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Items: 1 to 20 of 103

1.

STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion.

Zhang CX, Ye SB, Ni JJ, Cai TT, Liu YN, Huang DJ, Mai HQ, Chen QY, He J, Zhang XS, Zeng YX, Li J, Cui J.

Cell Death Differ. 2019 Feb 28. doi: 10.1038/s41418-019-0302-0. [Epub ahead of print]

PMID:
30816302
2.

STAT3 inhibition enhances CDN-induced STING signaling and antitumor immunity.

Pei J, Zhang Y, Luo Q, Zheng W, Li W, Zeng X, Li Q, Quan J.

Cancer Lett. 2019 May 28;450:110-122. doi: 10.1016/j.canlet.2019.02.029. Epub 2019 Feb 18.

3.

LMP1-mediated glycolysis induces myeloid-derived suppressor cell expansion in nasopharyngeal carcinoma.

Cai TT, Ye SB, Liu YN, He J, Chen QY, Mai HQ, Zhang CX, Cui J, Zhang XS, Busson P, Zeng YX, Li J.

PLoS Pathog. 2017 Jul 21;13(7):e1006503. doi: 10.1371/journal.ppat.1006503. eCollection 2017 Jul.

4.

Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cells.

Xiao P, Wan X, Cui B, Liu Y, Qiu C, Rong J, Zheng M, Song Y, Chen L, He J, Tan Q, Wang X, Shao X, Liu Y, Cao X, Wang Q.

Oncoimmunology. 2015 Jun 24;5(1):e1063772. eCollection 2016.

5.

COX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells.

Li ZL, Ye SB, OuYang LY, Zhang H, Chen YS, He J, Chen QY, Qian CN, Zhang XS, Cui J, Zeng YX, Li J.

Oncoimmunology. 2015 Jul 9;4(11):e1044712. eCollection 2015 Nov.

6.

Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases.

Thorn M, Guha P, Cunetta M, Espat NJ, Miller G, Junghans RP, Katz SC.

Cancer Gene Ther. 2016 Jun;23(6):188-98. doi: 10.1038/cgt.2016.19. Epub 2016 May 20.

PMID:
27199222
7.

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation.

Lemos H, Mohamed E, Huang L, Ou R, Pacholczyk G, Arbab AS, Munn D, Mellor AL.

Cancer Res. 2016 Apr 15;76(8):2076-81. doi: 10.1158/0008-5472.CAN-15-1456. Epub 2016 Mar 10.

8.

STING Signaling in Cancer Cells: Important or Not?

Sokolowska O, Nowis D.

Arch Immunol Ther Exp (Warsz). 2018 Apr;66(2):125-132. doi: 10.1007/s00005-017-0481-7. Epub 2017 Jul 26. Review.

9.

Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways.

Liu Y, Li J, Chen J, Li Y, Wang W, Du X, Song W, Zhang W, Lin L, Yuan Z.

J Virol. 2015 Feb;89(4):2287-300. doi: 10.1128/JVI.02760-14. Epub 2014 Dec 10.

10.

MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy.

Finke J, Ko J, Rini B, Rayman P, Ireland J, Cohen P.

Int Immunopharmacol. 2011 Jul;11(7):856-61. doi: 10.1016/j.intimp.2011.01.030. Epub 2011 Feb 11.

11.

Interferon-γ and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).

Souza-Fonseca-Guimaraes F, Parlato M, de Oliveira RB, Golenbock D, Fitzgerald K, Shalova IN, Biswas SK, Cavaillon JM, Adib-Conquy M.

J Biol Chem. 2013 Apr 12;288(15):10715-21. doi: 10.1074/jbc.M112.435602. Epub 2013 Feb 26.

12.

SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells.

Yu H, Liu Y, McFarland BC, Deshane JS, Hurst DR, Ponnazhagan S, Benveniste EN, Qin H.

Cancer Immunol Res. 2015 Jul;3(7):727-40. doi: 10.1158/2326-6066.CIR-15-0004. Epub 2015 Feb 3.

13.

Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells.

Deng Y, Cheng J, Fu B, Liu W, Chen G, Zhang Q, Yang Y.

Oncogene. 2017 Feb 23;36(8):1090-1101. doi: 10.1038/onc.2016.273. Epub 2016 Sep 5.

PMID:
27593937
14.
15.

IL-17 inhibits the accumulation of myeloid-derived suppressor cells in breast cancer via activating STAT3.

Ma M, Huang W, Kong D.

Int Immunopharmacol. 2018 Jun;59:148-156. doi: 10.1016/j.intimp.2018.04.013. Epub 2018 Apr 11.

PMID:
29655056
16.

Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function.

Nam S, Kang K, Cha JS, Kim JW, Lee HG, Kim Y, Yang Y, Lee MS, Lim JS.

J Leukoc Biol. 2016 Dec;100(6):1273-1284. Epub 2016 Sep 6.

PMID:
27601624
17.

SPLUNC1 reduces the inflammatory response of nasopharyngeal carcinoma cells infected with the EB virus by inhibiting the TLR9/NF-κB pathway.

Ou C, Sun Z, Zhang H, Xiong W, Ma J, Zhou M, Lu J, Zeng Z, Bo X, Chen P, Li G, Li X, Li X.

Oncol Rep. 2015 Jun;33(6):2779-88. doi: 10.3892/or.2015.3913. Epub 2015 Apr 17.

PMID:
25891128
18.

STING-mediated DNA sensing in cancer immunotherapy.

Zhou X, Jiang Z.

Sci China Life Sci. 2017 Jun;60(6):563-574. doi: 10.1007/s11427-016-9066-0. Epub 2017 May 29. Review.

PMID:
28639100
19.

STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment.

Ohkuri T, Ghosh A, Kosaka A, Zhu J, Ikeura M, David M, Watkins SC, Sarkar SN, Okada H.

Cancer Immunol Res. 2014 Dec;2(12):1199-208. doi: 10.1158/2326-6066.CIR-14-0099. Epub 2014 Oct 9.

20.

Host STING-dependent MDSC mobilization drives extrinsic radiation resistance.

Liang H, Deng L, Hou Y, Meng X, Huang X, Rao E, Zheng W, Mauceri H, Mack M, Xu M, Fu YX, Weichselbaum RR.

Nat Commun. 2017 Nov 23;8(1):1736. doi: 10.1038/s41467-017-01566-5.

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