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Items: 1 to 20 of 101

1.

Novel hybrids of podophyllotoxin and formononetin inhibit the growth, migration and invasion of lung cancer cells.

Yang C, Xie Q, Zeng X, Tao N, Xu Y, Chen Y, Wang J, Zhang L.

Bioorg Chem. 2019 Apr;85:445-454. doi: 10.1016/j.bioorg.2019.02.019. Epub 2019 Feb 6.

PMID:
30776555
2.

Synthesis and Investigation of the Role of Benzopyran Dihydropyrimidinone Hybrids in Cell Proliferation, Migration and Tumor Growth.

Dash AK, Nayak D, Hussain N, Mintoo MJ, Bano S, Katoch A, Mondhe DM, Goswami A, Mukherjee D.

Anticancer Agents Med Chem. 2018 Sep 2. doi: 10.2174/1871520618666180903101422. [Epub ahead of print]

PMID:
30179143
3.

Novel Podophyllotoxin Derivatives as Potential Tubulin Inhibitors: Design, Synthesis, and Antiproliferative Activity Evaluation.

Han HW, Lin HY, He DL, Ren Y, Sun WX, Liang L, Du MH, Li DC, Chu YC, Yang MK, Wang XM, Yang YH.

Chem Biodivers. 2018 Nov;15(11):e1800289. doi: 10.1002/cbdv.201800289. Epub 2018 Oct 31.

PMID:
30194898
4.

Synthesis and anticancer activity of dimeric podophyllotoxin derivatives.

Zi CT, Yang L, Xu FQ, Dong FW, Yang D, Li Y, Ding ZT, Zhou J, Jiang ZH, Hu JM.

Drug Des Devel Ther. 2018 Oct 9;12:3393-3406. doi: 10.2147/DDDT.S167382. eCollection 2018.

5.

Design, synthesis and antineoplastic activity of novel hybrids of podophyllotoxin and indirubin against human leukaemia cancer cells as multifunctional anti-MDR agents.

Wang J, Long L, Chen Y, Xu Y, Zhang L.

Bioorg Med Chem Lett. 2018 Jun 1;28(10):1817-1824. doi: 10.1016/j.bmcl.2018.04.019. Epub 2018 Apr 10.

PMID:
29678463
6.

Synthesis and biological evaluation of podophyllotoxin derivatives as selective antitumor agents.

Wu GR, Xu B, Yang YQ, Zhang XY, Fang K, Ma T, Wang H, Xue NN, Chen M, Guo WB, Jia XH, Wang PL, Lei HM.

Eur J Med Chem. 2018 Jul 15;155:183-196. doi: 10.1016/j.ejmech.2018.05.052. Epub 2018 Jun 1.

PMID:
29886322
8.

Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines.

Kilic-Kurt Z, Bakar-Ates F, Karakas B, Kütük Ö.

Anticancer Agents Med Chem. 2018;18(9):1303-1312. doi: 10.2174/1871520618666180605082026.

PMID:
29866023
9.

Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.

Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.

Bioorg Med Chem. 2014 Oct 1;22(19):5466-75. doi: 10.1016/j.bmc.2014.07.031. Epub 2014 Jul 27.

PMID:
25131956
10.

Investigation of the mechanism and apoptotic pathway induced by 4β cinnamido linked podophyllotoxins against human lung cancer cells A549.

Kamal A, Nayak VL, Bagul C, Vishnuvardhan MV, Mallareddy A.

Apoptosis. 2015 Nov;20(11):1518-29. doi: 10.1007/s10495-015-1173-6.

PMID:
26386574
11.

Synthesis and cytotoxicity evaluation of novel podophyllotoxin derivatives.

Chengniu W, Zhonghua W, Yu Z, Chunyan N, Xiaodong Z, Li Z.

Arch Pharm (Weinheim). 2011 Nov;344(11):735-40. doi: 10.1002/ardp.201100095. Epub 2011 Sep 2.

PMID:
21887802
12.

4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.

Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.

Eur J Med Chem. 2018 Jan 20;144:595-611. doi: 10.1016/j.ejmech.2017.12.050. Epub 2017 Dec 14.

PMID:
29289884
13.

Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.

Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.

Bioorg Med Chem. 2014 May 1;22(9):2714-23. doi: 10.1016/j.bmc.2014.03.021. Epub 2014 Mar 22.

PMID:
24721832
14.

Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.

Ma Y, Fang S, Li H, Han C, Lu Y, Zhao Y, Liu Y, Zhao C.

Chem Biol Drug Des. 2013 Jul;82(1):12-21. doi: 10.1111/cbdd.12130.

PMID:
23786349
15.
16.

Antitumor evaluation of novel phenothiazine derivatives that inhibit migration and tubulin polymerization against gastric cancer MGC-803 cells.

Liu N, Jin Z, Zhang J, Jin J.

Invest New Drugs. 2019 Feb;37(1):188-198. doi: 10.1007/s10637-018-0682-x. Epub 2018 Oct 22.

PMID:
30345465
17.

Γ-Ionizing radiation-induced activation of the EGFR-p38/ERK-STAT3/CREB-1-EMT pathway promotes the migration/invasion of non-small cell lung cancer cells and is inhibited by podophyllotoxin acetate.

Cho JH, Hong WG, Jung YJ, Lee J, Lee E, Hwang SG, Um HD, Park JK.

Tumour Biol. 2016 Jun;37(6):7315-25. doi: 10.1007/s13277-015-4548-y. Epub 2015 Dec 15.

PMID:
26671552
18.

Synthesis of arylpyrazole linked benzimidazole conjugates as potential microtubule disruptors.

Kamal A, Shaik AB, Polepalli S, Kumar GB, Reddy VS, Mahesh R, Garimella S, Jain N.

Bioorg Med Chem. 2015 Mar 1;23(5):1082-95. doi: 10.1016/j.bmc.2015.01.004. Epub 2015 Jan 8.

PMID:
25648686
19.

Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.

Wang ZZ, Sun WX, Wang X, Zhang YH, Qiu HY, Qi JL, Pang YJ, Lu GH, Wang XM, Yu FG, Yang YH.

Chem Biol Drug Des. 2017 Aug;90(2):236-243. doi: 10.1111/cbdd.12942. Epub 2017 Feb 28.

PMID:
28079286
20.

Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties.

Shareef MA, Duscharla D, Ramasatyaveni G, Dhoke NR, Das A, Ummanni R, Srivastava AK.

Eur J Med Chem. 2015 Jan 7;89:128-37. doi: 10.1016/j.ejmech.2014.10.050. Epub 2014 Oct 18.

PMID:
25462233

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