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Items: 1 to 20 of 101

1.

GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca2+ signalling in a GABA-independent manner.

Jiang SH, Zhu LL, Zhang M, Li RK, Yang Q, Yan JY, Zhang C, Yang JY, Dong FY, Dai M, Hu LP, Li J, Li Q, Wang YH, Yang XM, Zhang YL, Nie HZ, Zhu L, Zhang XL, Tian GA, Zhang XX, Cao XY, Tao LY, Huang S, Jiang YS, Hua R, Qian Luo K, Gu JR, Sun YW, Hou S, Zhang ZG.

Gut. 2019 Mar 2. pii: gutjnl-2018-317479. doi: 10.1136/gutjnl-2018-317479. [Epub ahead of print]

PMID:
30826748
2.

Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.

Takehara A, Hosokawa M, Eguchi H, Ohigashi H, Ishikawa O, Nakamura Y, Nakagawa H.

Cancer Res. 2007 Oct 15;67(20):9704-12.

3.

Integrated expression profiling of potassium channels identifys KCNN4 as a prognostic biomarker of pancreatic cancer.

Jiang S, Zhu L, Yang J, Hu L, Gu J, Xing X, Sun Y, Zhang Z.

Biochem Biophys Res Commun. 2017 Dec 9;494(1-2):113-119. doi: 10.1016/j.bbrc.2017.10.072. Epub 2017 Oct 16.

PMID:
29050937
4.

Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice.

Huang C, Li Z, Li N, Li Y, Chang A, Zhao T, Wang X, Wang H, Gao S, Yang S, Hao J, Ren H.

Gastroenterology. 2018 Feb;154(3):675-688. doi: 10.1053/j.gastro.2017.09.039. Epub 2017 Oct 6.

PMID:
28989066
5.

Systematic characterisation of GABRP expression in sporadic breast cancer and normal breast tissue.

Zafrakas M, Chorovicer M, Klaman I, Kristiansen G, Wild PJ, Heindrichs U, Knüchel R, Dahl E.

Int J Cancer. 2006 Mar 15;118(6):1453-9.

6.

GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia.

Lu J, Zhang Q, Tan D, Luo W, Zhao H, Ma J, Liang H, Tan Y.

Int J Mol Med. 2016 Jul;38(1):105-12. doi: 10.3892/ijmm.2016.2608. Epub 2016 May 25.

7.

Expression of DRD2 Is Increased in Human Pancreatic Ductal Adenocarcinoma and Inhibitors Slow Tumor Growth in Mice.

Jandaghi P, Najafabadi HS, Bauer AS, Papadakis AI, Fassan M, Hall A, Monast A, von Knebel Doeberitz M, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Sipos B, Auld D, Lathrop M, Park M, Büchler MW, Strobel O, Hackert T, Giese NA, Zogopoulos G, Sangwan V, Huang S, Riazalhosseini Y, Hoheisel JD.

Gastroenterology. 2016 Dec;151(6):1218-1231. doi: 10.1053/j.gastro.2016.08.040. Epub 2016 Aug 28.

PMID:
27578530
8.

Aberrant epigenetic regulation of GABRP associates with aggressive phenotype of ovarian cancer.

Sung HY, Yang SD, Ju W, Ahn JH.

Exp Mol Med. 2017 May 19;49(5):e335. doi: 10.1038/emm.2017.62.

9.

Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice.

Jiang SH, Li J, Dong FY, Yang JY, Liu DJ, Yang XM, Wang YH, Yang MW, Fu XL, Zhang XX, Li Q, Pang XF, Huo YM, Li J, Zhang JF, Lee HY, Lee SJ, Qin WX, Gu JR, Sun YW, Zhang ZG.

Gastroenterology. 2017 Jul;153(1):277-291.e19. doi: 10.1053/j.gastro.2017.03.008. Epub 2017 Mar 15.

PMID:
28315323
10.

SOX9 regulates ERBB signalling in pancreatic cancer development.

Grimont A, Pinho AV, Cowley MJ, Augereau C, Mawson A, Giry-Laterrière M, Van den Steen G, Waddell N, Pajic M, Sempoux C, Wu J, Grimmond SM, Biankin AV, Lemaigre FP, Rooman I, Jacquemin P.

Gut. 2015 Nov;64(11):1790-9. doi: 10.1136/gutjnl-2014-307075. Epub 2014 Oct 21.

PMID:
25336113
11.

Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma.

Xie Y, Zhu S, Zhong M, Yang M, Sun X, Liu J, Kroemer G, Lotze M, Zeh HJ 3rd, Kang R, Tang D.

Gastroenterology. 2017 Nov;153(5):1429-1443.e5. doi: 10.1053/j.gastro.2017.07.036. Epub 2017 Jul 29.

12.

Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer.

Geismann C, Grohmann F, Dreher A, Häsler R, Rosenstiel P, Legler K, Hauser C, Egberts JH, Sipos B, Schreiber S, Linkermann A, Hassan Z, Schneider G, Schäfer H, Arlt A.

Biochim Biophys Acta Mol Cell Res. 2017 May;1864(5):782-796. doi: 10.1016/j.bbamcr.2017.02.005. Epub 2017 Feb 8.

13.

GABA(A) receptor pi (GABRP) stimulates basal-like breast cancer cell migration through activation of extracellular-regulated kinase 1/2 (ERK1/2).

Sizemore GM, Sizemore ST, Seachrist DD, Keri RA.

J Biol Chem. 2014 Aug 29;289(35):24102-13. doi: 10.1074/jbc.M114.593582. Epub 2014 Jul 10.

14.

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine.

Ferro R, Adamska A, Lattanzio R, Mavrommati I, Edling CE, Arifin SA, Fyffe CA, Sala G, Sacchetto L, Chiorino G, De Laurenzi V, Piantelli M, Sansom OJ, Maffucci T, Falasca M.

Oncogene. 2018 Dec;37(49):6368-6382. doi: 10.1038/s41388-018-0390-1. Epub 2018 Jul 30.

PMID:
30061636
15.

Small Nucleolar Noncoding RNA SNORA23, Up-Regulated in Human Pancreatic Ductal Adenocarcinoma, Regulates Expression of Spectrin Repeat-Containing Nuclear Envelope 2 to Promote Growth and Metastasis of Xenograft Tumors in Mice.

Cui L, Nakano K, Obchoei S, Setoguchi K, Matsumoto M, Yamamoto T, Obika S, Shimada K, Hiraoka N.

Gastroenterology. 2017 Jul;153(1):292-306.e2. doi: 10.1053/j.gastro.2017.03.050. Epub 2017 Apr 5.

PMID:
28390868
16.

Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.

Chalabi-Dchar M, Cassant-Sourdy S, Duluc C, Fanjul M, Lulka H, Samain R, Roche C, Breibach F, Delisle MB, Poupot M, Dufresne M, Shimaoka T, Yonehara S, Mathonnet M, Pyronnet S, Bousquet C.

Gastroenterology. 2015 Jun;148(7):1452-65. doi: 10.1053/j.gastro.2015.02.009. Epub 2015 Feb 13.

PMID:
25683115
17.

Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice.

Al-Wadei HA, Al-Wadei MH, Ullah MF, Schuller HM.

PLoS One. 2012;7(8):e43376. doi: 10.1371/journal.pone.0043376. Epub 2012 Aug 16.

18.

miRNA-1290 Promotes Aggressiveness in Pancreatic Ductal Adenocarcinoma by Targeting IKK1.

Ta N, Huang X, Zheng K, Zhang Y, Gao Y, Deng L, Zhang B, Jiang H, Zheng J.

Cell Physiol Biochem. 2018;51(2):711-728. doi: 10.1159/000495328. Epub 2018 Nov 21.

19.

Early expression of the fractalkine receptor CX3CR1 in pancreatic carcinogenesis.

Celesti G, Di Caro G, Bianchi P, Grizzi F, Marchesi F, Basso G, Rahal D, Delconte G, Catalano M, Cappello P, Roncalli M, Zerbi A, Montorsi M, Novelli F, Mantovani A, Allavena P, Malesci A, Laghi L.

Br J Cancer. 2013 Oct 29;109(9):2424-33. doi: 10.1038/bjc.2013.565. Epub 2013 Oct 1.

20.

MicroRNA-29b-2-5p inhibits cell proliferation by directly targeting Cbl-b in pancreatic ductal adenocarcinoma.

Li C, Dong Q, Che X, Xu L, Li Z, Fan Y, Hou K, Wang S, Qu J, Xu L, Wen T, Yang X, Qu X, Liu Y.

BMC Cancer. 2018 Jun 25;18(1):681. doi: 10.1186/s12885-018-4526-z.

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