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Items: 1 to 20 of 105

1.

TMEM41B is a novel regulator of autophagy and lipid mobilization.

Moretti F, Bergman P, Dodgson S, Marcellin D, Claerr I, Goodwin JM, DeJesus R, Kang Z, Antczak C, Begue D, Bonenfant D, Graff A, Genoud C, Reece-Hoyes JS, Russ C, Yang Z, Hoffman GR, Mueller M, Murphy LO, Xavier RJ, Nyfeler B.

EMBO Rep. 2018 Sep;19(9). pii: e45889. doi: 10.15252/embr.201845889. Epub 2018 Aug 20.

PMID:
30126924
2.

Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation.

Morita K, Hama Y, Izume T, Tamura N, Ueno T, Yamashita Y, Sakamaki Y, Mimura K, Morishita H, Shihoya W, Nureki O, Mano H, Mizushima N.

J Cell Biol. 2018 Nov 5;217(11):3817-3828. doi: 10.1083/jcb.201804132. Epub 2018 Aug 9.

PMID:
30093494
3.

TMEM41B functions with VMP1 in autophagosome formation.

Morita K, Hama Y, Mizushima N.

Autophagy. 2019 May;15(5):922-923. doi: 10.1080/15548627.2019.1582952. Epub 2019 Feb 26.

PMID:
30773971
4.

CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor.

Shoemaker CJ, Huang TQ, Weir NR, Polyakov NJ, Schultz SW, Denic V.

PLoS Biol. 2019 Apr 1;17(4):e2007044. doi: 10.1371/journal.pbio.2007044. eCollection 2019 Apr.

5.

Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation.

Bansal M, Moharir SC, Swarup G.

Commun Integr Biol. 2018 May 17;11(2):1-4. doi: 10.1080/19420889.2018.1467189. eCollection 2018.

6.

Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein.

Bansal M, Moharir SC, Sailasree SP, Sirohi K, Sudhakar C, Sarathi DP, Lakshmi BJ, Buono M, Kumar S, Swarup G.

J Biol Chem. 2018 Jan 5;293(1):132-147. doi: 10.1074/jbc.M117.801944. Epub 2017 Nov 13.

7.

Mechanisms of Selective Autophagy.

Zaffagnini G, Martens S.

J Mol Biol. 2016 May 8;428(9 Pt A):1714-24. doi: 10.1016/j.jmb.2016.02.004. Epub 2016 Feb 12. Review.

8.

Visualization of reticulophagy in living cells using an endoplasmic reticulum-targeted p62 mutant.

Wang L, Liu L, Qin L, Luo Q, Zhang Z.

Sci China Life Sci. 2017 Apr;60(4):333-344. doi: 10.1007/s11427-015-9037-4. Epub 2017 Apr 13.

PMID:
28424968
9.

Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis.

Chen X, Li M, Chen D, Gao W, Guan JL, Komatsu M, Yin XM.

PLoS One. 2012;7(12):e52347. doi: 10.1371/journal.pone.0052347. Epub 2012 Dec 21.

10.

Autophagy regulation depends on ER homeostasis controlled by lipid droplets.

Velázquez AP, Graef M.

Autophagy. 2016 Aug 2;12(8):1409-10. doi: 10.1080/15548627.2016.1190074. Epub 2016 May 31.

11.

Lipid-Induced Endoplasmic Reticulum Stress Impairs Selective Autophagy at the Step of Autophagosome-Lysosome Fusion in Hepatocytes.

Miyagawa K, Oe S, Honma Y, Izumi H, Baba R, Harada M.

Am J Pathol. 2016 Jul;186(7):1861-1873. doi: 10.1016/j.ajpath.2016.03.003. Epub 2016 May 6.

PMID:
27157992
12.

Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure.

Corcelle-Termeau E, Vindeløv SD, Hämälistö S, Mograbi B, Keldsbo A, Bräsen JH, Favaro E, Adam D, Szyniarowski P, Hofman P, Krautwald S, Farkas T, Petersen NH, Rohde M, Linkermann A, Jäättelä M.

Autophagy. 2016 May 3;12(5):833-49. doi: 10.1080/15548627.2016.1159378. Epub 2016 Apr 12.

13.

The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A.

Puri C, Vicinanza M, Ashkenazi A, Gratian MJ, Zhang Q, Bento CF, Renna M, Menzies FM, Rubinsztein DC.

Dev Cell. 2018 Apr 9;45(1):114-131.e8. doi: 10.1016/j.devcel.2018.03.008.

14.

Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains.

Nishimura T, Tamura N, Kono N, Shimanaka Y, Arai H, Yamamoto H, Mizushima N.

EMBO J. 2017 Jun 14;36(12):1719-1735. doi: 10.15252/embj.201695189. Epub 2017 May 11.

15.

Autophagosomes form at ER-mitochondria contact sites.

Hamasaki M, Furuta N, Matsuda A, Nezu A, Yamamoto A, Fujita N, Oomori H, Noda T, Haraguchi T, Hiraoka Y, Amano A, Yoshimori T.

Nature. 2013 Mar 21;495(7441):389-93. doi: 10.1038/nature11910. Epub 2013 Mar 3.

PMID:
23455425
16.

Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis.

Dupont N, Chauhan S, Arko-Mensah J, Castillo EF, Masedunskas A, Weigert R, Robenek H, Proikas-Cezanne T, Deretic V.

Curr Biol. 2014 Mar 17;24(6):609-20. doi: 10.1016/j.cub.2014.02.008. Epub 2014 Mar 6.

17.

The Journey of the Autophagosome through Mammalian Cell Organelles and Membranes.

Molino D, Zemirli N, Codogno P, Morel E.

J Mol Biol. 2017 Feb 17;429(4):497-514. doi: 10.1016/j.jmb.2016.12.013. Epub 2016 Dec 13. Review.

PMID:
27986571
18.

p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.

Itakura E, Mizushima N.

J Cell Biol. 2011 Jan 10;192(1):17-27. doi: 10.1083/jcb.201009067.

19.

WIPI β-propellers at the crossroads of autophagosome and lipid droplet dynamics.

Pfisterer SG, Bakula D, Cezanne A, Robenek H, Proikas-Cezanne T.

Biochem Soc Trans. 2014 Oct;42(5):1414-7. doi: 10.1042/BST20140152.

PMID:
25233424
20.

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

Van Alstyne M, Lotti F, Dal Mas A, Area-Gomez E, Pellizzoni L.

Biochem Biophys Res Commun. 2018 Nov 30;506(3):463-470. doi: 10.1016/j.bbrc.2018.10.073. Epub 2018 Oct 22.

PMID:
30352685

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