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Items: 1 to 20 of 101

1.

Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.

Choi W, Villegas V, Istre H, Heppler B, Gonzalez N, Brusman N, Snider L, Hogle E, Tucker J, Oñate A, Oñate S, Ma L, Paula S.

Bioorg Chem. 2019 May;86:686-695. doi: 10.1016/j.bioorg.2019.02.049. Epub 2019 Feb 22.

PMID:
30831530
2.

Structure-activity relationship of C6-C3 phenylpropanoids on xanthine oxidase-inhibiting and free radical-scavenging activities.

Chang YC, Lee FW, Chen CS, Huang ST, Tsai SH, Huang SH, Lin CM.

Free Radic Biol Med. 2007 Dec 1;43(11):1541-51. Epub 2007 Sep 4.

PMID:
17964425
3.

Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers.

Hofmann E, Webster J, Do T, Kline R, Snider L, Hauser Q, Higginbottom G, Campbell A, Ma L, Paula S.

Bioorg Med Chem. 2016 Feb 15;24(4):578-87. doi: 10.1016/j.bmc.2015.12.024. Epub 2015 Dec 17.

4.

Structure-activity relationship of coumarin derivatives on xanthine oxidase-inhibiting and free radical-scavenging activities.

Lin HC, Tsai SH, Chen CS, Chang YC, Lee CM, Lai ZY, Lin CM.

Biochem Pharmacol. 2008 Mar 15;75(6):1416-25. doi: 10.1016/j.bcp.2007.11.023. Epub 2007 Dec 15.

PMID:
18201686
5.

Synthesis, structure-activity relationships, and mechanistic studies of 5-arylazo-tropolone derivatives as novel xanthine oxidase (XO) inhibitors.

Sato D, Kisen T, Kumagai M, Ohta K.

Bioorg Med Chem. 2018 Jan 15;26(2):536-542. doi: 10.1016/j.bmc.2017.12.017. Epub 2017 Dec 13.

PMID:
29274704
6.

Synthesis and evaluation of xanthine oxidase inhibitory and antioxidant activities of 2-arylbenzo[b]furan derivatives based on salvianolic acid C.

Tang HJ, Zhang XW, Yang L, Li W, Li JH, Wang JX, Chen J.

Eur J Med Chem. 2016 Nov 29;124:637-648. doi: 10.1016/j.ejmech.2016.08.019. Epub 2016 Aug 31.

PMID:
27614410
7.

Role of xanthine oxidase inhibitor as free radical scavenger: a novel mechanism of action of allopurinol and oxypurinol in myocardial salvage.

Das DK, Engelman RM, Clement R, Otani H, Prasad MR, Rao PS.

Biochem Biophys Res Commun. 1987 Oct 14;148(1):314-9. Erratum in: Biochem Biophys Res Commun 1987 Nov 13;148(3):1550.

PMID:
2823807
8.

Characterization of the xanthine oxidase inhibitory activity of alk(en)yl phenols and related compounds.

Masuoka N, Kubo I.

Phytochemistry. 2018 Nov;155:100-106. doi: 10.1016/j.phytochem.2018.07.006. Epub 2018 Jul 23. Review.

PMID:
30096514
9.

Preconditioning-induced neuroprotection is mediated by reactive oxygen species.

Ravati A, Ahlemeyer B, Becker A, Krieglstein J.

Brain Res. 2000 Jun 2;866(1-2):23-32.

PMID:
10825477
10.

Hydrophilic ester-bearing chlorogenic acid binds to a novel domain to inhibit xanthine oxidase.

Wang SH, Chen CS, Huang SH, Yu SH, Lai ZY, Huang ST, Lin CM.

Planta Med. 2009 Sep;75(11):1237-40. doi: 10.1055/s-0029-1185521. Epub 2009 Mar 27.

PMID:
19330765
11.

6-(N-benzoylamino)purine as a novel and potent inhibitor of xanthine oxidase: inhibition mechanism and molecular modeling studies.

Tamta H, Thilagavathi R, Chakraborti AK, Mukhopadhyay AK.

J Enzyme Inhib Med Chem. 2005 Aug;20(4):317-24.

PMID:
16206825
12.

Deciphering the inhibitory mechanism of genistein on xanthine oxidase in vitro.

Lin S, Zhang G, Pan J, Gong D.

J Photochem Photobiol B. 2015 Dec;153:463-72. doi: 10.1016/j.jphotobiol.2015.10.022. Epub 2015 Nov 11.

PMID:
26584360
13.

Synthesis, antioxidant, and xanthine oxidase inhibitory activities of 5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione derivatives.

Begum AB, Begum M, Ranganatha VL, Prashanth T, Zameer F, Hegdekatte R, Khanum SA.

Arch Pharm (Weinheim). 2014 Apr;347(4):247-55. doi: 10.1002/ardp.201300319. Epub 2013 Dec 16.

PMID:
24343903
14.

Suppression of superoxide anion generation catalyzed by xanthine oxidase with alkyl caffeates and the scavenging activity.

Masuoka N, Kubo I.

Int J Food Sci Nutr. 2016;67(3):283-7. doi: 10.3109/09637486.2016.1153609. Epub 2016 Mar 3.

PMID:
26940252
15.

Development of 2-(Substituted Benzylamino)-4-Methyl-1, 3-Thiazole-5-Carboxylic Acid Derivatives as Xanthine Oxidase Inhibitors and Free Radical Scavengers.

Ali MR, Kumar S, Afzal O, Shalmali N, Sharma M, Bawa S.

Chem Biol Drug Des. 2016 Apr;87(4):508-16. doi: 10.1111/cbdd.12686. Epub 2015 Dec 16.

PMID:
26575582
16.

Synthesis and xanthine oxidase inhibitory activity of 5,6-dihydropyrazolo/pyrazolo[1,5-c]quinazoline derivatives.

Kumar D, Kaur G, Negi A, Kumar S, Singh S, Kumar R.

Bioorg Chem. 2014 Dec;57:57-64. doi: 10.1016/j.bioorg.2014.08.007. Epub 2014 Aug 30.

PMID:
25222504
17.

Protective effects of caffeic acid phenethyl ester on skeletal muscle ischemia-reperfusion injury in rats.

Ozyurt B, Iraz M, Koca K, Ozyurt H, Sahin S.

Mol Cell Biochem. 2006 Nov;292(1-2):197-203. Epub 2006 Jun 20.

PMID:
16786192
18.

Identification of a potent xanthine oxidase inhibitor from oxidation of caffeic acid.

Masuda T, Shingai Y, Takahashi C, Inai M, Miura Y, Honda S, Masuda A.

Free Radic Biol Med. 2014 Apr;69:300-7. doi: 10.1016/j.freeradbiomed.2014.01.016. Epub 2014 Feb 3.

PMID:
24503177
19.

Inhibition of chrysin on xanthine oxidase activity and its inhibition mechanism.

Lin S, Zhang G, Liao Y, Pan J.

Int J Biol Macromol. 2015 Nov;81:274-82. doi: 10.1016/j.ijbiomac.2015.08.017. Epub 2015 Aug 11.

PMID:
26275460
20.

Design and synthesis of novel 2-(indol-5-yl)thiazole derivatives as xanthine oxidase inhibitors.

Song JU, Choi SP, Kim TH, Jung CK, Lee JY, Jung SH, Kim GT.

Bioorg Med Chem Lett. 2015 Mar 15;25(6):1254-8. doi: 10.1016/j.bmcl.2015.01.055. Epub 2015 Jan 30.

PMID:
25704891

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