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Items: 1 to 20 of 101

1.

Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.

Ryu JK, Rafalski VA, Meyer-Franke A, Adams RA, Poda SB, Rios Coronado PE, Pedersen LØ, Menon V, Baeten KM, Sikorski SL, Bedard C, Hanspers K, Bardehle S, Mendiola AS, Davalos D, Machado MR, Chan JP, Plastira I, Petersen MA, Pfaff SJ, Ang KK, Hallenbeck KK, Syme C, Hakozaki H, Ellisman MH, Swanson RA, Zamvil SS, Arkin MR, Zorn SH, Pico AR, Mucke L, Freedman SB, Stavenhagen JB, Nelson RB, Akassoglou K.

Nat Immunol. 2018 Nov;19(11):1212-1223. doi: 10.1038/s41590-018-0232-x. Epub 2018 Oct 15.

2.

Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.

Qin H, Buckley JA, Li X, Liu Y, Fox TH 3rd, Meares GP, Yu H, Yan Z, Harms AS, Li Y, Standaert DG, Benveniste EN.

J Neurosci. 2016 May 4;36(18):5144-59. doi: 10.1523/JNEUROSCI.4658-15.2016.

3.

Fibrinogen and altered hemostasis in Alzheimer's disease.

Cortes-Canteli M, Zamolodchikov D, Ahn HJ, Strickland S, Norris EH.

J Alzheimers Dis. 2012;32(3):599-608. doi: 10.3233/JAD-2012-120820. Review.

4.

The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease.

Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, Akassoglou K.

J Exp Med. 2007 Mar 19;204(3):571-82. Epub 2007 Mar 5.

5.

Targeting innate immunity for neurodegenerative disorders of the central nervous system.

Andreasson KI, Bachstetter AD, Colonna M, Ginhoux F, Holmes C, Lamb B, Landreth G, Lee DC, Low D, Lynch MA, Monsonego A, O'Banion MK, Pekny M, Puschmann T, Russek-Blum N, Sandusky LA, Selenica ML, Takata K, Teeling J, Town T, Van Eldik LJ.

J Neurochem. 2016 Sep;138(5):653-93. doi: 10.1111/jnc.13667. Review. Erratum in: J Neurochem. 2017 Apr;141(1):151.

6.

Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease.

Paul J, Strickland S, Melchor JP.

J Exp Med. 2007 Aug 6;204(8):1999-2008. Epub 2007 Jul 30.

7.

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation.

Ryu JK, Petersen MA, Murray SG, Baeten KM, Meyer-Franke A, Chan JP, Vagena E, Bedard C, Machado MR, Rios Coronado PE, Prod'homme T, Charo IF, Lassmann H, Degen JL, Zamvil SS, Akassoglou K.

Nat Commun. 2015 Sep 10;6:8164. doi: 10.1038/ncomms9164.

8.

Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration.

Cortes-Canteli M, Mattei L, Richards AT, Norris EH, Strickland S.

Neurobiol Aging. 2015 Feb;36(2):608-17. doi: 10.1016/j.neurobiolaging.2014.10.030. Epub 2014 Oct 31.

9.

Th17 cell-mediated neuroinflammation is involved in neurodegeneration of aβ1-42-induced Alzheimer's disease model rats.

Zhang J, Ke KF, Liu Z, Qiu YH, Peng YP.

PLoS One. 2013 Oct 4;8(10):e75786. doi: 10.1371/journal.pone.0075786. eCollection 2013.

11.

Inflammation in neurodegenerative diseases.

Amor S, Puentes F, Baker D, van der Valk P.

Immunology. 2010 Feb;129(2):154-69. doi: 10.1111/j.1365-2567.2009.03225.x. Review.

13.

Accessibility of epitopes on fibrin clots and fibrinogen gels.

Procyk R, Kudryk B, Callender S, Blombäck B.

Blood. 1991 Apr 1;77(7):1469-75.

14.

Innate immunity and neuroinflammation.

Shastri A, Bonifati DM, Kishore U.

Mediators Inflamm. 2013;2013:342931. doi: 10.1155/2013/342931. Epub 2013 Jun 15. Review.

15.

Role of Immunity and Inflammation in the Pathophysiology of Neurodegenerative Diseases.

Fakhoury M.

Neurodegener Dis. 2015;15(2):63-9. doi: 10.1159/000369933. Epub 2015 Jan 15. Review.

PMID:
25591815
16.

Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.

Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, Mucke L, Nelson RB, Akassoglou K.

Neuron. 2019 Mar 20;101(6):1099-1108.e6. doi: 10.1016/j.neuron.2019.01.014. Epub 2019 Feb 5.

PMID:
30737131
17.

Neurodegeneration and inflammation.

DeLegge MH, Smoke A.

Nutr Clin Pract. 2008 Feb;23(1):35-41. Review.

PMID:
18203962
18.

Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interaction.

Chung YC, Kruyer A, Yao Y, Feierman E, Richards A, Strickland S, Norris EH.

J Thromb Haemost. 2016 Jul;14(7):1442-52. doi: 10.1111/jth.13340. Epub 2016 Jun 13.

19.

Adaptive Immunity in Neurodegenerative and Neuropsychological Disorders.

Mosley RL.

J Neuroimmune Pharmacol. 2015 Dec;10(4):522-7. doi: 10.1007/s11481-015-9640-y. Epub 2015 Oct 26. Review.

PMID:
26496777
20.

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