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Items: 1 to 20 of 93

1.

Alamandine attenuates arterial remodelling induced by transverse aortic constriction in mice.

de Souza-Neto FP, Silva MME, Santuchi MC, de Alcântara-Leonídio TC, Motta-Santos D, Oliveira AC, Melo MB, Canta GN, de Souza LE, Irigoyen MCC, Campagnole-Santos MJ, Guatimosim S, Santos RAS, da Silva RF.

Clin Sci (Lond). 2019 Mar 1;133(5):629-643. doi: 10.1042/CS20180547. Print 2019 Mar 15.

PMID:
30737255
2.

Aortic remodeling after transverse aortic constriction in mice is attenuated with AT1 receptor blockade.

Kuang SQ, Geng L, Prakash SK, Cao JM, Guo S, Villamizar C, Kwartler CS, Peters AM, Brasier AR, Milewicz DM.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2172-9. doi: 10.1161/ATVBAHA.113.301624. Epub 2013 Jul 18.

3.

Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.

Lautner RQ, Villela DC, Fraga-Silva RA, Silva N, Verano-Braga T, Costa-Fraga F, Jankowski J, Jankowski V, Sousa F, Alzamora A, Soares E, Barbosa C, Kjeldsen F, Oliveira A, Braga J, Savergnini S, Maia G, Peluso AB, Passos-Silva D, Ferreira A, Alves F, Martins A, Raizada M, Paula R, Motta-Santos D, Klempin F, Pimenta A, Alenina N, Sinisterra R, Bader M, Campagnole-Santos MJ, Santos RA.

Circ Res. 2013 Apr 12;112(8):1104-11. doi: 10.1161/CIRCRESAHA.113.301077. Epub 2013 Feb 27. Erratum in: Circ Res. 2013 May 24;112(11):e156. Kemplin, Friederike [corrected to Klempin, Friederike].

PMID:
23446738
4.

Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo.

de Carvalho Santuchi M, Dutra MF, Vago JP, Lima KM, Galvão I, de Souza-Neto FP, Morais E Silva M, Oliveira AC, de Oliveira FCB, Gonçalves R, Teixeira MM, Sousa LP, Dos Santos RAS, da Silva RF.

Mediators Inflamm. 2019 Feb 21;2019:2401081. doi: 10.1155/2019/2401081. eCollection 2019.

5.

Administration of antioxidant peptide SS-31 attenuates transverse aortic constriction-induced pulmonary arterial hypertension in mice.

Lu HI, Huang TH, Sung PH, Chen YL, Chua S, Chai HY, Chung SY, Liu CF, Sun CK, Chang HW, Zhen YY, Lee FY, Yip HK.

Acta Pharmacol Sin. 2016 May;37(5):589-603. doi: 10.1038/aps.2015.162. Epub 2016 Apr 11.

6.

Genetic deletion of the alamandine receptor MRGD leads to dilated cardiomyopathy in mice.

Oliveira AC, Melo MB, Motta-Santos D, Peluso AA, Souza-Neto F, da Silva RF, Almeida JFQ, Canta G, Reis AM, Goncalves G, Cerri G, Coutinho D, Guedes de Jesus IC, Guatimosim S, Linhares ND, Alenina N, Bader M, Campagnole-Santos MJ, Santos RAS.

Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H123-H133. doi: 10.1152/ajpheart.00075.2018. Epub 2018 Oct 19.

PMID:
30339496
7.

Effect of an acute mechanical stimulus on aortic structure in the transverse aortic constriction mouse model.

Chen J, Wu J, Li L, Zou YZ, Zhu DL, Gao PJ.

Clin Exp Pharmacol Physiol. 2011 Sep;38(9):570-6. doi: 10.1111/j.1440-1681.2011.05544.x.

PMID:
21615773
8.

Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms.

Qaradakhi T, Matsoukas MT, Hayes A, Rybalka E, Caprnda M, Rimarova K, Sepsi M, Büsselberg D, Kruzliak P, Matsoukas J, Apostolopoulos V, Zulli A.

Cardiovasc Ther. 2017 Dec;35(6). doi: 10.1111/1755-5922.12306. Epub 2017 Oct 4.

PMID:
28901725
9.

Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy.

Wang K, Lu D, Zhang B, Wang S, Liu Q, Zhang Q, Geng J, Shan Q.

Cell Physiol Biochem. 2016;40(3-4):465-476. Epub 2016 Nov 25.

10.

BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery.

Merino D, Villar AV, García R, Tramullas M, Ruiz L, Ribas C, Cabezudo S, Nistal JF, Hurlé MA.

Cardiovasc Res. 2016 Jun 1;110(3):331-45. doi: 10.1093/cvr/cvw076. Epub 2016 Apr 11.

PMID:
27068510
11.

Alamandine abrogates neutrophil degranulation in atherosclerotic mice.

Da Silva AR, Lenglet S, Carbone F, Burger F, Roth A, Liberale L, Bonaventura A, Dallegri F, Stergiopulos N, Santos RA, Mach F, Fraga-Silva RA, Montecucco F.

Eur J Clin Invest. 2017 Feb;47(2):117-128. doi: 10.1111/eci.12708. Epub 2017 Jan 4.

PMID:
27930810
12.

Alamandine: a new member of the angiotensin family.

Villela DC, Passos-Silva DG, Santos RA.

Curr Opin Nephrol Hypertens. 2014 Mar;23(2):130-4. doi: 10.1097/01.mnh.0000441052.44406.92. Review.

PMID:
24389733
13.

Ascending aortic adventitial remodeling and fibrosis are ameliorated with Apelin-13 in rats after TAC via suppression of the miRNA-122 and LGR4-β-catenin signaling.

Xu R, Zhang ZZ, Chen LJ, Yu HM, Guo SJ, Xu YL, Oudit GY, Zhang Y, Chang Q, Song B, Chen DR, Zhu DL, Zhong JC.

Peptides. 2016 Dec;86:85-94. doi: 10.1016/j.peptides.2016.10.005. Epub 2016 Oct 20.

PMID:
27773659
14.

Hypotensive effect induced by microinjection of Alamandine, a derivative of angiotensin-(1-7), into caudal ventrolateral medulla of 2K1C hypertensive rats.

Soares ER, Barbosa CM, Campagnole-Santos MJ, Santos RAS, Alzamora AC.

Peptides. 2017 Oct;96:67-75. doi: 10.1016/j.peptides.2017.09.005. Epub 2017 Sep 8.

PMID:
28889964
15.

Angiotensin A/Alamandine/MrgD Axis: Another Clue to Understanding Cardiovascular Pathophysiology.

Hrenak J, Paulis L, Simko F.

Int J Mol Sci. 2016 Jul 20;17(7). pii: E1098. doi: 10.3390/ijms17071098. Review.

16.

Cardiac hypertrophy is enhanced in PPAR alpha-/- mice in response to chronic pressure overload.

Smeets PJ, Teunissen BE, Willemsen PH, van Nieuwenhoven FA, Brouns AE, Janssen BJ, Cleutjens JP, Staels B, van der Vusse GJ, van Bilsen M.

Cardiovasc Res. 2008 Apr 1;78(1):79-89. doi: 10.1093/cvr/cvn001. Epub 2008 Jan 10.

PMID:
18187461
17.

Reversal of Aortic Enlargement Induced by Increased Biomechanical Forces Requires AT1R Inhibition in Conjunction With AT2R Activation.

Zhou Z, Peters AM, Wang S, Janda A, Chen J, Zhou P, Arthur E, Kwartler CS, Milewicz DM.

Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):459-466. doi: 10.1161/ATVBAHA.118.312158.

PMID:
30602301
18.

Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue.

Uchiyama T, Okajima F, Mogi C, Tobo A, Tomono S, Sato K.

PLoS One. 2017 Jun 7;12(6):e0178769. doi: 10.1371/journal.pone.0178769. eCollection 2017.

19.

Reduction of angiotensin A and alamandine vasoactivity in the rabbit model of atherogenesis: differential effects of alamandine and Ang(1-7).

Habiyakare B, Alsaadon H, Mathai ML, Hayes A, Zulli A.

Int J Exp Pathol. 2014 Aug;95(4):290-5. doi: 10.1111/iep.12087. Epub 2014 Jun 20.

20.

ACE inhibition, ACE2 and angiotensin-(1-7) axis in kidney and cardiac inflammation and fibrosis.

Simões E Silva AC, Teixeira MM.

Pharmacol Res. 2016 May;107:154-162. doi: 10.1016/j.phrs.2016.03.018. Epub 2016 Mar 17. Review.

PMID:
26995300

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