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Items: 1 to 20 of 104

1.

The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease.

Chambers ES, Byrne CS, Rugyendo A, Morrison DJ, Preston T, Tedford C, Bell JD, Thomas L, Akbar AN, Riddell NE, Sharma R, Thursz MR, Manousou P, Frost G.

Diabetes Obes Metab. 2019 Feb;21(2):372-376. doi: 10.1111/dom.13500. Epub 2018 Sep 16.

PMID:
30098126
2.

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial.

Chambers ES, Byrne CS, Morrison DJ, Murphy KG, Preston T, Tedford C, Garcia-Perez I, Fountana S, Serrano-Contreras JI, Holmes E, Reynolds CJ, Roberts JF, Boyton RJ, Altmann DM, McDonald JAK, Marchesi JR, Akbar AN, Riddell NE, Wallis GA, Frost GS.

Gut. 2019 Apr 10. pii: gutjnl-2019-318424. doi: 10.1136/gutjnl-2019-318424. [Epub ahead of print]

3.

Randomised clinical study: inulin short-chain fatty acid esters for targeted delivery of short-chain fatty acids to the human colon.

Polyviou T, MacDougall K, Chambers ES, Viardot A, Psichas A, Jawaid S, Harris HC, Edwards CA, Simpson L, Murphy KG, Zac-Varghese SE, Blundell JE, Dhillo WS, Bloom SR, Frost GS, Preston T, Tedford MC, Morrison DJ.

Aliment Pharmacol Ther. 2016 Oct;44(7):662-72. doi: 10.1111/apt.13749. Epub 2016 Jul 28.

4.

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults.

Chambers ES, Viardot A, Psichas A, Morrison DJ, Murphy KG, Zac-Varghese SE, MacDougall K, Preston T, Tedford C, Finlayson GS, Blundell JE, Bell JD, Thomas EL, Mt-Isa S, Ashby D, Gibson GR, Kolida S, Dhillo WS, Bloom SR, Morley W, Clegg S, Frost G.

Gut. 2015 Nov;64(11):1744-54. doi: 10.1136/gutjnl-2014-307913. Epub 2014 Dec 10.

5.

Quantification of in Vivo Colonic Short Chain Fatty Acid Production from Inulin.

Boets E, Deroover L, Houben E, Vermeulen K, Gomand SV, Delcour JA, Verbeke K.

Nutrients. 2015 Oct 28;7(11):8916-29. doi: 10.3390/nu7115440.

6.

Effects of dietary inulin on bacterial growth, short-chain fatty acid production and hepatic lipid metabolism in gnotobiotic mice.

Weitkunat K, Schumann S, Petzke KJ, Blaut M, Loh G, Klaus S.

J Nutr Biochem. 2015 Sep;26(9):929-37. doi: 10.1016/j.jnutbio.2015.03.010. Epub 2015 May 1.

PMID:
26033744
7.

Short-chain fatty acids and inulin, but not guar gum, prevent diet-induced obesity and insulin resistance through differential mechanisms in mice.

Weitkunat K, Stuhlmann C, Postel A, Rumberger S, Fankhänel M, Woting A, Petzke KJ, Gohlke S, Schulz TJ, Blaut M, Klaus S, Schumann S.

Sci Rep. 2017 Jul 21;7(1):6109. doi: 10.1038/s41598-017-06447-x.

8.
9.

Inulin increases short-term markers for colonic fermentation similarly in healthy and hyperinsulinaemic humans.

Fernandes J, Vogt J, Wolever TM.

Eur J Clin Nutr. 2011 Dec;65(12):1279-86. doi: 10.1038/ejcn.2011.116. Epub 2011 Jun 29.

10.

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men.

van der Beek CM, Canfora EE, Kip AM, Gorissen SHM, Olde Damink SWM, van Eijk HM, Holst JJ, Blaak EE, Dejong CHC, Lenaerts K.

Metabolism. 2018 Oct;87:25-35. doi: 10.1016/j.metabol.2018.06.009. Epub 2018 Jun 25.

PMID:
29953876
11.

L-rhamnose as a source of colonic propionate inhibits insulin secretion but does not influence measures of appetite or food intake.

Darzi J, Frost GS, Swann JR, Costabile A, Robertson MD.

Appetite. 2016 Mar 1;98:142-9. doi: 10.1016/j.appet.2015.12.011. Epub 2015 Dec 17.

PMID:
26706043
12.

Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate.

Weitkunat K, Schumann S, Nickel D, Hornemann S, Petzke KJ, Schulze MB, Pfeiffer AF, Klaus S.

Am J Clin Nutr. 2017 Jun;105(6):1544-1551. doi: 10.3945/ajcn.117.152702. Epub 2017 Apr 19.

PMID:
28424190
13.

The impact of long-term dietary pattern of fecal donor on in vitro fecal fermentation properties of inulin.

Yang J, Rose DJ.

Food Funct. 2016 Apr;7(4):1805-13. doi: 10.1039/c5fo00987a.

PMID:
26583778
14.

Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods.

Byrne CS, Chambers ES, Alhabeeb H, Chhina N, Morrison DJ, Preston T, Tedford C, Fitzpatrick J, Irani C, Busza A, Garcia-Perez I, Fountana S, Holmes E, Goldstone AP, Frost GS.

Am J Clin Nutr. 2016 Jul;104(1):5-14. doi: 10.3945/ajcn.115.126706. Epub 2016 May 11.

15.

The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro.

Pingitore A, Chambers ES, Hill T, Maldonado IR, Liu B, Bewick G, Morrison DJ, Preston T, Wallis GA, Tedford C, Castañera González R, Huang GC, Choudhary P, Frost G, Persaud SJ.

Diabetes Obes Metab. 2017 Feb;19(2):257-265. doi: 10.1111/dom.12811. Epub 2016 Nov 23.

PMID:
27761989
16.

Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice.

Marques TM, Wall R, O'Sullivan O, Fitzgerald GF, Shanahan F, Quigley EM, Cotter PD, Cryan JF, Dinan TG, Ross RP, Stanton C.

Br J Nutr. 2015 Mar 14;113(5):728-38. doi: 10.1017/S0007114514004206. Epub 2015 Feb 20.

PMID:
25697178
17.

Effect of acetate and propionate on fasting hepatic glucose production in humans.

Laurent C, Simoneau C, Marks L, Braschi S, Champ M, Charbonnel B, Krempf M.

Eur J Clin Nutr. 1995 Jul;49(7):484-91.

PMID:
7588498
18.

Effects of dietary propionate on hepatic glucose production, whole-body glucose utilization, carbohydrate and lipid metabolism in normal rats.

Boillot J, Alamowitch C, Berger AM, Luo J, Bruzzo F, Bornet FR, Slama G.

Br J Nutr. 1995 Feb;73(2):241-51.

PMID:
7718543
19.

Wheat Bran Does Not Affect Postprandial Plasma Short-Chain Fatty Acids from 13C-inulin Fermentation in Healthy Subjects.

Deroover L, Verspreet J, Luypaerts A, Vandermeulen G, Courtin CM, Verbeke K.

Nutrients. 2017 Jan 20;9(1). pii: E83. doi: 10.3390/nu9010083.

20.

Habitual dietary fibre intake influences gut microbiota response to an inulin-type fructan prebiotic: a randomised, double-blind, placebo-controlled, cross-over, human intervention study.

Healey G, Murphy R, Butts C, Brough L, Whelan K, Coad J.

Br J Nutr. 2018 Jan;119(2):176-189. doi: 10.1017/S0007114517003440. Epub 2018 Jan 8.

PMID:
29307330

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