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Items: 1 to 20 of 102

1.

A Novel Pentapeptide Inhibitor Reduces Amyloid Deposit Formation by Direct Interaction with hIAPP.

Shi Y, Lv W, Jiao A, Zhang C, Zhang J.

Int J Endocrinol. 2019 Jan 29;2019:9062032. doi: 10.1155/2019/9062032. eCollection 2019.

2.

Interaction of hIAPP with model raft membranes and pancreatic beta-cells: cytotoxicity of hIAPP oligomers.

Weise K, Radovan D, Gohlke A, Opitz N, Winter R.

Chembiochem. 2010 Jun 14;11(9):1280-90. doi: 10.1002/cbic.201000039.

PMID:
20440729
3.

Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties.

Tenidis K, Waldner M, Bernhagen J, Fischle W, Bergmann M, Weber M, Merkle ML, Voelter W, Brunner H, Kapurniotu A.

J Mol Biol. 2000 Jan 28;295(4):1055-71.

PMID:
10656810
4.

Genistein: A Dual Inhibitor of Both Amyloid β and Human Islet Amylin Peptides.

Ren B, Liu Y, Zhang Y, Cai Y, Gong X, Chang Y, Xu L, Zheng J.

ACS Chem Neurosci. 2018 May 16;9(5):1215-1224. doi: 10.1021/acschemneuro.8b00039. Epub 2018 Feb 20.

PMID:
29432676
5.
6.

Fluorine Functionalized Graphene Quantum Dots as Inhibitor against hIAPP Amyloid Aggregation.

Yousaf M, Huang H, Li P, Wang C, Yang Y.

ACS Chem Neurosci. 2017 Jun 21;8(6):1368-1377. doi: 10.1021/acschemneuro.7b00015. Epub 2017 Mar 3.

PMID:
28230965
7.

Combined in silico approaches for the identification of novel inhibitors of human islet amyloid polypeptide (hIAPP) fibrillation.

Patel P, Parmar K, Vyas VK, Patel D, Das M.

J Mol Graph Model. 2017 Oct;77:295-310. doi: 10.1016/j.jmgm.2017.09.004. Epub 2017 Sep 6.

PMID:
28917147
8.

Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors.

Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS.

J Biol Chem. 2018 Feb 23;293(8):2888-2902. doi: 10.1074/jbc.M117.806109. Epub 2017 Dec 27.

9.

Structural studies and cytotoxicity assays of "aggregation-prone" IAPP(8-16) and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin.

Louros NN, Tsiolaki PL, Zompra AA, Pappa EV, Magafa V, Pairas G, Cordopatis P, Cheimonidou C, Trougakos IP, Iconomidou VA, Hamodrakas SJ.

Biopolymers. 2015 May;104(3):196-205. doi: 10.1002/bip.22650.

PMID:
25913357
10.
11.

Recent computational studies of membrane interaction and disruption of human islet amyloid polypeptide: Monomers, oligomers and protofibrils.

Dong X, Qiao Q, Qian Z, Wei G.

Biochim Biophys Acta Biomembr. 2018 Mar 10. pii: S0005-2736(18)30086-5. doi: 10.1016/j.bbamem.2018.03.006. [Epub ahead of print] Review.

PMID:
29530482
12.

Peptide Conjugates of Benzene Carboxylic Acids as Agonists and Antagonists of Amylin Aggregation.

Profit AA, Vedad J, Desamero RZ.

Bioconjug Chem. 2017 Feb 15;28(2):666-677. doi: 10.1021/acs.bioconjchem.6b00732. Epub 2017 Jan 27.

13.

Inhibition of hIAPP Amyloid Aggregation and Pancreatic β-Cell Toxicity by OH-Terminated PAMAM Dendrimer.

Gurzov EN, Wang B, Pilkington EH, Chen P, Kakinen A, Stanley WJ, Litwak SA, Hanssen EG, Davis TP, Ding F, Ke PC.

Small. 2016 Mar 23;12(12):1615-26. doi: 10.1002/smll.201502317. Epub 2016 Jan 25.

14.

Molecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes Mellitus.

Caillon L, Hoffmann AR, Botz A, Khemtemourian L.

J Diabetes Res. 2016;2016:5639875. doi: 10.1155/2016/5639875. Epub 2015 Nov 9. Review.

15.
16.

New insights into side effect of solvents on the aggregation of human islet amyloid polypeptide 11-20.

Mao Y, Yu L, Yang R, Ma C, Qu LB, Harrington Pde B.

Talanta. 2016 Feb 1;148:380-6. doi: 10.1016/j.talanta.2015.11.012. Epub 2015 Nov 6.

PMID:
26653463
17.

Cross-sequence interactions between human and rat islet amyloid polypeptides.

Hu R, Zhang M, Patel K, Wang Q, Chang Y, Gong X, Zhang G, Zheng J.

Langmuir. 2014 May 13;30(18):5193-201. doi: 10.1021/la500632d. Epub 2014 May 1.

PMID:
24754490
18.

Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane damage in vitro.

Khemtémourian L, Lahoz Casarramona G, Suylen DP, Hackeng TM, Meeldijk JD, de Kruijff B, Höppener JW, Killian JA.

Biochemistry. 2009 Nov 24;48(46):10918-25. doi: 10.1021/bi901076d.

PMID:
19817482
19.

Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes.

Gong H, Zhang X, Cheng B, Sun Y, Li C, Li T, Zheng L, Huang K.

PLoS One. 2013;8(1):e54198. doi: 10.1371/journal.pone.0054198. Epub 2013 Jan 23.

20.

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane.

Engel MF, Khemtémourian L, Kleijer CC, Meeldijk HJ, Jacobs J, Verkleij AJ, de Kruijff B, Killian JA, Höppener JW.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6033-8. doi: 10.1073/pnas.0708354105. Epub 2008 Apr 11.

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