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Items: 1 to 20 of 103

1.

S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes.

Cheng P, Eksioglu EA, Chen X, Kandell W, Le Trinh T, Cen L, Qi J, Sallman DA, Zhang Y, Tu N, Adams WA, Zhang C, Liu J, Cleveland JL, List AF, Wei S.

Leukemia. 2019 Feb 8. doi: 10.1038/s41375-019-0397-9. [Epub ahead of print]

PMID:
30737486
2.

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

Wei Y, Zheng H, Bao N, Jiang S, Bueso-Ramos CE, Khoury J, Class C, Lu Y, Lin K, Yang H, Ganan-Gomez I, Starczynowski DT, Do KA, Colla S, Garcia-Manero G.

Blood Adv. 2018 Oct 9;2(19):2491-2504. doi: 10.1182/bloodadvances.2018024166.

3.

Progress in Myelodysplastic Syndromes: Clinicopathologic Correlations and Immune Checkpoints.

Hidalgo-López JE, Kanagal-Shamanna R, Quesada AE, Thakral B, Hu Z, Mitsuhashi T, Yabe M, Garcia-Manero G, Bueso-Ramos CE.

Clin Lymphoma Myeloma Leuk. 2017 Jul;17S:S16-S25. doi: 10.1016/j.clml.2017.02.022.

PMID:
28760297
4.

Bone marrow niche in the myelodysplastic syndromes.

Cogle CR, Saki N, Khodadi E, Li J, Shahjahani M, Azizidoost S.

Leuk Res. 2015 Oct;39(10):1020-7. doi: 10.1016/j.leukres.2015.06.017. Epub 2015 Jul 14. Review.

PMID:
26276090
5.

Novel therapeutic approach to improve hematopoiesis in low risk MDS by targeting MDSCs with the Fc-engineered CD33 antibody BI 836858.

Eksioglu EA, Chen X, Heider KH, Rueter B, McGraw KL, Basiorka AA, Wei M, Burnette A, Cheng P, Lancet J, Komrokji R, Djeu J, List A, Wei S.

Leukemia. 2017 Oct;31(10):2172-2180. doi: 10.1038/leu.2017.21. Epub 2017 Jan 18.

6.

Inappropriate Notch activity and limited mesenchymal stem cell plasticity in the bone marrow of patients with myelodysplastic syndromes.

Varga G, Kiss J, Várkonyi J, Vas V, Farkas P, Pálóczi K, Uher F.

Pathol Oncol Res. 2007;13(4):311-9. Epub 2007 Dec 25.

7.

Induction of myelodysplasia by myeloid-derived suppressor cells.

Chen X, Eksioglu EA, Zhou J, Zhang L, Djeu J, Fortenbery N, Epling-Burnette P, Van Bijnen S, Dolstra H, Cannon J, Youn JI, Donatelli SS, Qin D, De Witte T, Tao J, Wang H, Cheng P, Gabrilovich DI, List A, Wei S.

J Clin Invest. 2013 Nov;123(11):4595-611.

8.

Physician Education: Myelodysplastic Syndrome.

Yoshida Y.

Oncologist. 1996;1(4):284-287.

9.

Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling.

Varney ME, Niederkorn M, Konno H, Matsumura T, Gohda J, Yoshida N, Akiyama T, Christie S, Fang J, Miller D, Jerez A, Karsan A, Maciejewski JP, Meetei RA, Inoue J, Starczynowski DT.

J Exp Med. 2015 Oct 19;212(11):1967-85. doi: 10.1084/jem.20141898. Epub 2015 Oct 12.

10.

Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents.

Yang H, Bueso-Ramos C, DiNardo C, Estecio MR, Davanlou M, Geng QR, Fang Z, Nguyen M, Pierce S, Wei Y, Parmar S, Cortes J, Kantarjian H, Garcia-Manero G.

Leukemia. 2014 Jun;28(6):1280-8. doi: 10.1038/leu.2013.355. Epub 2013 Nov 25.

11.

Fas/Apo-1 (CD95) expression and apoptosis in patients with myelodysplastic syndromes.

Bouscary D, De Vos J, Guesnu M, Jondeau K, Viguier F, Melle J, Picard F, Dreyfus F, Fontenay-Roupie M.

Leukemia. 1997 Jun;11(6):839-45.

PMID:
9177438
12.

Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype.

Sallman DA, Cluzeau T, Basiorka AA, List A.

Front Oncol. 2016 Jun 16;6:151. doi: 10.3389/fonc.2016.00151. eCollection 2016. Review.

13.

Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.

Zhou L, Nguyen AN, Sohal D, Ying Ma J, Pahanish P, Gundabolu K, Hayman J, Chubak A, Mo Y, Bhagat TD, Das B, Kapoun AM, Navas TA, Parmar S, Kambhampati S, Pellagatti A, Braunchweig I, Zhang Y, Wickrema A, Medicherla S, Boultwood J, Platanias LC, Higgins LS, List AF, Bitzer M, Verma A.

Blood. 2008 Oct 15;112(8):3434-43. doi: 10.1182/blood-2008-02-139824. Epub 2008 May 12.

14.

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype.

Basiorka AA, McGraw KL, Eksioglu EA, Chen X, Johnson J, Zhang L, Zhang Q, Irvine BA, Cluzeau T, Sallman DA, Padron E, Komrokji R, Sokol L, Coll RC, Robertson AA, Cooper MA, Cleveland JL, O'Neill LA, Wei S, List AF.

Blood. 2016 Dec 22;128(25):2960-2975. doi: 10.1182/blood-2016-07-730556. Epub 2016 Oct 13.

15.

Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells.

Rajapaksa R, Ginzton N, Rott LS, Greenberg PL.

Blood. 1996 Dec 1;88(11):4275-87.

16.

Immune checkpoint regulator PD-L1 expression on tumor cells by contacting CD11b positive bone marrow derived stromal cells.

Noh H, Hu J, Wang X, Xia X, Satelli A, Li S.

Cell Commun Signal. 2015 Feb 27;13:14. doi: 10.1186/s12964-015-0093-y.

17.

Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?

Pleyer L, Valent P, Greil R.

Int J Mol Sci. 2016 Jun 27;17(7). pii: E1009. doi: 10.3390/ijms17071009. Review.

18.

Leukemia cells impair normal hematopoiesis and induce functionally loss of hematopoietic stem cells through immune cells and inflammation.

Cui P, Zhang Y, Cui M, Li Z, Ma G, Wang R, Wang N, Huang S, Gao J.

Leuk Res. 2018 Feb;65:49-54. doi: 10.1016/j.leukres.2018.01.002. Epub 2018 Jan 2.

PMID:
29306107
19.

Feedback signals in myelodysplastic syndromes: increased self-renewal of the malignant clone suppresses normal hematopoiesis.

Walenda T, Stiehl T, Braun H, Fröbel J, Ho AD, Schroeder T, Goecke TW, Rath B, Germing U, Marciniak-Czochra A, Wagner W.

PLoS Comput Biol. 2014 Apr 24;10(4):e1003599. doi: 10.1371/journal.pcbi.1003599. eCollection 2014 Apr.

20.

Effect of cA2 anti-tumor necrosis factor-alpha antibody therapy on hematopoiesis of patients with myelodysplastic syndromes.

Boula A, Voulgarelis M, Giannouli S, Katrinakis G, Psyllaki M, Pontikoglou C, Markidou F, Eliopoulos GD, Papadaki HA.

Clin Cancer Res. 2006 May 15;12(10):3099-108.

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