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Items: 1 to 20 of 99

1.

Reading Conformational Changes in Proteins with a New Colloidal-Based Interfacial Biosensing System.

Ahmed M, Carrascosa LG, Mainwaring P, Trau M.

ACS Appl Mater Interfaces. 2019 Mar 27;11(12):11125-11135. doi: 10.1021/acsami.8b18269. Epub 2019 Mar 12.

PMID:
30799601
2.

An exosomal- and interfacial-biosensing based strategy for remote monitoring of aberrantly phosphorylated proteins in lung cancer cells.

Ahmed M, Carrascosa LG, Wuethrich A, Mainwaring P, Trau M.

Biomater Sci. 2018 Aug 21;6(9):2336-2341. doi: 10.1039/c8bm00629f.

PMID:
30022183
4.

Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012).

Foffi G, Pastore A, Piazza F, Temussi PA.

Phys Biol. 2013 Aug;10(4):040301. Epub 2013 Aug 2.

PMID:
23912807
5.

Detection of aberrant protein phosphorylation in cancer using direct gold-protein affinity interactions.

Ahmed M, Carrascosa LG, Ibn Sina AA, Zarate EM, Korbie D, Ru KL, Shiddiky MJA, Mainwaring P, Trau M.

Biosens Bioelectron. 2017 May 15;91:8-14. doi: 10.1016/j.bios.2016.12.012. Epub 2016 Dec 7.

PMID:
27984707
6.

Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.

Lazzara MJ, Lane K, Chan R, Jasper PJ, Yaffe MB, Sorger PK, Jacks T, Neel BG, Lauffenburger DA.

Cancer Res. 2010 May 1;70(9):3843-50. doi: 10.1158/0008-5472.CAN-09-3421. Epub 2010 Apr 20.

7.

The interplay between protein stability and dynamics in conformational diseases: the case of hPGK1 deficiency.

Pey AL.

Biochim Biophys Acta. 2013 Dec;1834(12):2502-11. doi: 10.1016/j.bbapap.2013.07.011. Epub 2013 Aug 1.

PMID:
23911916
8.

Favourable native-like helical local interactions can accelerate protein folding.

Viguera AR, Villegas V, Avilés FX, Serrano L.

Fold Des. 1997;2(1):23-33.

9.

Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.

Tang Z, Jiang S, Du R, Petri ET, El-Telbany A, Chan PS, Kijima T, Dietrich S, Matsui K, Kobayashi M, Sasada S, Okamoto N, Suzuki H, Kawahara K, Iwasaki T, Nakagawa K, Kawase I, Christensen JG, Hirashima T, Halmos B, Salgia R, Boggon TJ, Kern JA, Ma PC.

Oncogene. 2009 Jan 29;28(4):518-33. doi: 10.1038/onc.2008.411. Epub 2008 Nov 17.

10.

Aptamers as a sensitive tool to detect subtle modifications in therapeutic proteins.

Zichel R, Chearwae W, Pandey GS, Golding B, Sauna ZE.

PLoS One. 2012;7(2):e31948. doi: 10.1371/journal.pone.0031948. Epub 2012 Feb 27.

11.

Using Cooperatively Folded Peptides To Measure Interaction Energies and Conformational Propensities.

Ardejani MS, Powers ET, Kelly JW.

Acc Chem Res. 2017 Aug 15;50(8):1875-1882. doi: 10.1021/acs.accounts.7b00195. Epub 2017 Jul 19.

12.
13.

Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

Tong J, Taylor P, Peterman SM, Prakash A, Moran MF.

Mol Cell Proteomics. 2009 Sep;8(9):2131-44. doi: 10.1074/mcp.M900148-MCP200. Epub 2009 Jun 15.

14.

Effect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM.

Coban O, Zanetti-Dominguez LC, Matthews DR, Rolfe DJ, Weitsman G, Barber PR, Barbeau J, Devauges V, Kampmeier F, Winn M, Vojnovic B, Parker PJ, Lidke KA, Lidke DS, Ameer-Beg SM, Martin-Fernandez ML, Ng T.

Biophys J. 2015 Mar 10;108(5):1013-26. doi: 10.1016/j.bpj.2015.01.005.

15.

Effects of the difference in the unfolded-state ensemble on the folding of Escherichia coli dihydrofolate reductase.

Arai M, Kataoka M, Kuwajima K, Matthews CR, Iwakura M.

J Mol Biol. 2003 Jun 13;329(4):779-91.

PMID:
12787677
16.

Conformational and Colloidal Stabilities of Isolated Constant Domains of Human Immunoglobulin G and Their Impact on Antibody Aggregation under Acidic Conditions.

Yageta S, Lauer TM, Trout BL, Honda S.

Mol Pharm. 2015 May 4;12(5):1443-55. doi: 10.1021/mp500759p. Epub 2015 Apr 23.

PMID:
25871775
17.
18.

Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers.

Wuethrich A, Sina AA, Ahmed M, Lin TY, Carrascosa LG, Trau M.

Nanoscale. 2018 Jun 14;10(23):10884-10890. doi: 10.1039/C7NR09496E.

PMID:
29565425

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