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Items: 1 to 20 of 97

1.

Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis.

Torres-Hernandez A, Wang W, Nikiforov Y, Tejada K, Torres L, Kalabin A, Wu Y, Haq MIU, Khan MY, Zhao Z, Su W, Camargo J, Hundeyin M, Diskin B, Adam S, Rossi JAK, Kurz E, Aykut B, Shadaloey SAA, Leinwand J, Miller G.

Oncogene. 2019 Feb 11. doi: 10.1038/s41388-019-0734-5. [Epub ahead of print]

PMID:
30742098
2.

B lymphocytes limit senescence-driven fibrosis resolution and favor hepatocarcinogenesis in mouse liver injury.

Faggioli F, Palagano E, Di Tommaso L, Donadon M, Marrella V, Recordati C, Mantero S, Villa A, Vezzoni P, Cassani B.

Hepatology. 2018 May;67(5):1970-1985. doi: 10.1002/hep.29636. Epub 2018 Mar 25.

PMID:
29105104
3.

Cooperation of liver cells in health and disease.

Kmieć Z.

Adv Anat Embryol Cell Biol. 2001;161:III-XIII, 1-151. Review.

PMID:
11729749
4.

Tyrosine kinase SYK is a potential therapeutic target for liver fibrosis.

Qu C, Zheng D, Li S, Liu Y, Lidofsky A, Holmes JA, Chen J, He L, Wei L, Liao Y, Yuan H, Jin Q, Lin Z, Hu Q, Jiang Y, Tu M, Chen X, Li W, Lin W, Fuchs BC, Chung RT, Hong J.

Hepatology. 2018 Mar 14. doi: 10.1002/hep.29881. [Epub ahead of print]

PMID:
29537660
5.

Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model.

Chung SI, Moon H, Ju HL, Cho KJ, Kim DY, Han KH, Eun JW, Nam SW, Ribback S, Dombrowski F, Calvisi DF, Ro SW.

J Hepatol. 2016 Mar;64(3):618-27. doi: 10.1016/j.jhep.2015.10.007. Epub 2015 Oct 22.

PMID:
26471504
6.

Therapeutic effects of serum extracellular vesicles in liver fibrosis.

Chen L, Chen R, Kemper S, Cong M, You H, Brigstock DR.

J Extracell Vesicles. 2018 Apr 17;7(1):1461505. doi: 10.1080/20013078.2018.1461505. eCollection 2018.

7.

Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice.

Kong X, Feng D, Wang H, Hong F, Bertola A, Wang FS, Gao B.

Hepatology. 2012 Sep;56(3):1150-9. doi: 10.1002/hep.25744. Epub 2012 Jul 12.

8.

Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/mTOR/p70S6K and TGFβ/Smad signalling pathways.

Li J, Li X, Xu W, Wang S, Hu Z, Zhang Q, Deng X, Wang J, Zhang J, Guo C.

Liver Int. 2015 Apr;35(4):1222-33. doi: 10.1111/liv.12638. Epub 2014 Aug 5.

PMID:
25040634
9.

Dectin-1 Regulates Hepatic Fibrosis and Hepatocarcinogenesis by Suppressing TLR4 Signaling Pathways.

Seifert L, Deutsch M, Alothman S, Alqunaibit D, Werba G, Pansari M, Pergamo M, Ochi A, Torres-Hernandez A, Levie E, Tippens D, Greco SH, Tiwari S, Ly NNG, Eisenthal A, van Heerden E, Avanzi A, Barilla R, Zambirinis CP, Rendon M, Daley D, Pachter HL, Hajdu C, Miller G.

Cell Rep. 2015 Dec 1;13(9):1909-1921. doi: 10.1016/j.celrep.2015.10.058. Epub 2015 Nov 19.

10.

Inhibition of spleen tyrosine kinase (syk) suppresses renal fibrosis through anti-inflammatory effects and down regulation of the MAPK-p38 pathway.

Chen KH, Hsu HH, Yang HY, Tian YC, Ko YC, Yang CW, Hung CC.

Int J Biochem Cell Biol. 2016 May;74:135-44. doi: 10.1016/j.biocel.2016.03.001. Epub 2016 Mar 3.

PMID:
26948651
11.

Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence.

Jin H, Lian N, Zhang F, Chen L, Chen Q, Lu C, Bian M, Shao J, Wu L, Zheng S.

Cell Death Dis. 2016 Apr 14;7:e2189. doi: 10.1038/cddis.2016.92.

12.

The innate immune receptor TREM-1 promotes liver injury and fibrosis.

Nguyen-Lefebvre AT, Ajith A, Portik-Dobos V, Horuzsko DD, Arbab AS, Dzutsev A, Sadek R, Trinchieri G, Horuzsko A.

J Clin Invest. 2018 Nov 1;128(11):4870-4883. doi: 10.1172/JCI98156. Epub 2018 Oct 2.

13.

Interleukin-15 receptor α on hepatic stellate cells regulates hepatic fibrogenesis in mice.

Jiao J, Ooka K, Fey H, Fiel MI, Rahmman AH, Kojima K, Hoshida Y, Chen X, de Paula T, Vetter D, Sastre D, Lee KH, Lee Y, Bansal M, Friedman SL, Merad M, Aloman C.

J Hepatol. 2016 Aug;65(2):344-353. doi: 10.1016/j.jhep.2016.04.020. Epub 2016 May 3.

14.

IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation.

Tan Z, Qian X, Jiang R, Liu Q, Wang Y, Chen C, Wang X, Ryffel B, Sun B.

J Immunol. 2013 Aug 15;191(4):1835-44. doi: 10.4049/jimmunol.1203013. Epub 2013 Jul 10.

15.

Apoptosis of hepatic stellate cells mediated by specific protein nitration.

Mòdol T, Natal C, Pérez de Obanos MP, Domingo de Miguel E, Iraburu MJ, López-Zabalza MJ.

Biochem Pharmacol. 2011 Feb 1;81(3):451-8. doi: 10.1016/j.bcp.2010.10.017. Epub 2010 Nov 4.

PMID:
21056031
16.

Dihydroartemisinin counteracts fibrotic portal hypertension via farnesoid X receptor-dependent inhibition of hepatic stellate cell contraction.

Xu W, Lu C, Zhang F, Shao J, Yao S, Zheng S.

FEBS J. 2017 Jan;284(1):114-133. doi: 10.1111/febs.13956. Epub 2016 Nov 29.

17.

Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice.

Meng F, Wang K, Aoyama T, Grivennikov SI, Paik Y, Scholten D, Cong M, Iwaisako K, Liu X, Zhang M, Österreicher CH, Stickel F, Ley K, Brenner DA, Kisseleva T.

Gastroenterology. 2012 Sep;143(3):765-776.e3. doi: 10.1053/j.gastro.2012.05.049. Epub 2012 Jun 8.

18.

Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes.

Wang ME, Chen YC, Chen IS, Hsieh SC, Chen SS, Chiu CH.

J Nutr Biochem. 2012 Oct;23(10):1352-66. doi: 10.1016/j.jnutbio.2011.08.004. Epub 2012 Jan 4.

PMID:
22221674
19.

Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells.

Chong LW, Hsu YC, Lee TF, Lin Y, Chiu YT, Yang KC, Wu JC, Huang YT.

BMC Gastroenterol. 2015 Feb 15;15:22. doi: 10.1186/s12876-015-0248-8.

20.

NLRC5 regulates TGF-β1-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis.

Xu T, Ni MM, Xing-Li, Li XF, Meng XM, Huang C, Li J.

Int J Biochem Cell Biol. 2016 Jan;70:92-104. doi: 10.1016/j.biocel.2015.11.010. Epub 2015 Nov 26.

PMID:
26592197

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