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Items: 1 to 20 of 105

1.

Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation.

Nakamura-Ishizu A, Matsumura T, Stumpf PS, Umemoto T, Takizawa H, Takihara Y, O'Neil A, Majeed ABBA, MacArthur BD, Suda T.

Cell Rep. 2018 Nov 13;25(7):1772-1785.e6. doi: 10.1016/j.celrep.2018.10.059.

2.

Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin.

Nakamura-Ishizu A, Takubo K, Fujioka M, Suda T.

Biochem Biophys Res Commun. 2014 Nov 14;454(2):353-7. Epub 2014 Oct 24.

PMID:
25451253
3.

CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow.

Nakamura-Ishizu A, Takubo K, Kobayashi H, Suzuki-Inoue K, Suda T.

J Exp Med. 2015 Nov 16;212(12):2133-46. doi: 10.1084/jem.20150057. Epub 2015 Nov 9. Erratum in: J Exp Med. 2015 Dec 14;212(13):2323.

4.

Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.

Kohlscheen S, Wintterle S, Schwarzer A, Kamp C, Brugman MH, Breuer DC, Büsche G, Baum C, Modlich U.

PLoS One. 2015 Jul 6;10(7):e0131866. doi: 10.1371/journal.pone.0131866. eCollection 2015.

5.

Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche.

Yoshihara H, Arai F, Hosokawa K, Hagiwara T, Takubo K, Nakamura Y, Gomei Y, Iwasaki H, Matsuoka S, Miyamoto K, Miyazaki H, Takahashi T, Suda T.

Cell Stem Cell. 2007 Dec 13;1(6):685-97. doi: 10.1016/j.stem.2007.10.020. Epub 2007 Nov 20.

6.

Niche regulation of hematopoietic stem cells in the endosteum.

Arai F, Yoshihara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Suda T.

Ann N Y Acad Sci. 2009 Sep;1176:36-46. doi: 10.1111/j.1749-6632.2009.04561.x.

PMID:
19796231
7.

Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells.

Qian H, Buza-Vidas N, Hyland CD, Jensen CT, Antonchuk J, Månsson R, Thoren LA, Ekblom M, Alexander WS, Jacobsen SE.

Cell Stem Cell. 2007 Dec 13;1(6):671-84. doi: 10.1016/j.stem.2007.10.008. Epub 2007 Nov 20.

8.

Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells.

Carrelha J, Meng Y, Kettyle LM, Luis TC, Norfo R, Alcolea V, Boukarabila H, Grasso F, Gambardella A, Grover A, Högstrand K, Lord AM, Sanjuan-Pla A, Woll PS, Nerlov C, Jacobsen SEW.

Nature. 2018 Feb 1;554(7690):106-111. doi: 10.1038/nature25455. Epub 2018 Jan 3.

PMID:
29298288
9.

A network map of thrombopoietin signaling.

Bhat FA, Advani J, Khan AA, Mohan S, Pal A, Gowda H, Chakrabarti P, Keshava Prasad TS, Chatterjee A.

J Cell Commun Signal. 2018 Dec;12(4):737-743. doi: 10.1007/s12079-018-0480-4. Epub 2018 Jul 24.

10.

GSK-3β negatively regulates megakaryocyte differentiation and platelet production from primary human bone marrow cells in vitro.

Ono M, Matsubara Y, Shibano T, Ikeda Y, Murata M.

Platelets. 2011;22(3):196-203. doi: 10.3109/09537104.2010.541959. Epub 2011 Jan 13.

PMID:
21231855
11.

Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.

Buza-Vidas N, Antonchuk J, Qian H, Månsson R, Luc S, Zandi S, Anderson K, Takaki S, Nygren JM, Jensen CT, Jacobsen SE.

Genes Dev. 2006 Aug 1;20(15):2018-23.

12.

TGFβ-Mediated Downregulation of Thrombopoietin Is Associated With Platelet Decline in Asymptomatic SIV Infection.

Metcalf Pate KA, Lyons CE, Dorsey JL, Queen SE, Adams RJ, Morrell CN, Mankowski JL.

J Acquir Immune Defic Syndr. 2014 Apr 15;65(5):510-6. doi: 10.1097/QAI.0000000000000048.

13.

Ex vivo expansion of megakaryocyte progenitors: effect of various growth factor combinations on CD34+ progenitor cells from bone marrow and G-CSF-mobilized peripheral blood.

Gehling UM, Ryder JW, Hogan CJ, Hami L, McNiece I, Franklin W, Williams S, Helm K, King J, Shpall EJ.

Exp Hematol. 1997 Oct;25(11):1125-39.

PMID:
9328449
14.

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

Sanjuan-Pla A, Macaulay IC, Jensen CT, Woll PS, Luis TC, Mead A, Moore S, Carella C, Matsuoka S, Bouriez Jones T, Chowdhury O, Stenson L, Lutteropp M, Green JC, Facchini R, Boukarabila H, Grover A, Gambardella A, Thongjuea S, Carrelha J, Tarrant P, Atkinson D, Clark SA, Nerlov C, Jacobsen SE.

Nature. 2013 Oct 10;502(7470):232-6. doi: 10.1038/nature12495. Epub 2013 Aug 11.

PMID:
23934107
15.

Novel hematopoietic progenitor populations revealed by direct assessment of GATA1 protein expression and cMPL signaling events.

Heffner GC, Clutter MR, Nolan GP, Weissman IL.

Stem Cells. 2011 Nov;29(11):1774-82. doi: 10.1002/stem.719.

16.

Hierarchical structure of human megakaryocyte progenitor cells.

Hoffman R, Murrav LJ, Young JC, Luens KM, Bruno E.

Stem Cells. 1996;14 Suppl 1:75-81. Review.

17.

Mitochondrial Role in Stemness and Differentiation of Hematopoietic Stem Cells.

Papa L, Djedaini M, Hoffman R.

Stem Cells Int. 2019 Feb 6;2019:4067162. doi: 10.1155/2019/4067162. eCollection 2019. Review.

18.

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.

Avecilla ST, Hattori K, Heissig B, Tejada R, Liao F, Shido K, Jin DK, Dias S, Zhang F, Hartman TE, Hackett NR, Crystal RG, Witte L, Hicklin DJ, Bohlen P, Eaton D, Lyden D, de Sauvage F, Rafii S.

Nat Med. 2004 Jan;10(1):64-71. Epub 2003 Dec 21.

PMID:
14702636
19.

Mitophagy in hematopoietic stem cells: the case for exploration.

Joshi A, Kundu M.

Autophagy. 2013 Nov 1;9(11):1737-49. doi: 10.4161/auto.26681. Epub 2013 Oct 11. Review.

20.

Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia.

Heckl D, Wicke DC, Brugman MH, Meyer J, Schambach A, Büsche G, Ballmaier M, Baum C, Modlich U.

Blood. 2011 Apr 7;117(14):3737-47. doi: 10.1182/blood-2010-09-308262. Epub 2011 Feb 2.

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