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Characterization of the circulating microbiome in acute-on-chronic liver failure associated with hepatitis B.

Zhang Y, Zhao R, Shi D, Sun S, Ren H, Zhao H, Wu W, Jin L, Sheng J, Shi Y.

Liver Int. 2019 Mar 13. doi: 10.1111/liv.14097. [Epub ahead of print]


Characteristics of systemic inflammation in hepatitis B-precipitated ACLF: Differentiate it from No-ACLF.

Wu W, Yan H, Zhao H, Sun W, Yang Q, Sheng J, Shi Y.

Liver Int. 2018 Feb;38(2):248-257. doi: 10.1111/liv.13504. Epub 2017 Jul 18.


Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis.

Ren X, Xu Z, Liu Y, Li X, Bai S, Ding N, Zhong Y, Wang L, Mao P, Zoulim F, Xu D.

J Viral Hepat. 2010 Dec;17(12):887-95. doi: 10.1111/j.1365-2893.2009.01254.x.


[Analysis of the relationship between hepatitis B virus precore and basal core promoter mutations and acute-on-chronic liver failure].

Ma XY, Han T, Pei YZ, Zhao ZG, Gao YT, Li Y, Jing L.

Zhonghua Gan Zang Bing Za Zhi. 2012 Sep;20(9):644-8. doi: 10.3760/cma.j.issn.1007-3418.2012.09.002. Chinese.


Hepatitis B virus genotype B and mutations in basal core promoter and pre-core/core genes associated with acute-on-chronic liver failure: a multicenter cross-sectional study in China.

Yang G, Han M, Chen F, Xu Y, Chen E, Wang X, Liu Y, Sun J, Hou J, Ning Q, Wang Z.

Hepatol Int. 2014 Oct;8(4):508-16. doi: 10.1007/s12072-014-9554-4. Epub 2014 Jul 31.


The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis.

Puri P, Liangpunsakul S, Christensen JE, Shah VH, Kamath PS, Gores GJ, Walker S, Comerford M, Katz B, Borst A, Yu Q, Kumar DP, Mirshahi F, Radaeva S, Chalasani NP, Crabb DW, Sanyal AJ; TREAT Consortium.

Hepatology. 2018 Apr;67(4):1284-1302. doi: 10.1002/hep.29623. Epub 2018 Feb 22.


Altered PGE2-EP2 is associated with an excessive immune response in HBV-related acute-on-chronic liver failure.

Wang Y, Chen C, Qi J, Wu F, Guan J, Chen Z, Zhu H.

J Transl Med. 2019 Mar 19;17(1):93. doi: 10.1186/s12967-019-1844-0.


Systemic inflammation in decompensated cirrhosis: Characterization and role in acute-on-chronic liver failure.

Clària J, Stauber RE, Coenraad MJ, Moreau R, Jalan R, Pavesi M, Amorós À, Titos E, Alcaraz-Quiles J, Oettl K, Morales-Ruiz M, Angeli P, Domenicali M, Alessandria C, Gerbes A, Wendon J, Nevens F, Trebicka J, Laleman W, Saliba F, Welzel TM, Albillos A, Gustot T, Benten D, Durand F, Ginès P, Bernardi M, Arroyo V; CANONIC Study Investigators of the EASL-CLIF Consortium and the European Foundation for the Study of Chronic Liver Failure (EF-CLIF).

Hepatology. 2016 Oct;64(4):1249-64. doi: 10.1002/hep.28740. Epub 2016 Aug 25.


Increased CD4+CD25+ regulatory T cells correlate with poor short-term outcomes in hepatitis B virus-related acute-on-chronic liver failure patients.

Shen C, Yan WZ, Zhao CY, Che HH, Liu XY, Liu ZZ, Wang YD, Wang W, Li M, Gao J.

J Microbiol Immunol Infect. 2015 Apr;48(2):137-46. doi: 10.1016/j.jmii.2013.11.001. Epub 2013 Dec 31.


Gut dysbiosis in acute-on-chronic liver failure and its predictive value for mortality.

Chen Y, Guo J, Qian G, Fang D, Shi D, Guo L, Li L.

J Gastroenterol Hepatol. 2015 Sep;30(9):1429-37. doi: 10.1111/jgh.12932.


Interleukin-21 is upregulated in hepatitis B-related acute-on-chronic liver failure and associated with severity of liver disease.

Hu X, Ma S, Huang X, Jiang X, Zhu X, Gao H, Xu M, Sun J, Abbott WG, Hou J.

J Viral Hepat. 2011 Jul;18(7):458-67. doi: 10.1111/j.1365-2893.2011.01475.x. Epub 2011 Jun 1.


Association Between Intestinal Microbiota Collected at Hospital Admission and Outcomes of Patients With Cirrhosis.

Bajaj JS, Vargas HE, Reddy KR, Lai JC, O'Leary JG, Tandon P, Wong F, Mitrani R, White MB, Kelly M, Fagan A, Patil R, Sait S, Sikaroodi M, Thacker LR, Gillevet PM.

Clin Gastroenterol Hepatol. 2019 Mar;17(4):756-765.e3. doi: 10.1016/j.cgh.2018.07.022. Epub 2018 Jul 20.


Interleukin-1 receptor antagonist expression is inversely associated with outcomes of hepatitis B-related acute-on-chronic liver failure.

Lai J, Liu Y, Pan C, Lin C, Sun F, Huang Z, Lin Y, Zhou R, Lin Y, Zhou Y.

Exp Ther Med. 2017 Jun;13(6):2867-2875. doi: 10.3892/etm.2017.4361. Epub 2017 Apr 19.


Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation.

Li X, Gou C, Yao L, Lei Z, Gu T, Ren F, Wen T.

J Viral Hepat. 2017 Jan;24(1):59-67. doi: 10.1111/jvh.12612. Epub 2016 Sep 23.


Increased IL-17-producing CD8+ T cell frequency predicts short-term mortality in patients with hepatitis B virus-related acute-on-chronic liver failure.

Zhang GL, Zhang T, Zhao QY, Xie C, Lin CS, Gao ZL.

Ther Clin Risk Manag. 2018 Oct 30;14:2127-2136. doi: 10.2147/TCRM.S184809. eCollection 2018.


Serum levels of miRNA in patients with hepatitis B virus-associated acute-on-chronic liver failure.

Wen Y, Peng SF, Fu L, Fu XY, Wu DX, Liu BJ, Tan DM, Ouyang Y.

Hepatobiliary Pancreat Dis Int. 2018 Apr;17(2):126-132. doi: 10.1016/j.hbpd.2018.03.004. Epub 2018 Mar 13.


[Expression of COX-2 and PPARg in the livers of patients with acute on chronic HBV-related liver failure and their relationship with clinic parameters].

Niu YH, Yi RT, Liu HL, Chen TY, Zhang SL, Zhao YR.

Zhonghua Gan Zang Bing Za Zhi. 2011 Jul;19(7):511-6. doi: 10.3760/cma.j.issn.1007-3418.2011.07.011. Chinese.


Imbalance of interleukin-17-producing CD4 T cells/regulatory T cells axis occurs in remission stage of patients with hepatitis B virus-related acute-on-chronic liver failure.

Zhang GL, Xie DY, Lin BL, Xie C, Ye YN, Peng L, Zhang SQ, Zhang YF, Lai Q, Zhu JY, Zhang Y, Huang YS, Hu ZX, Gao ZL.

J Gastroenterol Hepatol. 2013 Mar;28(3):513-21. doi: 10.1111/jgh.12082.


Acute-on-chronic liver failure exists in patients with hepatitis B virus-related decompensated cirrhosis.

Wang SJ, Yin S, Gu WY, Zhang Y, Li H.

J Dig Dis. 2018 Oct;19(10):614-625. doi: 10.1111/1751-2980.12671.


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