong JF, Niu LY, Li N.

Eur J Pharmacol. 2014 May 5;730:1-7. doi: 10.1016/j.ejphar.2014.02.006. Epub 2014 Feb 14.

PMID:
24530556
18.

Effect of early fluid resuscitation combined with low dose cyclophosphamide on intestinal barrier function in severe sepsis rats.

Tang SY, Zhang SW, Zhang J, Dong JT, Wu JD, Guo P, Yang JT, Zhang WJ, Wu F.

Drug Deliv Transl Res. 2018 Oct;8(5):1254-1264. doi: 10.1007/s13346-018-0573-x.

PMID:
30112606
19.
20.

Anti-apoptotic PI3K/Akt signaling by sodium/glucose transporter 1 reduces epithelial barrier damage and bacterial translocation in intestinal ischemia.

Huang CY, Hsiao JK, Lu YZ, Lee TC, Yu LC.

Lab Invest. 2011 Feb;91(2):294-309. doi: 10.1038/labinvest.2010.177. Epub 2010 Oct 25.

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