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Items: 1 to 20 of 96

1.

Common DNA Variants Accurately Rank an Individual of Extreme Height.

Sexton CE, Ebbert MTW, Miller RH, Ferrel M, Tschanz JAT, Corcoran CD; Alzheimer's Disease Neuroimaging Initiative , Ridge PG, Kauwe JSK.

Int J Genomics. 2018 Sep 4;2018:5121540. doi: 10.1155/2018/5121540. eCollection 2018.

2.

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals.

Chan Y, Holmen OL, Dauber A, Vatten L, Havulinna AS, Skorpen F, Kvaløy K, Silander K, Nguyen TT, Willer C, Boehnke M, Perola M, Palotie A, Salomaa V, Hveem K, Frayling TM, Hirschhorn JN, Weedon MN.

PLoS Genet. 2011 Dec;7(12):e1002439. doi: 10.1371/journal.pgen.1002439. Epub 2011 Dec 29.

3.

Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults.

Chen F, He J, Zhang J, Chen GK, Thomas V, Ambrosone CB, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Cai Q, Carpten J, Casey G, Chanock SJ, Cheng I, Chu L, Deming SL, Driver WR, Goodman P, Hayes RB, Hennis AJ, Hsing AW, Hu JJ, Ingles SA, John EM, Kittles RA, Kolb S, Leske MC, Millikan RC, Monroe KR, Murphy A, Nemesure B, Neslund-Dudas C, Nyante S, Ostrander EA, Press MF, Rodriguez-Gil JL, Rybicki BA, Schumacher F, Stanford JL, Signorello LB, Strom SS, Stevens V, Van Den Berg D, Wang Z, Witte JS, Wu SY, Yamamura Y, Zheng W, Ziegler RG, Stram AH, Kolonel LN, Le Marchand L, Henderson BE, Haiman CA, Stram DO.

PLoS One. 2015 Jun 30;10(6):e0131106. doi: 10.1371/journal.pone.0131106. eCollection 2015.

4.

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN.

Nature. 2010 Oct 14;467(7317):832-8. doi: 10.1038/nature09410. Epub 2010 Sep 29.

5.

Common DNA variants predict tall stature in Europeans.

Liu F, Hendriks AE, Ralf A, Boot AM, Benyi E, Sävendahl L, Oostra BA, van Duijn C, Hofman A, Rivadeneira F, Uitterlinden AG, Drop SL, Kayser M.

Hum Genet. 2014 May;133(5):587-97. doi: 10.1007/s00439-013-1394-0. Epub 2013 Nov 20.

PMID:
24253421
6.

Incorporating Functional Genomic Information to Enhance Polygenic Signal and Identify Variants Involved in Gene-by-Environment Interaction for Young Adult Alcohol Problems.

Salvatore JE, Savage JE, Barr P, Wolen AR, Aliev F, Vuoksimaa E, Latvala A, Pulkkinen L, Rose RJ, Kaprio J, Dick DM.

Alcohol Clin Exp Res. 2018 Feb;42(2):413-423. doi: 10.1111/acer.13551. Epub 2017 Dec 19.

7.

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.

Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O'Donovan MC, Kendler KS, Fanous AH; Schizophrenia Working Group of the Psychiatric Genomics Consortium.

Am J Med Genet B Neuropsychiatr Genet. 2016 Mar;171B(2):276-89. doi: 10.1002/ajmg.b.32402. Epub 2015 Dec 11.

8.

Trans-Ethnic Polygenic Analysis Supports Genetic Overlaps of Lumbar Disc Degeneration With Height, Body Mass Index, and Bone Mineral Density.

Zhou X, Cheung CL, Karasugi T, Karppinen J, Samartzis D, Hsu YH, Mak TS, Song YQ, Chiba K, Kawaguchi Y, Li Y, Chan D, Cheung KM, Ikegawa S, Cheah KS, Sham PC.

Front Genet. 2018 Aug 3;9:267. doi: 10.3389/fgene.2018.00267. eCollection 2018.

9.

Genome-wide compound heterozygote analysis highlights alleles associated with adult height in Europeans.

Zhong K, Zhu G, Jing X, Hendriks AEJ, Drop SLS, Ikram MA, Gordon S, Zeng C, Uitterlinden AG, Martin NG, Liu F, Kayser M.

Hum Genet. 2017 Nov;136(11-12):1407-1417. doi: 10.1007/s00439-017-1842-3. Epub 2017 Sep 18.

10.

Signatures of natural selection on genetic variants affecting complex human traits.

Zhang G, Muglia LJ, Chakraborty R, Akey JM, Williams SM.

Appl Transl Genom. 2013 Nov 7;2:78-94. eCollection 2013 Dec 1.

11.

Using height association studies to gain insights into human idiopathic short and syndromic stature phenotypes.

Lettre G.

Pediatr Nephrol. 2013 Apr;28(4):557-62. doi: 10.1007/s00467-012-2301-y. Epub 2012 Sep 2. Review.

PMID:
22941042
12.

Polygenic risk scores in imaging genetics: Usefulness and applications.

Dima D, Breen G.

J Psychopharmacol. 2015 Aug;29(8):867-71. doi: 10.1177/0269881115584470. Epub 2015 May 5. Review.

PMID:
25944849
13.

Schizophrenia polygenic risk score predicts mnemonic hippocampal activity.

Chen Q, Ursini G, Romer AL, Knodt AR, Mezeivtch K, Xiao E, Pergola G, Blasi G, Straub RE, Callicott JH, Berman KF, Hariri AR, Bertolino A, Mattay VS, Weinberger DR.

Brain. 2018 Apr 1;141(4):1218-1228. doi: 10.1093/brain/awy004.

14.

Polygenic influences on dyslipidemias.

Dron JS, Hegele RA.

Curr Opin Lipidol. 2018 Apr;29(2):133-143. doi: 10.1097/MOL.0000000000000482.

PMID:
29300201
15.

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.

Fanous AH, Zhou B, Aggen SH, Bergen SE, Amdur RL, Duan J, Sanders AR, Shi J, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, Freedman R, Dudbridge F, Holmans PA, Ripke S, Gejman PV, Kendler KS, Levinson DF; Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium.

Am J Psychiatry. 2012 Dec;169(12):1309-17. doi: 10.1176/appi.ajp.2012.12020218.

16.

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

Cross-Disorder Group of the Psychiatric Genomics Consortium.

Lancet. 2013 Apr 20;381(9875):1371-1379. doi: 10.1016/S0140-6736(12)62129-1. Epub 2013 Feb 28. Erratum in: Lancet. 2013 Apr 20;381(9875):1360. Erratum in: Lancet. 2013 Apr 20;381(9875):1360.

17.

Common polygenic variation contributes to risk of migraine in the Norfolk Island population.

Rodriguez-Acevedo AJ, Ferreira MA, Benton MC, Carless MA, Goring HH, Curran JE, Blangero J, Lea RA, Griffiths LR.

Hum Genet. 2015 Oct;134(10):1079-87. doi: 10.1007/s00439-015-1587-9. Epub 2015 Jul 29.

PMID:
26220684
18.

Variability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway.

Nicodemus KK, Hargreaves A, Morris D, Anney R; Schizophrenia Psychiatric Genome-wide Association Study (GWAS) Consortium; Wellcome Trust Case Control Consortium 2, Gill M, Corvin A, Donohoe G.

JAMA Psychiatry. 2014 Jul 1;71(7):778-785. doi: 10.1001/jamapsychiatry.2014.528.

19.

Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes.

Andreassen OA, McEvoy LK, Thompson WK, Wang Y, Reppe S, Schork AJ, Zuber V, Barrett-Connor E, Gautvik K, Aukrust P, Karlsen TH, Djurovic S, Desikan RS, Dale AM; International Consortium for Blood Pressure Genome-Wide Association Studies, Genetic Factors for Osteoporosis Consortium.

Hypertension. 2014 Apr;63(4):819-26. doi: 10.1161/HYPERTENSIONAHA.113.02077. Epub 2014 Jan 6.

20.

Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies.

Sohail M, Maier RM, Ganna A, Bloemendal A, Martin AR, Turchin MC, Chiang CW, Hirschhorn J, Daly MJ, Patterson N, Neale B, Mathieson I, Reich D, Sunyaev SR.

Elife. 2019 Mar 21;8. pii: e39702. doi: 10.7554/eLife.39702.

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