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Items: 1 to 20 of 90

1.

Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways.

Miles MA, Hawkins CJ.

Sci Rep. 2018 Sep 26;8(1):14421. doi: 10.1038/s41598-018-32517-9.

2.

Topoisomerase II-mediated DNA damage is differently repaired during the cell cycle by non-homologous end joining and homologous recombination.

de Campos-Nebel M, Larripa I, González-Cid M.

PLoS One. 2010 Sep 2;5(9). pii: e12541. doi: 10.1371/journal.pone.0012541.

3.
4.

Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity.

Smith S, Fox J, Mejia M, Ruangpradit W, Saberi A, Kim S, Choi Y, Oh S, Wang Y, Choi K, Li L, Hendrickson EA, Takeda S, Muller M, Myung K.

PLoS One. 2014 Jan 23;9(1):e87203. doi: 10.1371/journal.pone.0087203. eCollection 2014.

5.

Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP).

Rosen DB, Leung LY, Louie B, Cordeiro JA, Conroy A, Shapira I, Fields SZ, Cesano A, Hawtin RE.

J Transl Med. 2014 Jun 25;12:184. doi: 10.1186/1479-5876-12-184.

6.

DNA-PKcs and ATM co-regulate DNA double-strand break repair.

Shrivastav M, Miller CA, De Haro LP, Durant ST, Chen BP, Chen DJ, Nickoloff JA.

DNA Repair (Amst). 2009 Aug 6;8(8):920-9. doi: 10.1016/j.dnarep.2009.05.006. Epub 2009 Jun 16.

7.

TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells.

Miles MA, Shekhar TM, Hall NE, Hawkins CJ.

Mutat Res. 2016 May;787:15-31. doi: 10.1016/j.mrfmmm.2016.02.006. Epub 2016 Feb 18.

PMID:
26943263
8.

Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors.

Riabinska A, Daheim M, Herter-Sprie GS, Winkler J, Fritz C, Hallek M, Thomas RK, Kreuzer KA, Frenzel LP, Monfared P, Martins-Boucas J, Chen S, Reinhardt HC.

Sci Transl Med. 2013 Jun 12;5(189):189ra78. doi: 10.1126/scitranslmed.3005814.

9.

Wortmannin potentiates the combined effect of etoposide and cisplatin in human glioma cells.

Pastwa E, Poplawski T, Lewandowska U, Somiari SB, Blasiak J, Somiari RI.

Int J Biochem Cell Biol. 2014 Aug;53:423-31. doi: 10.1016/j.biocel.2014.06.007. Epub 2014 Jun 19.

PMID:
24953561
11.
13.

Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway.

Okayasu R, Okada M, Okabe A, Noguchi M, Takakura K, Takahashi S.

Radiat Res. 2006 Jan;165(1):59-67.

PMID:
16392963
14.

DNA repair and chromosomal alterations.

Natarajan AT, Palitti F.

Mutat Res. 2008 Nov 17;657(1):3-7. doi: 10.1016/j.mrgentox.2008.08.017. Epub 2008 Aug 29. Review.

PMID:
18801460
15.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016. Epub 2009 Jul 5.

PMID:
19583974
16.

The controlling role of ATM in homologous recombinational repair of DNA damage.

Morrison C, Sonoda E, Takao N, Shinohara A, Yamamoto K, Takeda S.

EMBO J. 2000 Feb 1;19(3):463-71. Erratum in: EMBO J 2000 Feb 15;19(4):786.

17.

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells.

Shekhar TM, Green MM, Rayner DM, Miles MA, Cutts SM, Hawkins CJ.

Mutat Res. 2015 Jul;777:23-32. doi: 10.1016/j.mrfmmm.2015.04.005. Epub 2015 Apr 15.

PMID:
25916945
18.

Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.

Adachi N, Iiizumi S, So S, Koyama H.

Biochem Biophys Res Commun. 2004 Jun 11;318(4):856-61.

PMID:
15147950
19.

Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs-deficient context.

Palmitelli M, de Campos-Nebel M, González-Cid M.

Chromosome Res. 2015 Dec;23(4):719-32. doi: 10.1007/s10577-015-9478-4. Epub 2015 Jul 8.

PMID:
26152239
20.

Investigations on the role of base excision repair and non-homologous end-joining pathways in sodium selenite-induced toxicity and mutagenicity in Saccharomyces cerevisiae.

Mániková D, Vlasáková D, Loduhová J, Letavayová L, Vigasová D, Krascsenitsová E, Vlcková V, Brozmanová J, Chovanec M.

Mutagenesis. 2010 Mar;25(2):155-62. doi: 10.1093/mutage/gep056. Epub 2009 Dec 2.

PMID:
19955329

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