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Items: 1 to 20 of 102

1.

Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters.

McKinlay CJ, Benner NL, Haabeth OA, Waymouth RM, Wender PA.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5859-E5866. doi: 10.1073/pnas.1805358115. Epub 2018 Jun 11.

2.

Functional DNA Delivery Enabled by Lipid-Modified Charge-Altering Releasable Transporters (CARTs).

Benner NL, Near KE, Bachmann MH, Contag CH, Waymouth RM, Wender PA.

Biomacromolecules. 2018 Jul 9;19(7):2812-2824. doi: 10.1021/acs.biomac.8b00401. Epub 2018 May 11.

PMID:
29727572
3.

Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals.

McKinlay CJ, Vargas JR, Blake TR, Hardy JW, Kanada M, Contag CH, Wender PA, Waymouth RM.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E448-E456. doi: 10.1073/pnas.1614193114. Epub 2017 Jan 9.

4.

mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice.

Haabeth OAW, Blake TR, McKinlay CJ, Waymouth RM, Wender PA, Levy R.

Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9153-E9161. doi: 10.1073/pnas.1810002115. Epub 2018 Sep 10.

5.

Self-assembling complexes between binary mixtures of lipids with different linkers and nucleic acids promote universal mRNA, DNA and siRNA delivery.

Colombani T, Peuziat P, Dallet L, Haudebourg T, Mével M, Berchel M, Lambert O, Habrant D, Pitard B.

J Control Release. 2017 Mar 10;249:131-142. doi: 10.1016/j.jconrel.2017.01.041. Epub 2017 Feb 1.

PMID:
28159514
6.

Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs.

Kauffman KJ, Dorkin JR, Yang JH, Heartlein MW, DeRosa F, Mir FF, Fenton OS, Anderson DG.

Nano Lett. 2015 Nov 11;15(11):7300-6. doi: 10.1021/acs.nanolett.5b02497. Epub 2015 Oct 20.

PMID:
26469188
7.

In Vivo Introduction of mRNA Encapsulated in Lipid Nanoparticles to Brain Neuronal Cells and Astrocytes via Intracerebroventricular Administration.

Tanaka H, Nakatani T, Furihata T, Tange K, Nakai Y, Yoshioka H, Harashima H, Akita H.

Mol Pharm. 2018 May 7;15(5):2060-2067. doi: 10.1021/acs.molpharmaceut.7b01084. Epub 2018 Apr 11.

PMID:
29638135
8.

Non-Viral, Lipid-Mediated DNA and mRNA Gene Therapy of the Central Nervous System (CNS): Chemical-Based Transfection.

Hecker JG.

Methods Mol Biol. 2016;1382:307-24. doi: 10.1007/978-1-4939-3271-9_23.

PMID:
26611597
9.

Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA.

Ball RL, Hajj KA, Vizelman J, Bajaj P, Whitehead KA.

Nano Lett. 2018 Jun 13;18(6):3814-3822. doi: 10.1021/acs.nanolett.8b01101. Epub 2018 May 8.

PMID:
29694050
10.

Identification of novel superior polycationic vectors for gene delivery by high-throughput synthesis and screening of a combinatorial library.

Thomas M, Lu JJ, Zhang C, Chen J, Klibanov AM.

Pharm Res. 2007 Aug;24(8):1564-71. Epub 2007 Mar 24.

PMID:
17385014
11.

Optimized cationic lipid-based gene delivery reagents for use in developing vertebrate embryos.

Decastro M, Saijoh Y, Schoenwolf GC.

Dev Dyn. 2006 Aug;235(8):2210-9.

12.

Gemini surfactant dimethylene-1,2-bis(tetradecyldimethylammonium bromide)-based gene vectors: a biophysical approach to transfection efficiency.

Cardoso AM, Faneca H, Almeida JA, Pais AA, Marques EF, de Lima MC, Jurado AS.

Biochim Biophys Acta. 2011 Jan;1808(1):341-51. doi: 10.1016/j.bbamem.2010.09.026. Epub 2010 Oct 16.

13.

Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles.

Yasar H, Biehl A, De Rossi C, Koch M, Murgia X, Loretz B, Lehr CM.

J Nanobiotechnology. 2018 Sep 19;16(1):72. doi: 10.1186/s12951-018-0401-y.

14.

Analysis and optimization of the cationic lipid component of a lipid/peptide vector formulation for enhanced transfection in vitro and in vivo.

Writer M, Hurley CA, Sarkar S, Copeman DM, Wong JB, Odlyha M, Jayne Lawrence M, Tabor AB, McAnulty RJ, Ayazi Shamlou P, Hailes HC, Hart SL.

J Liposome Res. 2006;16(4):373-89.

PMID:
17162579
15.

Nonviral, cationic lipid-mediated delivery of mRNA.

Hecker JG.

Methods Mol Biol. 2013;969:73-88. doi: 10.1007/978-1-62703-260-5_5.

PMID:
23296928
16.

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy.

Oberli MA, Reichmuth AM, Dorkin JR, Mitchell MJ, Fenton OS, Jaklenec A, Anderson DG, Langer R, Blankschtein D.

Nano Lett. 2017 Mar 8;17(3):1326-1335. doi: 10.1021/acs.nanolett.6b03329. Epub 2016 Dec 5.

17.
18.

Combinational use of lipid-based reagents for efficient transfection of primary fibroblasts and hepatoblasts.

Ishiguro K, Watanabe O, Nakamura M, Yamamura T, Matsushita M, Goto H, Hirooka Y.

Biotechniques. 2017 Jul 1;63(1):37-39. doi: 10.2144/000114569.

19.

Charge-reversal lipids, peptide-based lipids, and nucleoside-based lipids for gene delivery.

LaManna CM, Lusic H, Camplo M, McIntosh TJ, Barthélémy P, Grinstaff MW.

Acc Chem Res. 2012 Jul 17;45(7):1026-38. doi: 10.1021/ar200228y. Epub 2012 Mar 22.

20.

Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level.

Ewert K, Slack NL, Ahmad A, Evans HM, Lin AJ, Samuel CE, Safinya CR.

Curr Med Chem. 2004 Jan;11(2):133-49. Review.

PMID:
14754413

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