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Items: 1 to 20 of 109

1.

Inhibitory Regulation of Skin Fibrosis in Systemic Sclerosis by Apelin/APJ Signaling.

Yokoyama Y, Sekiguchi A, Fujiwara C, Uchiyama A, Uehara A, Ogino S, Torii R, Ishikawa O, Motegi SI.

Arthritis Rheumatol. 2018 Oct;70(10):1661-1672. doi: 10.1002/art.40533. Epub 2018 Aug 23.

PMID:
29676521
2.

Increased expression of NAPDH oxidase 4 in systemic sclerosis dermal fibroblasts: regulation by transforming growth factor β.

Piera-Velazquez S, Makul A, Jiménez SA.

Arthritis Rheumatol. 2015 Oct;67(10):2749-58. doi: 10.1002/art.39242.

3.

The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.

Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheumatol. 2014 Nov;66(11):3140-50. doi: 10.1002/art.38819.

4.

Serum apelin levels: clinical association with vascular involvements in patients with systemic sclerosis.

Aozasa N, Asano Y, Akamata K, Noda S, Masui Y, Yamada D, Tamaki Z, Tada Y, Sugaya M, Kadono T, Sato S.

J Eur Acad Dermatol Venereol. 2013 Jan;27(1):37-42. doi: 10.1111/j.1468-3083.2011.04354.x. Epub 2011 Nov 24.

PMID:
22112232
5.

Suppressive Regulation by MFG-E8 of Latent Transforming Growth Factor β-Induced Fibrosis via Binding to αv Integrin: Significance in the Pathogenesis of Fibrosis in Systemic Sclerosis.

Fujiwara C, Uehara A, Sekiguchi A, Uchiyama A, Yamazaki S, Ogino S, Yokoyama Y, Torii R, Hosoi M, Suto C, Tsunekawa K, Murakami M, Ishikawa O, Motegi SI.

Arthritis Rheumatol. 2019 Feb;71(2):302-314. doi: 10.1002/art.40701. Epub 2019 Jan 4.

PMID:
30175895
6.

Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis.

Wu M, Pedroza M, Lafyatis R, George AT, Mayes MD, Assassi S, Tan FK, Brenner MB, Agarwal SK.

Arthritis Rheumatol. 2014 Apr;66(4):1010-21. doi: 10.1002/art.38275.

7.

The fibrotic phenotype of systemic sclerosis fibroblasts varies with disease duration and severity of skin involvement: reconstitution of skin fibrosis development using a tissue engineering approach.

Corriveau MP, Boufaied I, Lessard J, Chabaud S, Senécal JL, Grodzicky T, Chartier S, Raymond Y, Moulin VJ.

J Pathol. 2009 Mar;217(4):534-42. doi: 10.1002/path.2482.

PMID:
19086038
8.

Bosentan reverses the pro-fibrotic phenotype of systemic sclerosis dermal fibroblasts via increasing DNA binding ability of transcription factor Fli1.

Akamata K, Asano Y, Aozasa N, Noda S, Taniguchi T, Takahashi T, Ichimura Y, Toyama T, Sato S.

Arthritis Res Ther. 2014 Apr 3;16(2):R86. doi: 10.1186/ar4529.

9.

A potential contribution of altered cathepsin L expression to the development of dermal fibrosis and vasculopathy in systemic sclerosis.

Yamashita T, Asano Y, Taniguchi T, Nakamura K, Saigusa R, Takahashi T, Ichimura Y, Toyama T, Yoshizaki A, Miyagaki T, Sugaya M, Sato S.

Exp Dermatol. 2016 Apr;25(4):287-92. doi: 10.1111/exd.12920. Epub 2016 Feb 11.

PMID:
26661692
10.

[THE ROLE OF SEMAPHORIN 7A IN SYSTEMIC SCLEROSIS].

Rimar D, Slobodin G, Rosner I, Rozenbaum M, Kaly L, Boulman N, Jiries N, Awisat A, Vadasz Z.

Harefuah. 2017 Jul;156(7):418-421. Hebrew.

PMID:
28786275
11.

Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.

Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheum. 2012 May;64(5):1642-52. doi: 10.1002/art.33501.

12.

Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis.

Manetti M, Romano E, Rosa I, Guiducci S, Bellando-Randone S, De Paulis A, Ibba-Manneschi L, Matucci-Cerinic M.

Ann Rheum Dis. 2017 May;76(5):924-934. doi: 10.1136/annrheumdis-2016-210229. Epub 2017 Jan 6.

PMID:
28062404
13.

An Autotaxin/Lysophosphatidic Acid/Interleukin-6 Amplification Loop Drives Scleroderma Fibrosis.

Castelino FV, Bain G, Pace VA, Black KE, George L, Probst CK, Goulet L, Lafyatis R, Tager AM.

Arthritis Rheumatol. 2016 Dec;68(12):2964-2974. doi: 10.1002/art.39797.

14.

Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosis.

Del Galdo F, Sotgia F, de Almeida CJ, Jasmin JF, Musick M, Lisanti MP, Jiménez SA.

Arthritis Rheum. 2008 Sep;58(9):2854-65. doi: 10.1002/art.23791.

15.

The Antiretroviral Agent Nelfinavir Mesylate: A Potential Therapy for Systemic Sclerosis.

Sanchez CG, Molinski SV, Gongora R, Sosulski M, Fuselier T, MacKinnon SS, Mondal D, Lasky JA.

Arthritis Rheumatol. 2018 Jan;70(1):115-126. doi: 10.1002/art.40326. Epub 2017 Dec 8.

16.

The apelin-APJ axis: A novel potential therapeutic target for organ fibrosis.

Huang S, Chen L, Lu L, Li L.

Clin Chim Acta. 2016 May 1;456:81-88. doi: 10.1016/j.cca.2016.02.025. Epub 2016 Mar 2. Review.

PMID:
26944568
17.

Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.

Kawaguchi Y, Takagi K, Hara M, Fukasawa C, Sugiura T, Nishimagi E, Harigai M, Kamatani N.

Arthritis Rheum. 2004 Jan;50(1):216-26.

18.

The inflammasome activating caspase 1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis.

Artlett CM, Sassi-Gaha S, Rieger JL, Boesteanu AC, Feghali-Bostwick CA, Katsikis PD.

Arthritis Rheum. 2011 Nov;63(11):3563-74. doi: 10.1002/art.30568.

19.

Endothelin 1 contributes to the effect of transforming growth factor beta1 on wound repair and skin fibrosis.

Lagares D, García-Fernández RA, Jiménez CL, Magán-Marchal N, Busnadiego O, Lamas S, Rodríguez-Pascual F.

Arthritis Rheum. 2010 Mar;62(3):878-89. doi: 10.1002/art.27307.

20.

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.

Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, Palumbo K, Zwerina J, Nevskaya T, Gay S, Distler O, Schett G, Distler JH.

Arthritis Rheum. 2010 Jan;62(1):280-90. doi: 10.1002/art.25056.

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