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Items: 1 to 20 of 101

1.

Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.

Petrovic J, Zhou Y, Fasolino M, Goldman N, Schwartz GW, Mumbach MR, Nguyen SC, Rome KS, Sela Y, Zapataro Z, Blacklow SC, Kruhlak MJ, Shi J, Aster JC, Joyce EF, Little SC, Vahedi G, Pear WS, Faryabi RB.

Mol Cell. 2019 Mar 21;73(6):1174-1190.e12. doi: 10.1016/j.molcel.2019.01.006. Epub 2019 Feb 7.

PMID:
30745086
2.

A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.

Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS.

Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066.

3.

NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.

Clementz AG, Rogowski A, Pandya K, Miele L, Osipo C.

Breast Cancer Res. 2011 Jun 14;13(3):R63. doi: 10.1186/bcr2900.

4.

Enhancer diversity and the control of a simple pattern of Drosophila CNS midline cell expression.

Pearson JC, Crews ST.

Dev Biol. 2014 Aug 15;392(2):466-82. doi: 10.1016/j.ydbio.2014.05.011. Epub 2014 May 20.

5.

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.

Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):E4946-53. doi: 10.1073/pnas.1407079111. Epub 2014 Nov 4.

6.

Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions.

Nurick I, Shamir R, Elkon R.

Epigenetics Chromatin. 2018 Aug 29;11(1):49. doi: 10.1186/s13072-018-0220-2.

7.

Genome organization and long-range regulation of gene expression by enhancers.

Smallwood A, Ren B.

Curr Opin Cell Biol. 2013 Jun;25(3):387-94. doi: 10.1016/j.ceb.2013.02.005. Epub 2013 Mar 4. Review.

8.

Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition.

Novo CL, Javierre BM, Cairns J, Segonds-Pichon A, Wingett SW, Freire-Pritchett P, Furlan-Magaril M, Schoenfelder S, Fraser P, Rugg-Gunn PJ.

Cell Rep. 2018 Mar 6;22(10):2615-2627. doi: 10.1016/j.celrep.2018.02.040.

9.

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.

Wang H, Zang C, Taing L, Arnett KL, Wong YJ, Pear WS, Blacklow SC, Liu XS, Aster JC.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):705-10. doi: 10.1073/pnas.1315023111. Epub 2013 Dec 27.

10.

Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity.

Lubecka K, Kurzava L, Flower K, Buvala H, Zhang H, Teegarden D, Camarillo I, Suderman M, Kuang S, Andrisani O, Flanagan JM, Stefanska B.

Carcinogenesis. 2016 Jul;37(7):656-68. doi: 10.1093/carcin/bgw048. Epub 2016 Apr 28.

11.

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.

Ryan RJ, Drier Y, Whitton H, Cotton MJ, Kaur J, Issner R, Gillespie S, Epstein CB, Nardi V, Sohani AR, Hochberg EP, Bernstein BE.

Cancer Discov. 2015 Oct;5(10):1058-71. doi: 10.1158/2159-8290.CD-15-0370. Epub 2015 Jul 30.

12.

Chromatin boundary elements organize genomic architecture and developmental gene regulation in Drosophila Hox clusters.

Ma Z, Li M, Roy S, Liu KJ, Romine ML, Lane DC, Patel SK, Cai HN.

World J Biol Chem. 2016 Aug 26;7(3):223-30. doi: 10.4331/wjbc.v7.i3.223. Review.

13.

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.

Sabò A, Kress TR, Pelizzola M, de Pretis S, Gorski MM, Tesi A, Morelli MJ, Bora P, Doni M, Verrecchia A, Tonelli C, Fagà G, Bianchi V, Ronchi A, Low D, Müller H, Guccione E, Campaner S, Amati B.

Nature. 2014 Jul 24;511(7510):488-492. doi: 10.1038/nature13537. Epub 2014 Jul 9.

14.

Emerging roles of transcriptional enhancers in chromatin looping and promoter-proximal pausing of RNA polymerase II.

Meng H, Bartholomew B.

J Biol Chem. 2018 Sep 7;293(36):13786-13794. doi: 10.1074/jbc.R117.813485. Epub 2017 Nov 29. Review.

PMID:
29187597
15.

The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.

Geimer Le Lay AS, Oravecz A, Mastio J, Jung C, Marchal P, Ebel C, Dembélé D, Jost B, Le Gras S, Thibault C, Borggrefe T, Kastner P, Chan S.

Sci Signal. 2014 Mar 18;7(317):ra28. doi: 10.1126/scisignal.2004545.

PMID:
24643801
16.

Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations.

Zhang Y, Wong CH, Birnbaum RY, Li G, Favaro R, Ngan CY, Lim J, Tai E, Poh HM, Wong E, Mulawadi FH, Sung WK, Nicolis S, Ahituv N, Ruan Y, Wei CL.

Nature. 2013 Dec 12;504(7479):306-310. doi: 10.1038/nature12716. Epub 2013 Nov 10.

17.

Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression.

Quigley IK, Kintner C.

PLoS Genet. 2017 Jan 19;13(1):e1006538. doi: 10.1371/journal.pgen.1006538. eCollection 2017 Jan.

18.

Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization.

Chepelev I, Wei G, Wangsa D, Tang Q, Zhao K.

Cell Res. 2012 Mar;22(3):490-503. doi: 10.1038/cr.2012.15. Epub 2012 Jan 24.

19.

A DNA transcription code for cell-specific gene activation by notch signaling.

Cave JW, Loh F, Surpris JW, Xia L, Caudy MA.

Curr Biol. 2005 Jan 26;15(2):94-104.

20.

Chromatin looping and organization at developmentally regulated gene loci.

Noordermeer D, Duboule D.

Wiley Interdiscip Rev Dev Biol. 2013 Sep-Oct;2(5):615-30. doi: 10.1002/wdev.103. Epub 2013 Jan 3. Review.

PMID:
24014450

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