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Items: 1 to 20 of 98

1.

PKNOX2 suppresses gastric cancer through the transcriptional activation of IGFBP5 and p53.

Zhang L, Li W, Cao L, Xu J, Qian Y, Chen H, Zhang Y, Kang W, Gou H, Wong CC, Yu J.

Oncogene. 2019 Feb 11. doi: 10.1038/s41388-019-0743-4. [Epub ahead of print]

PMID:
30745575
2.

Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.

Li X, Cheung KF, Ma X, Tian L, Zhao J, Go MY, Shen B, Cheng AS, Ying J, Tao Q, Sung JJ, Kung HF, Yu J.

Oncogene. 2012 Jul 19;31(29):3419-30. doi: 10.1038/onc.2011.511. Epub 2011 Nov 21. Erratum in: Oncogene. 2012 Jul 19;31(29):3482.

PMID:
22105368
3.

Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer.

Otani K, Dong Y, Li X, Lu J, Zhang N, Xu L, Go MY, Ng EK, Arakawa T, Chan FK, Sung JJ, Yu J.

J Pathol. 2014 Nov;234(3):302-15. doi: 10.1002/path.4391. Epub 2014 Aug 28.

4.

ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer.

Du W, Wang S, Zhou Q, Li X, Chu J, Chang Z, Tao Q, Ng EK, Fang J, Sung JJ, Yu J.

Oncogene. 2013 Jul 11;32(28):3319-28. doi: 10.1038/onc.2012.359. Epub 2012 Aug 20.

PMID:
22907434
5.

Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells.

Wang J, Ding N, Li Y, Cheng H, Wang D, Yang Q, Deng Y, Yang Y, Li Y, Ruan X, Xie F, Zhao H, Fang X.

Oncotarget. 2015 Aug 21;6(24):20636-49.

6.

Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis.

Wang L, Chen S, Xue M, Zhong J, Wang X, Gan L, Lam EK, Liu X, Zhang J, Zhou T, Yu J, Jin H, Si J.

Mol Med. 2012 May 9;18:389-400. doi: 10.2119/molmed.2011.00172.

7.

KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer.

Pei L, He X, Li S, Sun R, Xiang Q, Ren G, Xiang T.

Int J Oncol. 2018 Sep;53(3):961-972. doi: 10.3892/ijo.2018.4446. Epub 2018 Jun 19.

8.

Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway.

Li X, Liang Q, Liu W, Zhang N, Xu L, Zhang X, Zhang J, Sung JJ, Yu J.

Oncogene. 2016 May 12;35(19):2453-64. doi: 10.1038/onc.2015.300. Epub 2015 Aug 17.

PMID:
26279301
9.

LncRNA SNHG6 is Associated with Poor Prognosis of Gastric Cancer and Promotes Cell Proliferation and EMT through Epigenetically Silencing p27 and Sponging miR-101-3p.

Yan K, Tian J, Shi W, Xia H, Zhu Y.

Cell Physiol Biochem. 2017;42(3):999-1012. doi: 10.1159/000478682. Epub 2017 Jun 27.

10.

Paired box gene 5 is a novel tumor suppressor in hepatocellular carcinoma through interaction with p53 signaling pathway.

Liu W, Li X, Chu ES, Go MY, Xu L, Zhao G, Li L, Dai N, Si J, Tao Q, Sung JJ, Yu J.

Hepatology. 2011 Mar;53(3):843-53. doi: 10.1002/hep.24124. Epub 2011 Feb 11.

PMID:
21319196
11.

Downregulated PITX1 Modulated by MiR-19a-3p Promotes Cell Malignancy and Predicts a Poor Prognosis of Gastric Cancer by Affecting Transcriptionally Activated PDCD5.

Qiao F, Gong P, Song Y, Shen X, Su X, Li Y, Wu H, Zhao Z, Fan H.

Cell Physiol Biochem. 2018;46(6):2215-2231. doi: 10.1159/000489590. Epub 2018 May 3.

12.

Insulin-like growth factor binding protein 5 suppresses tumor growth and metastasis of human osteosarcoma.

Su Y, Wagner ER, Luo Q, Huang J, Chen L, He BC, Zuo GW, Shi Q, Zhang BQ, Zhu G, Bi Y, Luo J, Luo X, Kim SH, Shen J, Rastegar F, Huang E, Gao Y, Gao JL, Yang K, Wietholt C, Li M, Qin J, Haydon RC, He TC, Luu HH.

Oncogene. 2011 Sep 15;30(37):3907-17. doi: 10.1038/onc.2011.97. Epub 2011 Apr 4.

PMID:
21460855
13.

REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype.

Yu J, Liang Q, Wang J, Wang K, Gao J, Zhang J, Zeng Y, Chiu PW, Ng EK, Sung JJ.

Oncogene. 2017 Jan 12;36(2):182-193. doi: 10.1038/onc.2016.187. Epub 2016 May 23.

14.

Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival.

Xu L, Li X, Chu ES, Zhao G, Go MY, Tao Q, Jin H, Zeng Z, Sung JJ, Yu J.

Gut. 2012 Jul;61(7):977-85. doi: 10.1136/gutjnl-2011-300411. Epub 2011 Sep 13.

PMID:
21917650
15.

SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer.

Han F, Liu W, Jiang X, Shi X, Yin L, Ao L, Cui Z, Li Y, Huang C, Cao J, Liu J.

Oncogene. 2015 Aug 13;34(33):4391-402. doi: 10.1038/onc.2014.370. Epub 2014 Dec 1.

16.

The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5).

Müller M, Persson AB, Krueger K, Kirschner KM, Scholz H.

Gene. 2017 Jul 1;619:21-29. doi: 10.1016/j.gene.2017.03.037. Epub 2017 Mar 30.

PMID:
28366834
17.

Dapper homolog 1 is a novel tumor suppressor in gastric cancer through inhibiting the nuclear factor-κB signaling pathway.

Wang S, Kang W, Go MY, Tong JH, Li L, Zhang N, Tao Q, Li X, To KF, Sung JJ, Yu J.

Mol Med. 2012 Dec 20;18:1402-11. doi: 10.2119/molmed.2012.00243.

18.

MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome.

Wang K, Liang Q, Li X, Tsoi H, Zhang J, Wang H, Go MY, Chiu PW, Ng EK, Sung JJ, Yu J.

Gut. 2016 Oct;65(10):1619-31. doi: 10.1136/gutjnl-2015-309276. Epub 2015 Jul 23.

19.

Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer.

Liu WB, Han F, Du XH, Jiang X, Li YH, Liu Y, Chen HQ, Ao L, Cui ZH, Cao J, Liu JY.

Int J Cancer. 2014 Mar 15;134(6):1311-22. doi: 10.1002/ijc.28472. Epub 2013 Nov 11.

20.

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