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Items: 1 to 20 of 100

1.

High expression of SPAG5 sustains the malignant growth and invasion of breast cancer cells through the activation of Wnt/β-catenin signalling.

Jiang J, Wang J, He X, Ma W, Sun L, Zhou Q, Li M, Yu S.

Clin Exp Pharmacol Physiol. 2019 Mar 10. doi: 10.1111/1440-1681.13082. [Epub ahead of print]

PMID:
30854682
2.

SPAG5 contributes to the progression of gastric cancer by upregulation of Survivin depend on activating the wnt/β-catenin pathway.

Liu G, Liu S, Cao G, Luo W, Li P, Wang S, Chen Y.

Exp Cell Res. 2019 Jun 1;379(1):83-91. doi: 10.1016/j.yexcr.2019.03.024. Epub 2019 Mar 21.

PMID:
30904482
3.

SPAG5 promotes hepatocellular carcinoma progression by downregulating SCARA5 through modifying β-catenin degradation.

Liu H, Hu J, Wei R, Zhou L, Pan H, Zhu H, Huang M, Luo J, Xu W.

J Exp Clin Cancer Res. 2018 Sep 18;37(1):229. doi: 10.1186/s13046-018-0891-3.

4.

MicroRNA-449b-5p suppresses the growth and invasion of breast cancer cells via inhibiting CREPT-mediated Wnt/β-catenin signaling.

Jiang J, Yang X, He X, Ma W, Wang J, Zhou Q, Li M, Yu S.

Chem Biol Interact. 2019 Apr 1;302:74-82. doi: 10.1016/j.cbi.2019.02.004. Epub 2019 Feb 7.

PMID:
30738779
5.

MicroRNA-1179 suppresses cell growth and invasion by targeting sperm-associated antigen 5-mediated Akt signaling in human non-small cell lung cancer.

Song L, Dai Z, Zhang S, Zhang H, Liu C, Ma X, Liu D, Zan Y, Yin X.

Biochem Biophys Res Commun. 2018 Sep 26;504(1):164-170. doi: 10.1016/j.bbrc.2018.08.149. Epub 2018 Sep 1.

PMID:
30180955
6.

SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival.

Liu JY, Zeng QH, Cao PG, Xie D, Yang F, He LY, Dai YB, Li JJ, Liu XM, Zeng HL, Fan XJ, Liu L, Zhu YX, Gong L, Cheng Y, Zhou JD, Hu J, Bo H, Xu ZZ, Cao K.

Oncogene. 2018 Jul;37(29):3937-3952. doi: 10.1038/s41388-018-0223-2. Epub 2018 Apr 17.

PMID:
29662193
7.

Downregulated GBX2 gene suppresses proliferation, invasion and angiogenesis of breast cancer cells through inhibiting the Wnt/β-catenin signaling pathway.

Fang Y, Yuan Y, Zhang LL, Lu JW, Feng JF, Hu SN.

Cancer Biomark. 2018;23(3):405-418. doi: 10.3233/CBM-181466.

PMID:
30223390
8.

Downregulation of microRNA-532-5p promotes the proliferation and invasion of bladder cancer cells through promotion of HMGB3/Wnt/β-catenin signaling.

Xie X, Pan J, Han X, Chen W.

Chem Biol Interact. 2019 Feb 25;300:73-81. doi: 10.1016/j.cbi.2019.01.015. Epub 2019 Jan 11.

PMID:
30639441
9.

ATDC contributes to sustaining the growth and invasion of glioma cells through regulating Wnt/β-catenin signaling.

Cao Y, Shi L, Wang M, Hou J, Wei Y, Du C.

Chem Biol Interact. 2019 Mar 29;305:148-155. doi: 10.1016/j.cbi.2019.03.033. [Epub ahead of print]

PMID:
30929997
10.

Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells.

Wu Y, Ginther C, Kim J, Mosher N, Chung S, Slamon D, Vadgama JV.

Mol Cancer Res. 2012 Dec;10(12):1597-606. doi: 10.1158/1541-7786.MCR-12-0155-T. Epub 2012 Oct 15.

11.
12.

SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma.

Yang YF, Zhang MF, Tian QH, Fu J, Yang X, Zhang CZ, Yang H.

Mol Cancer. 2018 Aug 8;17(1):117. doi: 10.1186/s12943-018-0872-3.

13.

A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells.

Wu Y, Tran T, Dwabe S, Sarkissyan M, Kim J, Nava M, Clayton S, Pietras R, Farias-Eisner R, Vadgama JV.

Breast Cancer Res Treat. 2017 Jun;163(3):449-460. doi: 10.1007/s10549-017-4211-y. Epub 2017 Mar 23.

14.

Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer.

Lemieux E, Cagnol S, Beaudry K, Carrier J, Rivard N.

Oncogene. 2015 Sep 17;34(38):4914-27. doi: 10.1038/onc.2014.416. Epub 2014 Dec 15.

15.

Downregulation of microRNA-1469 promotes the development of breast cancer via targeting HOXA1 and activating PTEN/PI3K/AKT and Wnt/β-catenin pathways.

Zhang Y, Fang J, Zhao H, Yu Y, Cao X, Zhang B.

J Cell Biochem. 2019 Apr;120(4):5097-5107. doi: 10.1002/jcb.27786. Epub 2018 Oct 15.

PMID:
30320894
16.

MiR-454-3p-Mediated Wnt/β-catenin Signaling Antagonists Suppression Promotes Breast Cancer Metastasis.

Ren L, Chen H, Song J, Chen X, Lin C, Zhang X, Hou N, Pan J, Zhou Z, Wang L, Huang D, Yang J, Liang Y, Li J, Huang H, Jiang L.

Theranostics. 2019 Jan 1;9(2):449-465. doi: 10.7150/thno.29055. eCollection 2019.

17.

Benzyl isothiocyanate inhibits breast cancer cell tumorigenesis via repression of the FoxH1-Mediated Wnt/β-catenin pathway.

Liu Y, Zhang L, Meng Y, Huang L.

Int J Clin Exp Med. 2015 Oct 15;8(10):17601-11. eCollection 2015.

18.

Capn4 expression is modulated by microRNA-520b and exerts an oncogenic role in prostate cancer cells by promoting Wnt/β-catenin signaling.

Ren W, Wang D, Li C, Shu T, Zhang W, Fu X.

Biomed Pharmacother. 2018 Dec;108:467-475. doi: 10.1016/j.biopha.2018.09.019. Epub 2018 Sep 18.

19.

Overexpressed ACBD3 has prognostic value in human breast cancer and promotes the self-renewal potential of breast cancer cells by activating the Wnt/beta-catenin signaling pathway.

Huang Y, Yang L, Pei YY, Wang J, Wu H, Yuan J, Wang L.

Exp Cell Res. 2018 Feb 1;363(1):39-47. doi: 10.1016/j.yexcr.2018.01.003. Epub 2018 Jan 4.

PMID:
29307786
20.

MicroRNA-504 functions as a tumor suppressor in hepatocellular carcinoma through inhibiting Frizzled-7-mediated-Wnt/β-catenin signaling.

Quan H, Li B, Yang J.

Biomed Pharmacother. 2018 Nov;107:754-762. doi: 10.1016/j.biopha.2018.07.150. Epub 2018 Aug 21.

PMID:
30142536

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