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Dynamic changes in lung responses after single and repeated exposures to cigarette smoke in mice.

Engle ML, Monk JN, Jania CM, Martin JR, Gomez JC, Dang H, Parker JS, Doerschuk CM.

PLoS One. 2019 Feb 28;14(2):e0212866. doi: 10.1371/journal.pone.0212866. eCollection 2019.


Gene expression in the lung of p53 mutant mice exposed to cigarette smoke.

Izzotti A, Cartiglia C, Longobardi M, Bagnasco M, Merello A, You M, Lubet RA, De Flora S.

Cancer Res. 2004 Dec 1;64(23):8566-72.


Exposure to cigarette smoke during pregnancy causes redox imbalance and histological damage in lung tissue of neonatal mice.

Campos KK, Dourado VA, Diniz MF, Bezerra FS, Lima WG.

Exp Lung Res. 2014 Apr;40(4):164-71. doi: 10.3109/01902148.2014.893383. Epub 2014 Mar 26.


The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes.

Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schüller J, Xu H, Taguchi K, Yamamoto M, Müller T.

Toxicol Sci. 2010 May;115(1):238-52. doi: 10.1093/toxsci/kfq039. Epub 2010 Feb 4.


Inhaled cigarette smoke induces the formation of DNA adducts in lungs of rats.

Bond JA, Chen BT, Griffith WC, Mauderly JL.

Toxicol Appl Pharmacol. 1989 Jun 1;99(1):161-72.


Tocopherol transfer protein deficiency modifies nuclear receptor transcriptional networks in lungs: modulation by cigarette smoke in vivo.

Gohil K, Oommen S, Vasu VT, Aung HH, Cross CE.

Mol Aspects Med. 2007 Oct-Dec;28(5-6):453-80. Epub 2007 Feb 24.


Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice.

Vlahos R, Bozinovski S, Jones JE, Powell J, Gras J, Lilja A, Hansen MJ, Gualano RC, Irving L, Anderson GP.

Am J Physiol Lung Cell Mol Physiol. 2006 May;290(5):L931-45. Epub 2005 Dec 16.


Gene expression profiling in lung tissues from mice exposed to cigarette smoke, lipopolysaccharide, or smoke plus lipopolysaccharide by inhalation.

Meng QR, Gideon KM, Harbo SJ, Renne RA, Lee MK, Brys AM, Jones R.

Inhal Toxicol. 2006 Jul;18(8):555-68.


Long-term nose-only cigarette smoke exposure induces emphysema and mild skeletal muscle dysfunction in mice.

Rinaldi M, Maes K, De Vleeschauwer S, Thomas D, Verbeken EK, Decramer M, Janssens W, Gayan-Ramirez GN.

Dis Model Mech. 2012 May;5(3):333-41. doi: 10.1242/dmm.008508. Epub 2012 Jan 25.


Acute exposure to waterpipe tobacco smoke induces changes in the oxidative and inflammatory markers in mouse lung.

Khabour OF, Alzoubi KH, Bani-Ahmad M, Dodin A, Eissenberg T, Shihadeh A.

Inhal Toxicol. 2012 Aug;24(10):667-75. doi: 10.3109/08958378.2012.710918.


Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke.

Didon L, Barton JL, Roos AB, Gaschler GJ, Bauer CM, Berg T, Stämpfli MR, Nord M.

Am J Respir Crit Care Med. 2011 Jul 15;184(2):233-42. doi: 10.1164/rccm.201007-1113OC. Epub 2011 May 11.


Inhibition of interleukin-1beta reduces mouse lung inflammation induced by exposure to cigarette smoke.

Castro P, Legora-Machado A, Cardilo-Reis L, Valença S, Porto LC, Walker C, Zuany-Amorim C, Koatz VL.

Eur J Pharmacol. 2004 Sep 13;498(1-3):279-86.


Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process.

Geraghty P, Wallace A, D'Armiento JM.

Int J Chron Obstruct Pulmon Dis. 2011;6:309-19. doi: 10.2147/COPD.S19599. Epub 2011 Jun 2.


Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes.

van Eijl S, Mortaz E, Ferreira AF, Kuper F, Nijkamp FP, Folkerts G, Bloksma N.

Pulm Pharmacol Ther. 2011 Dec;24(6):682-9. doi: 10.1016/j.pupt.2011.07.001. Epub 2011 Jul 24.


Anti-malarial drug artesunate protects against cigarette smoke-induced lung injury in mice.

Ng DS, Liao W, Tan WS, Chan TK, Loh XY, Wong WS.

Phytomedicine. 2014 Oct 15;21(12):1638-44. doi: 10.1016/j.phymed.2014.07.018. Epub 2014 Sep 1.


Exposure to cigarette smoke upregulates AP-1 activity and induces TNF-alpha overexpression in mouse lungs.

Li YT, He B, Wang YZ.

Inhal Toxicol. 2009 Jun;21(7):641-7. doi: 10.1080/08958370802322596.


Gene Profiles in a Smoke-Induced COPD Mouse Lung Model Following Treatment with Mesenchymal Stem Cells.

Kim YS, Kokturk N, Kim JY, Lee SW, Lim J, Choi SJ, Oh W, Oh YM.

Mol Cells. 2016 Oct;39(10):728-733. Epub 2016 Oct 31.


Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation.

Braber S, Henricks PA, Nijkamp FP, Kraneveld AD, Folkerts G.

Respir Res. 2010 Jul 22;11:99. doi: 10.1186/1465-9921-11-99.


Neu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammation.

Thatcher TH, Hsiao HM, Pinner E, Laudon M, Pollock SJ, Sime PJ, Phipps RP.

Am J Physiol Lung Cell Mol Physiol. 2013 Jul 15;305(2):L165-74. doi: 10.1152/ajplung.00036.2013. Epub 2013 May 17.


Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke.

De Flora S, Balansky RM, D'Agostini F, Izzotti A, Camoirano A, Bennicelli C, Zhang Z, Wang Y, Lubet RA, You M.

Cancer Res. 2003 Feb 15;63(4):793-800.

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