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Items: 1 to 20 of 82


Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans.

Lutz SZ, Falcenberg M, Machicao F, Peter A, Kächele M, Randrianarisoa E, Lehn-Stefan A, Wagner R, Machann J, Schick F, Heni M, Ullrich A, Fritsche A, Stefan N, Häring HU, Staiger H, Kantartzis K.

Sci Rep. 2018 May 17;8(1):7745. doi: 10.1038/s41598-018-26055-7.


Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity.

Lutz SZ, Peter A, Machicao F, Lamprinou A, Machann J, Schick F, Königsrainer I, Königsrainer A, Fritsche A, Staiger H, Häring HU, Stefan N, Kantartzis K.

J Clin Endocrinol Metab. 2016 Dec;101(12):4743-4751. Epub 2016 Oct 7.


RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.

Müssig K, Staiger H, Machicao F, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Apr;58(4):519-24. doi: 10.1016/j.metabol.2008.11.011.


Visceral obesity modulates the impact of apolipoprotein C3 gene variants on liver fat content.

Peter A, Kantartzis K, Machicao F, Machann J, Wagner S, Templin S, Königsrainer I, Königsrainer A, Schick F, Fritsche A, Häring HU, Stefan N.

Int J Obes (Lond). 2012 Jun;36(6):774-82. doi: 10.1038/ijo.2011.154. Epub 2011 Aug 9.


GRK5 intronic (CA)n polymorphisms associated with type 2 diabetes in Chinese Hainan Island.

Xia Z, Yang T, Wang Z, Dong J, Liang C.

PLoS One. 2014 Mar 3;9(3):e90597. doi: 10.1371/journal.pone.0090597. eCollection 2014.


Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene-gene interactions.

Kantartzis K, Fritsche A, Machicao F, Stumvoll M, Machann J, Schick F, Häring HU, Stefan N.

J Mol Med (Berl). 2007 Jan;85(1):55-61. Epub 2006 Sep 26.


Genetic variation in NR1H4 encoding the bile acid receptor FXR determines fasting glucose and free fatty acid levels in humans.

Heni M, Wagner R, Ketterer C, Böhm A, Linder K, Machicao F, Machann J, Schick F, Hennige AM, Stefan N, Häring HU, Fritsche A, Staiger H.

J Clin Endocrinol Metab. 2013 Jul;98(7):E1224-9. doi: 10.1210/jc.2013-1177. Epub 2013 May 2.


Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers.

Kächele M, Hennige AM, Machann J, Hieronimus A, Lamprinou A, Machicao F, Schick F, Fritsche A, Stefan N, Nürnberg B, Häring HU, Staiger H.

PLoS One. 2015 Dec 10;10(12):e0144494. doi: 10.1371/journal.pone.0144494. eCollection 2015.


Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.

Kantartzis K, Peter A, Machicao F, Machann J, Wagner S, Königsrainer I, Königsrainer A, Schick F, Fritsche A, Häring HU, Stefan N.

Diabetes. 2009 Nov;58(11):2616-23. doi: 10.2337/db09-0279. Epub 2009 Aug 3.


Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.

Guo YF, Xiong DH, Shen H, Zhao LJ, Xiao P, Guo Y, Wang W, Yang TL, Recker RR, Deng HW.

J Med Genet. 2006 Oct;43(10):798-803. Epub 2006 May 24.


Microcirculatory damage of common carotid artery wall in obese and non obese subjects.

Ciccone M, Maiorano A, De Pergola G, Minenna A, Giorgino R, Rizzon P.

Clin Hemorheol Microcirc. 1999;21(3-4):365-74.


Specifically PNPLA3-mediated accumulation of liver fat in obese patients with type 2 diabetes.

Petit JM, Guiu B, Masson D, Duvillard L, Jooste V, Buffier P, Terriat B, Bouillet B, Brindisi MC, Loffroy R, Robin I, Hillon P, Cercueil JP, Verges B.

J Clin Endocrinol Metab. 2010 Dec;95(12):E430-6. doi: 10.1210/jc.2010-0814. Epub 2010 Sep 8.


Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients.

Lobmeyer MT, Wang L, Zineh I, Turner ST, Gums JG, Chapman AB, Cooper-DeHoff RM, Beitelshees AL, Bailey KR, Boerwinkle E, Pepine CJ, Johnson JA.

Pharmacogenet Genomics. 2011 Jan;21(1):42-9. doi: 10.1097/FPC.0b013e328341e911.


The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies.

Weyrich P, Staiger H, Stančáková A, Machicao F, Machann J, Schick F, Stefan N, Kuusisto J, Laakso M, Schäfer S, Fritsche A, Häring HU.

PLoS One. 2010 Nov 15;5(11):e13980. doi: 10.1371/journal.pone.0013980.


Categorical complexities of Plasmodium falciparum malaria in individuals is associated with genetic variations in ADORA2A and GRK5 genes.

Gupta H, Jain A, Saadi AV, Vasudevan TG, Hande MH, D'Souza SC, Ghosh SK, Umakanth S, Satyamoorthy K.

Infect Genet Evol. 2015 Aug;34:188-99. doi: 10.1016/j.meegid.2015.06.010. Epub 2015 Jun 9.


Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.

Haupt A, Thamer C, Heni M, Machicao F, Machann J, Schick F, Stefan N, Fritsche A, Häring HU, Staiger H.

Obesity (Silver Spring). 2010 Jun;18(6):1212-7. doi: 10.1038/oby.2009.413. Epub 2009 Nov 12.


Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: a case-control study in Chinese population.

Gu P, Jiang W, Du H, Shao J, Lu B, Wang J, Zou D.

J Endocrinol Invest. 2010 Jul-Aug;33(7):483-8. doi: 10.3275/6796. Epub 2010 Jan 22.


Plasma leptin is independently associated with the intima-media thickness of the common carotid artery.

Ciccone M, Vettor R, Pannacciulli N, Minenna A, Bellacicco M, Rizzon P, Giorgino R, De Pergola G.

Int J Obes Relat Metab Disord. 2001 Jun;25(6):805-10.


Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.

Stefan N, Machicao F, Staiger H, Machann J, Schick F, Tschritter O, Spieth C, Weigert C, Fritsche A, Stumvoll M, Häring HU.

Diabetologia. 2005 Nov;48(11):2282-91. Epub 2005 Oct 5.


The effect of a novel intergenic polymorphism (rs11774572) on HDL-cholesterol concentrations depends on TaqIB polymorphism in the cholesterol ester transfer protein gene.

Junyent M, Lee YC, Smith CE, Arnett DK, Tsai MY, Kabagambe EK, Straka RJ, Province M, An P, Lai CQ, Parnell LD, Shen J, Borecki I, Ordovas JM.

Nutr Metab Cardiovasc Dis. 2010 Jan;20(1):34-40. doi: 10.1016/j.numecd.2009.02.010. Epub 2009 Apr 11.

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