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LDB1 Is Required for the Early Development of the Dorsal Telencephalon and the Thalamus.

Kinare V, Pal S, Tole S.

eNeuro. 2019 Mar 12;6(1). pii: ENEURO.0356-18.2019. doi: 10.1523/ENEURO.0356-18.2019. eCollection 2019 Jan-Feb.


Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.

Zhao Y, Flandin P, Vogt D, Blood A, Hermesz E, Westphal H, Rubenstein JL.

Dev Biol. 2014 Jan 1;385(1):94-106. doi: 10.1016/j.ydbio.2013.10.010. Epub 2013 Oct 21.


Neural crest-specific deletion of Ldb1 leads to cleft secondary palate with impaired palatal shelf elevation.

Almaidhan A, Cesario J, Landin Malt A, Zhao Y, Sharma N, Choi V, Jeong J.

BMC Dev Biol. 2014 Jan 17;14:3. doi: 10.1186/1471-213X-14-3.


Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

Pratt T, Quinn JC, Simpson TI, West JD, Mason JO, Price DJ.

J Neurosci. 2002 Oct 1;22(19):8523-31.


Early thalamocortical tract guidance and topographic sorting of thalamic projections requires LIM-homeodomain gene Lhx2.

Lakhina V, Falnikar A, Bhatnagar L, Tole S.

Dev Biol. 2007 Jun 15;306(2):703-13. Epub 2007 Apr 14.


Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.

Hunter CS, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, Westphal H, Stein R, May CL.

Diabetes. 2013 Mar;62(3):875-86. doi: 10.2337/db12-0952. Epub 2012 Nov 27.


Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

Simpson TI, Pratt T, Mason JO, Price DJ.

Neural Dev. 2009 Jun 5;4:19. doi: 10.1186/1749-8104-4-19.


Disruption of Foxg1 expression by knock-in of cre recombinase: effects on the development of the mouse telencephalon.

Eagleson KL, Schlueter McFadyen-Ketchum LJ, Ahrens ET, Mills PH, Does MD, Nickols J, Levitt P.

Neuroscience. 2007 Aug 24;148(2):385-99. Epub 2007 Jul 19.


Defects in thalamocortical axon pathfinding correlate with altered cell domains in Mash-1-deficient mice.

Tuttle R, Nakagawa Y, Johnson JE, O'Leary DD.

Development. 1999 May;126(9):1903-16.


Ldb1- and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in the retina.

de Melo J, Clark BS, Venkataraman A, Shiau F, Zibetti C, Blackshaw S.

Development. 2018 Apr 30;145(9). pii: dev159970. doi: 10.1242/dev.159970.


Role of ldb1 in adult intestinal homeostasis.

Dey-Guha I, Mukhopadhyay M, Phillips M, Westphal H.

Int J Biol Sci. 2009 Oct 30;5(7):686-94.


A requirement for Lim domain binding protein 1 in erythropoiesis.

Li L, Lee JY, Gross J, Song SH, Dean A, Love PE.

J Exp Med. 2010 Nov 22;207(12):2543-50. doi: 10.1084/jem.20100504. Epub 2010 Nov 1.


SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes.

Galloway JR, Bethea M, Liu Y, Underwood R, Mobley JA, Hunter CS.

Mol Endocrinol. 2015 Dec;29(12):1774-86. doi: 10.1210/me.2015-1165. Epub 2015 Oct 23.


Ldb1 Is Essential for the Development of Isthmic Organizer and Midbrain Dopaminergic Neurons.

Kim S, Zhao Y, Lee JM, Kim WR, Gorivodsky M, Westphal H, Geum D.

Stem Cells Dev. 2016 Jul 1;25(13):986-94. doi: 10.1089/scd.2015.0307. Epub 2016 Jun 16.


The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.

Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R.

Development. 2016 Nov 15;143(22):4182-4192. Epub 2016 Oct 3.


LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.

Layer JH, Alford CE, McDonald WH, Davé UP.

Mol Cell Biol. 2015 Nov 23;36(3):488-506. doi: 10.1128/MCB.00901-15. Print 2016 Feb 1.


Gli3 is required for Emx gene expression during dorsal telencephalon development.

Theil T, Alvarez-Bolado G, Walter A, Rüther U.

Development. 1999 Aug;126(16):3561-71.


Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation.

Song SH, Kim A, Ragoczy T, Bender MA, Groudine M, Dean A.

Blood. 2010 Sep 30;116(13):2356-64. doi: 10.1182/blood-2010-03-272252. Epub 2010 Jun 22.


LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).

Simonik EA, Cai Y, Kimmelshue KN, Brantley-Sieders DM, Loomans HA, Andl CD, Westlake GM, Youngblood VM, Chen J, Yarbrough WG, Brown BT, Nagarajan L, Brandt SJ.

PLoS One. 2016 Oct 25;11(10):e0164804. doi: 10.1371/journal.pone.0164804. eCollection 2016.

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