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Items: 1 to 20 of 98

1.

Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom.

Lewin MR, Gutiérrez JM, Samuel SP, Herrera M, Bryan-Quirós W, Lomonte B, Bickler PE, Bulfone TC, Williams DJ.

Toxins (Basel). 2018 Sep 20;10(10). pii: E380. doi: 10.3390/toxins10100380.

2.

Delayed LY333013 (Oral) and LY315920 (Intravenous) Reverse Severe Neurotoxicity and Rescue Juvenile Pigs from Lethal Doses of Micrurus fulvius (Eastern Coral Snake) Venom.

Lewin MR, Gilliam LL, Gilliam J, Samuel SP, Bulfone TC, Bickler PE, Gutiérrez JM.

Toxins (Basel). 2018 Nov 17;10(11). pii: E479. doi: 10.3390/toxins10110479.

4.

Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea.

Vargas M, Segura A, Herrera M, Villalta M, Estrada R, Cerdas M, Paiva O, Matainaho T, Jensen SD, Winkel KD, León G, Gutiérrez JM, Williams DJ.

PLoS Negl Trop Dis. 2011 May;5(5):e1144. doi: 10.1371/journal.pntd.0001144. Epub 2011 May 17.

5.

Australian taipan (Oxyuranus spp.) envenoming: clinical effects and potential benefits of early antivenom therapy - Australian Snakebite Project (ASP-25).

Johnston CI, Ryan NM, O'Leary MA, Brown SG, Isbister GK.

Clin Toxicol (Phila). 2017 Feb;55(2):115-122. doi: 10.1080/15563650.2016.1250903. Epub 2016 Nov 30.

PMID:
27903075
6.

Hypotensive and vascular relaxant effects of phospholipase A2 toxins from Papuan taipan (Oxyuranus scutellatus) venom.

Chaisakul J, Isbister GK, Tare M, Parkington HC, Hodgson WC.

Eur J Pharmacol. 2014 Jan 15;723:227-33. doi: 10.1016/j.ejphar.2013.11.028. Epub 2013 Dec 1.

PMID:
24296315
7.

Isolation and pharmacological characterization of cannitoxin, a presynaptic neurotoxin from the venom of the Papuan Taipan (Oxyuranus scutellatus canni).

Kuruppu S, Reeve S, Banerjee Y, Kini RM, Smith AI, Hodgson WC.

J Pharmacol Exp Ther. 2005 Dec;315(3):1196-202. Epub 2005 Aug 31.

PMID:
16135698
8.
9.

The efficacy of antivenom in the treatment of bites by the Papuan taipan (Oxyuranus scutellatus canni).

Trevett AJ, Lalloo DG, Nwokolo NC, Naraqi S, Kevau IH, Theakston RD, Warrell DA.

Trans R Soc Trop Med Hyg. 1995 May-Jun;89(3):322-5.

PMID:
7660450
10.

Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom.

Zdenek CN, Hay C, Arbuckle K, Jackson TNW, Bos MHA, Op den Brouw B, Debono J, Allen L, Dunstan N, Morley T, Herrera M, Gutiérrez JM, Williams DJ, Fry BG.

Toxicol In Vitro. 2019 Mar 22;58:97-109. doi: 10.1016/j.tiv.2019.03.031. [Epub ahead of print]

PMID:
30910521
11.

Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom.

Navarro D, Vargas M, Herrera M, Segura Á, Gómez A, Villalta M, Ramírez N, Williams D, Gutiérrez JM, León G.

Toxicon. 2016 Sep 15;120:1-8. doi: 10.1016/j.toxicon.2016.06.018. Epub 2016 Jun 29.

PMID:
27373994
12.

Snake bites by the Papuan taipan (Oxyuranus scutellatus canni): paralysis, hemostatic and electrocardiographic abnormalities, and effects of antivenom.

Lalloo DG, Trevett AJ, Korinhona A, Nwokolo N, Laurenson IF, Paul M, Black J, Naraqi S, Mavo B, Saweri A, et al.

Am J Trop Med Hyg. 1995 Jun;52(6):525-31.

PMID:
7611559
13.

Comparative studies of the venom of a new Taipan species, Oxyuranus temporalis, with other members of its genus.

Barber CM, Madaras F, Turnbull RK, Morley T, Dunstan N, Allen L, Kuchel T, Mirtschin P, Hodgson WC.

Toxins (Basel). 2014 Jul 2;6(7):1979-95. doi: 10.3390/toxins6071979.

14.

Differential myotoxic and cytotoxic activities of pre-synaptic neurotoxins from Papuan taipan (Oxyuranus scutellatus) and Irian Jayan death adder (Acanthophis rugosus) venoms.

Chaisakul J, Parkington HC, Isbister GK, Konstantakopoulos N, Hodgson WC.

Basic Clin Pharmacol Toxicol. 2013 May;112(5):325-34. doi: 10.1111/bcpt.12048. Epub 2013 Feb 23.

15.

Variations in the pharmacological profile of post-synaptic neurotoxins isolated from the venoms of the Papuan (Oxyuranus scutellatus canni) and coastal (Oxyuranus scutellatus scutellatus) taipans.

Kornhauser R, Hart AJ, Reeve S, Smith AI, Fry BG, Hodgson WC.

Neurotoxicology. 2010 Mar;31(2):239-43. doi: 10.1016/j.neuro.2009.12.009. Epub 2009 Dec 29.

PMID:
20036687
16.

In vivo and in vitro cardiovascular effects of Papuan taipan (Oxyuranus scutellatus) venom: Exploring "sudden collapse".

Chaisakul J, Isbister GK, Konstantakopoulos N, Tare M, Parkington HC, Hodgson WC.

Toxicol Lett. 2012 Sep 3;213(2):243-8. doi: 10.1016/j.toxlet.2012.06.015. Epub 2012 Jul 3.

PMID:
22771951
18.

An examination of cardiovascular collapse induced by eastern brown snake (Pseudonaja textilis) venom.

Chaisakul J, Isbister GK, Kuruppu S, Konstantakopoulos N, Hodgson WC.

Toxicol Lett. 2013 Aug 29;221(3):205-11. doi: 10.1016/j.toxlet.2013.06.235. Epub 2013 Jul 2.

PMID:
23830990
19.

Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab')2 and whole IgG antivenoms.

Herrera M, de Cássia de O Collaço R, Villalta M, Segura Á, Vargas M, Wright CE, Paiva OK, Matainaho T, Jensen SD, León G, Williams DJ, Rodrigues-Simioni L, Gutiérrez JM.

Toxicol Lett. 2016 Jan 22;241:175-83. doi: 10.1016/j.toxlet.2015.11.020. Epub 2015 Nov 24.

PMID:
26621539
20.

Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite.

Bulfone TC, Samuel SP, Bickler PE, Lewin MR.

J Trop Med. 2018 Jul 30;2018:4320175. doi: 10.1155/2018/4320175. eCollection 2018. Review.

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